研究领域
(1)肿瘤药物抗癌分子机制
(2)细胞凋亡与细胞自噬
(3)肿瘤干细胞自我更新及干性维持的分子调控机制
近期论文
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1. Hui Luo, Yang Yang et al. PTEN-regulated AKT/FoxO3a/Bim signaling contributes to ROS mediated apoptosis in selenite-treated CRC cells. Cell Death &Disease: (2013) 4, 481.
2. Hui Luo, Yang Yang, et al. Selenite induces apoptosis in CRC cells via AKT-mediated inhibition of β-catenin survival axis. Cancer Letters : 2012, 315,1 (78-85)
3. Yang Yang, Hui Luo et al. Selenite-induced autophagy antagonizes apoptosis in colorectal cancer cells in vitro and in vivo. Oncology report. DOI:10.3892/or 2015.4484
4. Q. Jiang, Y.Wang, T. Li, K. Shi, Z. Li, Y. Ma, F. Li, H. Luo, Y. Yang, C. Xu, Hsp90-mediated inactivation of NF-κB switches autophagy to apoptosis through becn1 transcriptional inhibition in selenite-induced NB4 cells. Mol Biol Cell 22 (2011) 1167-1180.