李顺 - 中国科学院水生生物研究所 -

个人简介

男，1985年生，博士，副研究员，硕士生导师。 2003-2007年武汉大学，生命科学学院，理学学士 2007-2012年中科院水生所，水生生物学专业，理学博士 2012-2017年中科院水生所，助理研究员 2017年至今中科院水生所，副研究员

研究领域

鱼类分子免疫学，侧重鱼类病毒免疫逃逸机制，以及与宿主相互作用关系

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Li, S1. Lu, LF. Feng, H. Wu, N. Chen, DD. Zhang, YB. Gui, JF. Nie, P. Zhang, YA. IFN Regulatory Factor 10 Is a Negative Regulator of the IFN Responses in Fish. J. Immunol. 2014. 193(3):1100-09. 2. Lu, LF1. Li, S1. Lu, XB. LaPatra, SE. Zhang, N. Zhang, XJ. Chen, DD. Nie, P. Zhang, YA. Spring Viremia of Carp Virus N Protein Suppresses Fish IFNφ1 Production by Targeting the Mitochondrial Antiviral Signaling Protein. J. Immunol. 2016. 196(9):3744-53. 3. Li, S1. Lu, LF. Wang, ZX. Lu, XB. Chen, DD. Nie, P. Zhang, YA. The P Protein of Spring Viremia of Car-p Virus Negatively Regulates Fish IFN Response by Inhibiting the Kinase Activity of TANK-binding kinase 1. J Virol. 2016. 23(90):10728-37. 4. Li, S1. Lu, LF. LaPatra, SE. Chen, DD. Zhang, YA. Zebrafish STAT6 negatively regulates IFNφ1 production by attenuating the kinase activity of TANK-binding kinase 1. Dev Comp Immunol. 2017. 67:189-201. 5. Li, S1. Lu, LF. Wang, ZX. Chen, DD. Zhang, YA. Fish IRF6 is a positive regulator of IFN expression and involved in both of the MyD88 and TBK1 pathways. Fish Shellfish Immunol. 2016. 57:262-8. 6. Li, S1. Guo, X1. Lu, LF. Lu, XB. Wu, N. Zhang, YA. Regulation pattern of fish irf4 (the gene encoding IFN regulatory factor 4) by STAT6, c-Rel and IRF4. Dev Comp Immunol. 2015. 51(1):65-73. 7. Lu, LF1. Li, S1. Lu, XB. Zhang, YA. Functions of the two zebrafish MAVS variants are opposite in the induction of IFN1 by targeting IRF7. Fish Shellfish Immunol. 2015. 45(2):574-82. 8. Li, S1. Sun, F. Zhang, YB. Gui, JF. Zhang, QY，Identification of DreI as an Antiviral Factor Regulated by RLR Signaling Pathway，PLos One，2012.03.07，7（3）：e32427 9. Zhang, XJ. Zhang, XY. Zhang, N. Guo, X. Peng, KS. Wu, H. Lu, LF. Wu, N. Chen, DD. Li, S. Nie, P. Zhang, YA. Distinctive structural hallmarks and biological activities of the multiple cathelicidin antimicrobial peptides in a primitive teleost fish. J. Immunol. 2015. 194(10):4974-87. 10. Du, J. Zhang, D. Zhang, W. Ouyang, G. Wang, J. Liu, X. Li, S. Ji, W. Liu, W. Xiao, WH. pVHL Negatively Regulates Antiviral Signaling by Targeting MAVS for Proteasomal Degradation J. Immunol. 2015. 195(4):1782-90. 11. Guo, X. Chen, DD. Peng, KS. Cui, ZW. Zhang, XJ. Li, S. Zhang, YA. Identification and characterization of Bacillus subtilis from grass carp (Ctenopharynodon idellus) for use as probiotic additives in aquatic feed. Fish Shellfish Immunol. 2016 52:74-84. 12. Wu, N. Zhang, XY. Huang, B. Zhang, N. Zhang, XJ. Guo, X. Chen, XL. Zhang, Y. Wu, H. Li, S. Li, AH. Zhang, YA. Investigating the potential immune role of fish NCAMs: Molecular cloning and expression analysis in mandarin fish. Fish Shellfish Immunol. 2015 46(2):765-77. 13. Zhang, YB. Liu, TK. Jiang, J. Shi, J. Liu, Y. Li, S. Gui, JF. Identification of a Novel Gig2 Gene Family Specific to Non-Amniote Vertebrates，PLos One，2013.4.4，8（4）：e60588