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个人简介

Ph.D. Rutgers University Ceramic Science and Engineering M.S. Rutgers University Ceramic Science and Engineering B.S. Rutgers University Ceramic Science and Engineering Professional Experience 2008 Distinguished Professor of Chemical and Nuclear Engineering and Molecular Genetics and Microbiology • University of New Mexico, Albuquerque, NM. 2006 - Present: Regents' Professor of Chemical and Nuclear Engineering and Molecular Genetics and Microbiology • University of New Mexico, Albuquerque, NM. 2003 - Present: Laboratory Fellow (one of two lab-wide), Sandia National Laboratories (SNL), Albuquerque. 1999 - 2006: Professor of Chemistry and Chemical and Nuclear Engineering • University of New Mexico, Albuquerque, NM. 1999-2003: Senior Scientist, Chemical Synthesis and Nanomaterials Department • Sandia National Laboratories. 1991-99: Distinguished National Laboratory Professor of Chemistry and Chemical and Nuclear Engineerin• University of New Mexico, Albuquerque, NM. 1991-98: Distinguished Member of the Technical Staff, Direct Fabrication Dept • Sandia National Laboratories. 1979-91: Member of the Technical Staff, Chemistry and Ceramics Department • Sandia National Laboratories.

研究领域

Conjugated Polymer Silica Nanocomposites. Photoresponsive nanocomposite membranes for nanovalves. Ion Channel Sensors. Super-hydrophobic surfaces. Nanostructured molecular sieve membranes. Mesoporous Micro- and Nano-particles prepared by Evaporation-Induced Self Assembly within Aerosols. Synthesis and Characterization of Germanium Nanocrystals. Nanoporous silica composite material for corrosion inhibition of aluminum alloys

近期论文

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"Sol–Gel-Based Advanced Porous Silica Materials for Biomedical Applications" Qi Lei, Jimin Guo, Achraf Noureddine, Aixia Wang, Stefan Wuttke, C. Jeffrey Brinker,* and Wei Zhu, Advanced Functional Materials, March 2020. " On the issue of transparency and reproducibility in nanomedicine" Hon S. Leong, Kimberly S. Butler, C. Jeffrey Brinker, May Azzawi, Steve Conlan9, Christine Dufés, Andrew Owen, Steve Rannard9, Chris Scott, Chunying Chen, Marina A. Dobrovolskaia, Serguei V. Kozlov, Adriele Prina-Mello, Ruth Schmid21, Peter Wick, Fanny Caputo, Patrick Boisseau, Rachael M. Crist, Scott E. McNeil, Bengt Fadeel, Lang Tran, Steffen Foss Hansen, Nanna B. Hartmann, Lauge P. W. Clausen, Lars M. Skjolding, Anders Baun, Marlene Ågerstrand, Zhen Gu, Dimitrios A. Lamprou, Clare Hoskins, Leaf Huang, Wantong Song, Huiliang Cao34, Xuanyong Liu, Klaus D. Jandt, Wen Jiang, Betty Y. S. Kim, Korin E. Wheeler, Andrew J. Chetwynd, Iseult Lynch, Sayed Moein Moghimi, André Nel, Tian Xia, Paul S. Weiss, Bruno Sarmento, José das Neves, Hélder A. Santos, Luis Santos, Samir Mitragotri, Steve Little, Dan Peer, Mansoor M. Amiji, Maria José Alonso, Alke Petri-Fink, Sandor Balog, Aaron Lee, Barbara Drasler, Barbara Rothen-Rutishauser, Stefan Wilhelm, Handan Acar, Roger G. Harrison, Chuanbin Mao, Priyabrata Mukherjee, Rajagopal Ramesh58, Lacey R. McNally, Sara Busatto, Joy Wolfram, Paolo Bergese, Mauro Ferrari, Ronnie H. Fang, Liangfang Zhang, Jie Zheng, Chuanqi Peng, Bujie Du,Mengxiao Yu, Danielle M. Charron, Gang Zheng and Chiara Pastore* https://doi.org/10.1038/s41565-019-0496-9 " Metal-Organic Framework Nanoparticle-Assisted Cryopreservation of Red Blood Cells" Wei Zhu,‡ Jimin Guo,‡ Jacob Ongudi Agola, Jonas G. Croissant, Zihao Wang, Jin Shang, Eric Coker, Benyamin Motevalli, Andreas Zimpel, Stefan Wuttke, and C. Jeffrey Brinker. " Metal-Organic Framework Nanoparticle-Assisted Cryopreservation of Red Blood Cells" (Supporting Document) Wei Zhu,‡ Jimin Guo,‡ Jacob Ongudi Agola, Jonas G. Croissant, Zihao Wang, Jin Shang, Eric Coker, Benyamin Motevalli, Andreas Zimpel, Stefan Wuttke, and C. Jeffrey Brinker. " Predicting breast cancer response toneoadjuvant chemotherapy based on tumorvascular features in needle biopsies " Terisse A. Brocato, Ursa Brown-Glaberman, Zhihui Wang, Reed G. Selwyn, Colin M. Wilson, Edward F. Wyckoff, Lesley C. Lomo, Jennifer L. Saline, Anupama Hooda-Nehra, Renata Pasqualini, Wadih Arap, C. Jeffrey Brinker, Vittorio Cristini.JCI Insight. 2019; 4(8): e126518. https://doi.org/10.1172/jci.insight.126518. " Mathematical modeling in cancer nanomedicine: a review" Dogra, P., Butner, J.D., Chuang, Y. et al. Biomed Microdevices (2019) 21: 40. "Predicting breast cancer response to neoadjuvant chemotherapy based on tumor vascular features in needle biopsies.". Brocato, T.A., Brown-Glaberman, U., Wang, Z., Selwyn, R.G., Wilson, C.M., Wyckoff, E.F., Lomo, L.C., Saline, J.L., Hooda-Nehra, A., Pasqualini, R. and Arap, W. JCI insight 2019 "Conversion of Metal-Organic Cage to Ligand-Free Ultrasmall Noble Metal Nanocluster Catalysts Confined within Mesoporous Silica Nanoparticle Supports.". Zhu, W., A. Noureddine, J. Y. Howe, J. Guo, and C. J. Brinker. Nano letters 2019 "Modular Metal–Organic Polyhedra Superassembly: From Molecular‐Level Design to Targeted Drug Delivery. Advanced Materials",. Wei Zhu, Jimin Guo, Yi Ju, Rita E Serda, Jonas G Croissant, Jin Shang, Eric Coker, Jacob Ongudi Agola, Qi‐Zhi Zhong, Yuan Ping, Frank Caruso, C Jeffrey Brinker. Advanced Materials 2019,, p.1806774. "Osteotropic nanoparticles for prevention or treatment of bone metastases.". Durfee, Paul N., Charles Jeffrey Brinker, Yu-Shen Lin, and Hon Leong. U.S. Patent Application 2019,, 16/068,235, "Nanoscale flow cytometry to distinguish subpopulations of prostate extracellular vesicles in patient plasma.". Padda, Ranjit S., Florence K. Deng, Sabine I. Brett, Colleen N. Biggs, Paul N. Durfee, Charles J. Brinker, Karla C. Williams, and Hon S. Leong. The Prostate 2019 "Engineering of large-pore lipid-coated mesoporous silica nanoparticles for dual cargo delivery to cancer cells.". Noureddine, A., Hjelvik, E.A., Croissant, J.G., Durfee, P.N., Agola, J.O. and Brinker, C.J., Journal of Sol-Gel Science and Technology, 89(1) 2019, 78-90 "Establishing the effects of mesoporous silica nanoparticle properties on in vivo disposition using imaging-based pharmacokinetics" P Dogra, NL Adolphi, Z Wang, YS Lin, KS Butler, PN Durfee, JG Croissant, Nature communications 9 (1), 4551 3 2018 "Lipid-Coated Mesoporous Silica Nanoparticles for the Delivery of the ML336 Antiviral to Inhibit Encephalitic Alphavirus Infection AE LaBauve", TE Rinker, A Noureddine, RE Serda, JY Howe, Scientific reports 8 (1), 13990 1 2018 "Biodegradable Silica-Based Nanoparticles: Dissolution Kinetics and Selective Bond Cleavage." JG Croissant, CJ Brinker The Enzymes 43, 181-214 1 2018 "Molecular Dynamics Simulations of the Silica–Cell Membrane Interaction: Insights on Biomineralization and Nanotoxicity" M Delle Piane, S Potthoff, CJ Brinker, L Colombi Ciacchi The Journal of Physical Chemistry C 122 (37), 21330-21343 2018 "Understanding the connection between nanoparticle uptake and cancer treatment efficacy using mathematical modeling" TA Brocato, EN Coker, PN Durfee, YS Lin, J Townson, EF Wyckoff, Scientific reports 8 (1), 7538 4 2018 "Pendant/bridged/mesoporous silsesquioxane nanoparticles: versatile and biocompatible platforms for smart delivery of therapeutics" A Noureddine, CJ Brinker Chemical Engineering Journal 340, 125-147 10 2018 "Versatile Surface Functionalization of Metal–Organic Frameworks through Direct Metal Coordination with a Phenolic Lipid Enables Diverse Applications" W Zhu, G Xiang, J Shang, J Guo, B Motevalli, P Durfee, JO Agola, Advanced Functional Materials 28 (16), 1705274 5 2018 "Uptake and intracellular fate of cholera toxin subunit b-modified mesoporous silica nanoparticle-supported lipid bilayers (aka protocells) in motoneurons MAG Porras," P Durfee, S Giambini, GC Sieck, CJ Brinker, CB Mantilla Nanomedicine: Nanotechnology, Biology and Medicine 14 (3), 661-672 1 2018

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