Liu, Guozhen - University of New South Wales - Graduate School of Biomedical Engineering

个人简介

A/Prof Guozhen Liu is an ARC Future Fellow and Associate Professor at Graduate School of Biomedical Engineering, UNSW. Gaining her PhD degree in Chemistry in 2006 under the supervision of Prof Justin Gooding at UNSW, Liu is recognised for her innovative cross-disciplinary research in the area of biosensors, point-of-care diagnostics, and biomedical devices. She conducted her postdoctoral research at CSIRO (2006-2008) and UNSW (2008-2010), respectively before she accepted a faculty position as Associate Professor at the Central China Normal University, China (2010-2015). In 2015 Liu moved back to Sydney and worked as a Senior Research Fellow at ARC Centre of Excellence for Nanoscale BioPhtotnics (CNBP), Macquarie University before she was awarded the prestigious ARC Future Fellowship in 2016. Liu’s research career has alternated between industrial and academic research. Besides building effective collaborations within academia, she has maintained close engagement with the industry sector in the conduction of translational research. Liu’s industrial experience includes four years spent as R&D Manager for AgaMatrix Inc. (2010-2015), working for the US based company in China. This position saw her developing medical devices including glucose test strips and glucose meters. The sensing technologies described in her patents have attracted the attention and investment of industry end-users, such as AstraZeneca, BioLegend, Regeneus Ltd and AgaMatrix Inc. These technologies have been, or are in the process of being commercialised. Liu has attracted more than $5M in national and international research funding since 2015.

研究领域

Sensor Technology (Chemical aspects); Electroanalytical Chemistry; Immunological and Bioassay Methods; Nanobiotechnology; Nanoscale characterisation; Nanomaterials; Nanomedicine; Biomedical engineering

近期论文

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Shen Z; Huang J; Wei H; Niu H; Li B; Li R; Liu G, 2020, 'Validation of an in vivo electrochemical immunosensing platform for simultaneous detection of multiple cytokines in Parkinson's disease mice model', Bioelectrochemistry, vol. 134, http://dx.doi.org/10.1016/j.bioelechem.2020.107532 Ni S; Shen Z; Zhang P; Liu G, 2020, 'Enhanced performance of an electrochemical aptasensor for real-time detection of vascular endothelial growth factor (VEGF) by nanofabrication and ratiometric measurement', Analytica Chimica Acta, vol. 1121, pp. 74 - 82, http://dx.doi.org/10.1016/j.aca.2020.05.003 Hassanzadeh-Barforoushi A; Warkiani ME; Gallego-Ortega D; Liu G; Barber T, 2020, 'Capillary-assisted microfluidic biosensing platform captures single cell secretion dynamics in nanoliter compartments', Biosensors and Bioelectronics, vol. 155, http://dx.doi.org/10.1016/j.bios.2020.112113 Rani S; Bandyopadhyay-Ghosh S; Ghosh SB; Liu G, 2020, 'Advances in Sensing Technologies for Monitoring of Bone Health', Biosensors, vol. 10, http://dx.doi.org/10.3390/bios10040042 Luo Z; Lv T; Zhu K; Li Y; Wang L; Gooding JJ; Liu G; Liu B, 2020, 'Paper-Based Ratiometric Fluorescence Analytical Devices towards Point-of-Care Testing of Human Serum Albumin', Angewandte Chemie - International Edition, vol. 59, pp. 3131 - 3136, http://dx.doi.org/10.1002/anie.201915046 Deng F; Arman A; Goldys EM; Hutchinson MR; Liu G, 2020, 'A Method for in Vivo Quantification of Cytokine IL-1β in the Rat Intrathecal Space', ACS Applied Bio Materials, vol. 3, pp. 539 - 546, http://dx.doi.org/10.1021/acsabm.9b00958 Ni S; Qiao L; Shen Z; Gao Y; Liu G, 2020, 'Physical absorption vs covalent binding of graphene oxide on glassy carbon electrode towards a robust aptasensor for ratiometric electrochemical detection of vascular endothelial growth factor (VEGF) in serum', Electrochimica Acta, vol. 331, http://dx.doi.org/10.1016/j.electacta.2019.135321 Cao C; Jin R; Wei H; Liu Z; Ni S; Liu GJ; Young HA; Chen X; Liu G, 2020, 'Adaptive in vivo device for theranostics of inflammation: Real-time monitoring of interferon-γ and aspirin', Acta Biomaterialia, vol. 101, pp. 372 - 383, http://dx.doi.org/10.1016/j.actbio.2019.10.021 Arman A; Deng F; Goldys EM; Liu G; Hutchinson MR, 2020, 'In vivo intrathecal IL-1β quantification in rats: Monitoring the molecular signals of neuropathic pain', Brain, Behavior, and Immunity, http://dx.doi.org/10.1016/j.bbi.2020.04.009 Liu G; Cao C; Ni S; Feng S; Wei H, 2019, 'On-chip structure-switching aptamer-modified magnetic nanobeads for the continuous monitoring of interferon-gamma ex vivo', Microsystems and Nanoengineering, vol. 5, http://dx.doi.org/10.1038/s41378-019-0074-1 Liu G; Bursill C; Cartland SP; Anwer AG; Parker LM; Zhang K; Feng S; He M; Inglis DW; Kavurma MM; Hutchinson MR; Goldys EM, 2019, 'A Nanoparticle-Based Affinity Sensor that Identifies and Selects Highly Cytokine-Secreting Cells', iScience, vol. 20, pp. 137 - 147, http://dx.doi.org/10.1016/j.isci.2019.09.019 Deng F; Li Y; Hossain MJ; Kendig MD; Arnold R; Goldys EM; Morris MJ; Liu G, 2019, 'Polymer brush based fluorescent immunosensor for direct monitoring of interleukin-1β in rat blood', Analyst, vol. 144, pp. 5682 - 5690, http://dx.doi.org/10.1039/c9an01300h Alhamoud Y; Yang D; Fiati Kenston SS; Liu G; Liu L; Zhou H; Ahmed F; Zhao J, 2019, 'Advances in biosensors for the detection of ochratoxin A: Bio-receptors, nanomaterials, and their applications', Biosensors and Bioelectronics, vol. 141, http://dx.doi.org/10.1016/j.bios.2019.111418 Dang BV; Hassanzadeh-Barforoushi A; Syed MS; Yang D; Kim SJ; Taylor RA; Liu GJ; Liu G; Barber T, 2019, 'Microfluidic Actuation via 3D-Printed Molds toward Multiplex Biosensing of Cell Apoptosis', ACS Sensors, vol. 4, pp. 2181 - 2189, http://dx.doi.org/10.1021/acssensors.9b01057 Li Y; Liu L; Liu G, 2019, 'CRISPR/Cas Multiplexed Biosensing: A Challenge or an Insurmountable Obstacle?', Trends in Biotechnology, vol. 37, pp. 792 - 795, http://dx.doi.org/10.1016/j.tibtech.2019.04.012 Zhang F; Deng F; Liu GJ; Middleton R; Inglis DW; Anwer A; Wang S; Liu G, 2019, 'IFN-γ-induced signal-on fluorescence aptasensors: From hybridization chain reaction amplification to 3D optical fiber sensing interface towards a deployable device for cytokine sensing', Molecular Systems Design and Engineering, vol. 4, pp. 872 - 881, http://dx.doi.org/10.1039/c9me00047j Deng F; Goldys EM; Liu G, 2019, 'Molecularly imprinted polymer-based reusable biosensing device on stainless steel for spatially localized detection of cytokine IL-1Β', Sensors and Actuators, B: Chemical, vol. 292, pp. 277 - 283, http://dx.doi.org/10.1016/j.snb.2019.04.142 Li Y; Li S; Wang J; Liu G, 2019, 'CRISPR/Cas Systems towards Next-Generation Biosensing', Trends in Biotechnology, vol. 37, pp. 730 - 743, http://dx.doi.org/10.1016/j.tibtech.2018.12.005 Liu L; Yang D; Liu G, 2019, 'Signal amplification strategies for paper-based analytical devices', Biosensors and Bioelectronics, vol. 136, pp. 60 - 75, http://dx.doi.org/10.1016/j.bios.2019.04.043 Jiang T; Zhou L; Liu H; Zhang P; Liu G; Gong P; Li C; Tan W; Chen J; Cai L, 2019, 'Monitorable Mitochondria-Targeting DNAtrain for Image-Guided Synergistic Cancer Therapy', Analytical Chemistry, vol. 91, pp. 6996 - 7000, http://dx.doi.org/10.1021/acs.analchem.9b01777 Wen K; Xu X; Chen J; Lv L; Wu L; Hu Y; Wu X; Liu G; Peng A; Huang H, 2019, 'Triplet Tellurophene-Based Semiconducting Polymer Nanoparticles for Near-Infrared-Mediated Cancer Theranostics', ACS Applied Materials and Interfaces, vol. 11, pp. 17884 - 17893, http://dx.doi.org/10.1021/acsami.9b05196