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1.YingWang#,RunzeGao#,JingWu#,Yi-ChunXiong,JiaWei,SipinZhang,BeiYang,JiaChen*andLiYang*.ComparisonofcytosinebaseeditorsanddevelopmentoftheBEable-GPSdatabasefortargetingpathogenicSNVs.GenomeBiol,2019,20:218-224
2.JiaChen*,BeiYang*andLiYang*.ToBEornottoBE,thatisthequestion.NatBiotechnol,2019,37:520-522
3.BeiYang*,LiYang*andJiaChen*.DevelopmentandApplicationofBaseEditors.CRISPRJ,2019,2:91-104
4.JiananLi#,ZhenLiu#,ShishengHuang#,XiaoWang,GuangleiLi,YutingXu,WenxiaYu,ShanshanChen,YuZhang,HanhuiMa,ZunfuKe,JiaChen*,QiangSun*andXingxuHuang*.EfficientbaseeditinginG/C-richregionstomodelandrogeninsensitivitysyndrome.CellRes,2019,29:174-176
5.XiaoWang#,JiananLi#,YingWang#,BeiYang#,JiaWei#,JingWu,RuixuanWang,XingxuHuang*,JiaChen*andLiYang*.EfficientbaseeditinginmethylatedregionswithahumanAPOBEC3A-Cas9fusion.NatBiotechnol,2018,36:946-949(HighlightedbyNicoleRusk,Betterbaseeditors.NatMethods,2018,15:763)
6.YantingZeng#,JiananLi#,GuangleiLi#,ShishengHuang,WenxiaYu,YuZhang,DunjinChen,JiaChen,JianqiaoLiu*andXingxuHuang*.CorrectionoftheMarfanSyndromepathogenicFBN1mutationbybaseeditinginhumancellsandheterozygousembryos.MolTher,2018,26:2631-2637
7.ZhenLiu#,ZongyangLu#,GuangYang#,ShishengHuang,GuangleiLi,SongjieFeng,YajingLiu,JiananLi,WenxiaYu,YuZhang,JiaChen,QiangSun*andXingxuHuang*.EfficientgenerationofmousemodelsofhumandiseasesviaABE-andBE-mediatedbaseediting.NatCommun,2018,9:2338
8.WenJiang#,SongjieFeng#,ShishengHuang,WenxiaYu,GuangleiLi,GuangYang,YajingLiu,YuZhang,LeiZhang,YuHou,JiaChen,JiepingChen*andXingxuHuang*.BE-PLUS:anewbaseeditingtoolwithbroadenededitingwindowandenhancedfidelity.CellRes,2018,28:855-861
9.JiaChen,WeizhiJi,PrashantMaliandAprilPawluk.TheFutureofGenomeEditing.Cell,2018,173:1311-1313
10.XiaosaLi#,YingWang#,YajingLiu#,BeiYang#,XiaoWang,JiaWei,ZongyangLu,YuxiZhang,JingWu,XingxuHuang*,LiYang*andJiaChen*.Baseeditingwithacpf1-cytidinedeaminasefusion.NatBiotechnol,2018,36:324-327(HighlightedinToolsinBrief,Expandingtherangeofbaseeditors.NatMethods,2018,15:314)
11.LiqunLei#,HongquanChen#,WeiXue#,BeiYang#,BianHu#,JiaWei,LijieWang,YiqiangCui,WeiLi,JianyingWang,LeiYan,WanjingShang,JiminGao,JiahaoSha,MinZhuang,XingxuHuang,BinShen*,LiYang*andJiaChen*.APOBEC3inducesmutationsduringrepairofCRISPR–Cas9-generatedDNAbreaks.NatStructMolBiol,2018,25:45-52
12.LijieWang#,WeiXue#,LeiYan#,XiaosaLi,JiaWei,MiaomiaoChen,JingWu,BeiYang*,LiYang*andJiaChen*.Enhancedbaseeditingbyco-expressionoffreeuracilDNAglycosylaseinhibitor.CellRes,2017,27:1289-1292
13.GuangleiLi,YajingLiu,YantingZeng,JiananLi,LijieWang,GuangYang,DunjinChen,XiaoyunShang,JiaChen,XingxuHuang*andJianqiaoLiu*.Highlyefficientandprecisebaseeditingindiscardedhumantripronuclearembryos.ProteinCell,2017,8:776-779
14.BeiYang*,XiaosaLi,LiqunLeiandJiaChen*.APOBEC:frommutatortoeditor.JGenetGenomics,2017,44:423-437
15.JiaChenandAnthonyV.Furano*.Breakingbad:ThemutageniceffectofDNArepair.DNARepair,2015,32:43-51
16.JiaChen,BrendanF.MillerandAnthonyV.Furano*.RepairofnaturallyoccurringmismatchescaninducemutationsinflankingDNA.eLife,2014,3:e02001(HighlightedbySamuelH.Wilson,ThedarksideofDNArepair.eLife,2014,3:e03068)
17.Guang-JingHu#,JiaChen#,Xiao-NanZhao#,Jia-JiaXu,Dong-QingGuo,MingLu,MingZhu,YingXiong,QinLi,CatherineCYChang,Bao-LiangSong,Ta-YuanChangandBo-LiangLi*.ProductionofACAT156-kDaisoforminhumancellsviatrans-splicinginvolvingtheampicillinresistancegene.CellRes,2013,23:1007-1024(Coverstory,HighlightedbyChristianPreußerandAlbrechtBindereif,Exo-endotranssplicing:anewwaytolink.CellRes,2013,23:1071-1072)
18.LeiLei,YingXiong,JiaChen,Jin-BoYang,YiWang,Xin-YingYang,CantherineC.Y.Chang,Bao-LiangSong,Ta-YuanChangandBo-LiangLi*.TNF-alphastimulatestheACAT1expressionindifferentiatingmonocytestopromotetheCE-ladencellformation.JLipidRes,2009,50:1057-1067
19.Xiao-NanZhao#,JiaChen#,LeiLei,Guang-JingHu,YingXiong,Jia-JiaXu,QinLi,Xin-YingYang,CatherineCYChang,Bao-LiangSong,Ta-YuanChangandBo-LiangLi*.Theoptionallong5'-untranslatedregionofhumanACAT1mRNAsimpairstheproductionofACAT1proteinbypromotingitsmRNAdecay.ActaBiochimBiophysSin,2009,41:30-41
20.JiaChen#,Xiao-NanZhao#,LiYang,Guang-JingHu,MingLu,YingXiong,Xin-YingYang,CatherineCYChang,Bao-LiangSong,Ta-YuanChangandBo-LiangLi*.RNAsecondarystructureslocatedintheinterchromosomalregionofhumanACAT1chimericmRNAarerequiredtoproducethe56-kDaisoform.CellRes,2008,18:921-936
21.Bo-LiangLi*,Ta-YuanChang,JiaChen,CatherineCYChangandXiao-NanZhao.HumanACAT1geneexpressionanditsinvolvementinthedevelopmentofatherosclerosis.FutureCardiol,2006,2:93-99
22.LiYang,OneilLee,JiaChen,JiangChen,CatherineC.Y.Chang,PeiZhou,Zhen-ZhenWang,Han-HuiMa,Hui-FangSha,Jiu-XianFeng,YiWang,Xin-YingYang,LiWang,RuhongDong,KimOrnvold,Bo-LiangLi*andTa-YuanChang*.Humanacyl-coenzymeA:cholesterolacyltransferase1(Acat1)sequenceslocatedintwodifferentchromosomes(7and1)arerequiredtoproduceanovelACAT1isoenzymewithadditionalsequenceattheN-terminal.JBiolChem,2004,279:46253-46262
23.LiYang,Jin-BoYang,JiaChen,Guang-YaoYu,PeiZhou,LeiLei,Zhen-ZhenWang,CatherineC.Y.Chang,Xin-YingYang,Ta-YuanChang*andBo-LiangLi*.EnhancementofhumanACAT1geneexpressiontopromotethemacrophage-derivedfoamcellformationbydexamethasone.CellRes,2004,14:315-323(Coverstory)