个人简介
刘呈雄,男,博士,汉族,湖北随州人,1986年5月生,中共党员,2012-2015年获武汉大学生物化学与分子生物学专业博士学位。2015年12月进入三峡大学生物与制药学院天然产物研究与利用湖北省重点实验室。发表SCI收录论文目前主持的科研项目有国家自然科学基金青年基金、湖北省教育厅项目、国家重点实验室开放课题等。所在科研平台,拥有HPLC、NMR、MS等大型仪器,科研条件优越。本人对待学生真诚热情,欢迎各位同学加入我们的团队。
研究领域
药用植物及其内生菌活性次级代谢产物研究/微生物代谢调控
近期论文
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主要学术论文:(SCI收录10篇,中文CSCD核心5篇)
(1)Zhi-YingSun,Sheng-QiZuo,XiaYang,Jia-HuiLan,Cheng-XiongLiu*,Zhi-YongGuo,FanCheng,KunZou*,AspidsaponinsE-H,FournewsteroidalsaponinsfromtherhizomesofAspidistraelatiorBlumeandtheiranti-inflammatoryactivity,PhytochemistryLetters,2019,34:68-73.
(2)Qing-QingZhang,Zhi-YingSun,Xue-YunFeng,Run-JieChen,WenDeng,Yong-LiTang,Zhi-YongGuo,Cheng-XiongLiu*,Jian-FengChen,KunZou*,ThymolderivativesfromtherootsofEupatoriumchinenseandtheircytotoxicactivities,PhytochemistryLetters,2019,29:165-168.
(3)Sheng-QiZuo,Ying-NanLiu,YangYang,Zhi-QiangGuo,Cheng-XiongLiu*,Zhi-YongGuo,Hai-BoHe,XuanTu,KunZou*,AspidsaponinsA-D,FournewsteroidalsaponinsfromtherhizomesofAspidistraelatiorBlumeandtheircytotoxicity,PhytochemistryLetters,2018,25:126-131.
(4)YuXiao-Qin,ZhangQing-Qing,YanWei-Hong,WangLei,GuoZhi-Yong,YangQing-Qing,LiuCheng-Xiong*,HeHai-Bo,ZouKun*.ThreenewterpenoidsfromtheEupatoriumchinense.PhytochemistryLetters,2017,20:224-227.
(5)ZhengJu-Yan,WangQian,LiuZhao-Xia,LiuCheng-Xiong*,GuoZhi-Yong,ZhangHong-Qi,HeHai-Bo,TuXuan,ZouKun.Twonewsteroidalglycosideswithuniquestructuralfeatureof14α-hydroxy-5β-steroidsfromReineckiacarnea.Fitoterapia,2016,115:19-23.
(6)LiuCheng-Xiong*,YuXiao-Qin,GuoZhi-Yong,HeHai-Bo,TuXuan,DengZhang-Shuang,KunZou.StructuralelucidationandNMRspectralassignmentsofParaconfuranonesI-Mfromtheinsect-associatedfungusParaconiothyriumbrasiliense.MagneticResonanceinChemistry,2016,54(11):916-921.
(7)LiuCheng-Xiong,WangLei,ChenJian-Feng,GuoZhi-Yong,TuXuan,DengZhang-Shuang,ZouKun.ParaconfuranonesA-H,eightnewfuranoneanalogsfromtheinsect-associatedfungusParaconiothyriumbrasilienseMZ-1.MagneticResonanceinChemistry,2015,53(4):317-322.
(8)LiuCheng-Xiong,GuoZhi-Yong,DengZhang-Shuang,XueYan-Hong,ZouKun,ZhouYuan,HuangNian-Yu,ChengFan.NewfurostanolsaponinsfromtherhizomesofTupistrachinensis.NaturalProductResearch,2013,27(2):123-129.
(9)LiuCheng-Xiong,GuoZhi-Yong,XueYan-Hong,ZhangHong-Yan,ZhangHong-Qi,ZouKun,HuangNian-Yu.TupisteroideA-C,threenewpolyhydroxylatedsteroidalconstituentsfromtherootsofTupistrachinensis.MagneticResonanceinChemistry,2012,50(4):320-324.
(10)LiuCheng-Xiong,GuoZhi-Yong,XueYan-Hong,ChengJun,HuangNian-Yu,ZhouYuan,ChengFan,ZouKun.FivenewfurostanolsaponinsfromtherhizomesofTupistrachinensis.Fitoterapia,2012,83(2):323-328.
已申请国家发明专利2项,获得授权1项。
1.刘呈雄,郭志勇,尉小琴,等.一种内生真菌巴西类壳小圆孢菌株及其应用.中国专利:CN106010980A,2016-10-12.(已授权)
近五年科研项目(按时间倒序填写)
1、基于Pictet-Spengler反应调控川芎哚的结构多样性及其抗血小板聚集作用机制研究,国家自然科学基金青年科学基金,81803383,2019.1-2021.12,21万,主持。
2、基于H+/K+-ATPase酶研究木瓜内生真菌中的新颖艾里莫芬烷倍半萜的构效关系,湖北省教育厅中青年人才项目,Q20181201,2018.1-2019.12,2万,主持。
3、蜘蛛内生真菌抗肿瘤活性次级代谢产物研究,真菌学国家重点实验室开放课题,SKLMKF201501,2016.1-2018.12,2万,主持。