张燕 - 中国疾病预防控制中心病毒病预防控制所 -

研究领域

主要从事常见呼吸道感染相关病毒的实验室诊断方法、分子流行病学以及病毒变异变迁、分子进化与疾病关系的研究，同时从事麻疹等疫苗可预防疾病的实验室网络化监测技术的研究及其在省级和地市级网络实验室的推广应用。

近期论文

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Song J1, Wang H1, Ng TI2, Cui A1, Zhu S1, Huang Y3, Sun L3, Yang Z4, Yu D5, Yu P6, Zhang H7, Zhang Y8, Xu W9.Sequence Analysis of the Fusion Protein Gene of Human Respiratory Syncytial Virus Circulating in China from 2003 to 2014. Sci Rep. 2018 Dec 4;8(1):17618. doi: 10.1038/s41598-018-35894-3. Song J1, Wang H1, Shi J1,2, Cui A1, Huang Y3, Sun L3, Xiang X4, Ma C5, Yu P6, Yang Z7, Li Q8, Ng TI9, Zhang Y10, Zhang R11, Xu W12,13Sci Rep. Emergence of BA9 genotype of human respiratory syncytial virus subgroup B in China from 2006 to 2014. 2017 Dec 1;7(1):16765. doi: 10.1038/s41598-017-17055-0. Cui A1, Mao N1, Wang H1, Xu S1, Zhu Z1, Ji Y1, Ren L1, Gao L1, Zhang Y1, Xu W1. Importance of real-time RT-PCR to supplement the laboratory diagnosis in the measles elimination program in China. PLoS One. 2018 Nov 30;13(11):e0208161. doi: 10.1371/journal.pone.0208161.. Ji T1, Guo Y1, Huang W2, Shi Y3, Xu Y4, Tong W5, Yao W6, Tan Z7, Zeng H8, Ma J9, Zhao H10, Han T1, Zhang Y1, Yan D1, Yang Q1, Zhu S1, Zhang Y11, Xu W12. The emerging sub-genotype C2 of CoxsackievirusA10 Associated with Hand, Foot and Mouth Disease extensively circulating in mainland of China. Sci Rep. 2018 Sep 6;8(1):13357. doi: 10.1038/s41598-018-31616-x. Cui A1, Zhu Z1, Mao N1, Si Y2, Ma Y2, Hu Y3, Deng X3, Wang L4, Zeng L4, Zhang Y5, Xu W6. Assessment of one-dose mumps-containing vaccine effectiveness on wild-type genotype F mumps viruses circulating in mainland China. Vaccine. 2018 Sep 11;36(38):5725-5731. doi: 10.1016/j.vaccine.2018.08.028. Epub 2018 Aug 16. Meng Chen, Yan Zhang, Fang Huang, Huiling Wang, Donglei Liu, Juan Li,Lance Rodewald, Jiang Wu, Ying Deng, Wenbo Xu. Endemic and Imported Measles Virus-Associated Outbreaks among Adults, Beijing, China, 2013. Emerging Infectious Diseases.2015, 21(3):477-479. Ma C, Hao L, Zhang Y, Su Q, Rodewald L, An Z, Yu W, Ma J, Wen N, Wang H, Liang X, Wang H, Yang W, Li L, Luo H. Bull World Health Organ. Monitoring progress towards the elimination of measles in China: an analysis of measles surveillance data. 2014, 92(5):340-347. Xu S, Zhang Y, Rivailler P, Wang H, Ji Y, Zhen Z, Mao N, Li C, Bellini WJ, Xu W, Rota PA. Evolutionary genetics of genotype H1 measles viruses in China from1993 to 2012. J Gen Virol. 2014, 95(Pt 9):1892-1899. Zhang Yan, Wang H, Xu S, Mao N, Zhu Z, Shi J, Huang G, Liu C, Bo F, Feng D, Lu P, Liu Y, Wang Y, Lei Y, Chen M, Chen H, Wang C, Fu H, Li C, He J, Gao H, Gu S, Wang S, Ling H, Liu Y, Ding Z, Ba Z, Feng Y, Zheng H, Tang X, Lei Y, Xiong Y, Bellini WJ, Rota PA, Jee Y, Xu W, Measles Virology Surveillance Working Group. Monitoring progress toward measles elimination by genetic diversity analysis of measles viruses in China 2009-2010. Clin Microbiol Infect. 2014, 20(9):O566-577. Songtao Xu, Yan Zhang, Zhen Zhu, Chunyu Liu , Naiying Mao, Yixin Ji, HuilingWang, Xiaohong Jiang, Chongshan Li, Wei Tang, Daxing Feng, Changyin Wang, Lei Zheng, Yue Lei , Hua Ling, Chunfang Zhao, Yan Ma, Jilan He, Yan Wang, Ping Li, Ronghui Guan, Shujie Zhou, Jianhui Zhou, Shuang Wang, Hong Zhang, Huanying Zheng, Leng Liu, HemutiMa, Jing Guan, Peishan Lu, Yan Feng, Yanjun Zhang, Shunde Zhou, Ying Xiong, Zhuoma Ba, Hui Chen, Xiuhui Yang, Fang Bo, Yujie Ma, YongLiang, Yake Lei, SuyiGu, Wei Liu, Meng Chen, David Featherstone, Youngmee Jee, William J. Bellini, Paul A. Rota, Wenbo Xu. Genetic Characterization of the Hemagglutinin Genes of Wild-Type Measles Virus Circulating in China, 1993–2009. PLOS ONE.2013, 8(9):e73374. Yan Zhang, Xiaojuan Tan, Aili Cui, Naiying Mao, Songtao Xu, Zhen Zhu, Jianhui Zhou, Jing Shi1, Yueping Zhao, Xianjun Wang, Xueyong Huang, Shuangli Zhu, Yong Zhang, Wei Tang, Hua Ling, Wenbo Xu. Complete Genome Analysis of the C4 Subgenotype Strains of Enterovirus 71: PredominantRecombination C4 Viruses Persistently Circulating in China for 14 Years. PLoS ONE.2013, 8(2): e56341. Yan Zhang, Songtao Xu, Huiling Wang, Zhen Zhu, Yixin Ji, Chunyu Liu, Xiaojie Zhang, Liwei Sun, Jianhui Zhou, Peishan Lu, Ying Hu, Daxing Feng, Zhenying Zhang, Changyin Wang, Xueqiang Fang, Huanying Zheng, Leng Liu, Xiaodong Sun, Wei Tang, Yan Wang, Yan Liu, Hui Gao, Hong Tian, Jiangtao Ma, SuyiGu, Shuang Wang, Yan Feng, Fang Bo, Jianfengliu, Yuan Si, Shujie Zhou, Yuyan Ma, Shengwei Wu, Shunde Zhou, Fangcai Li, Zhengrong Ding, Zhaohui Yang, Paul A. Rota, David Featherstone, Youngmee Jee, William J. Bellini, Wenbo Xu. Single endemic genotype of measles virus continuously circulating in China for at least 16 years. PLoS ONE.2012, 7(4): e34401. Zeng SZ, Zhang B, Zhang Y, Xie LY, Xiong J, Yu T, Xie ZP, Gao HC, Duan ZJ. Identification of 12 Cases of Acute Measles Encephalitis Without Rash. Clin Infect Dis. 2016, 63(12):1630-1633. Song J, Wang H, Shi J, Cui A, Huang Y, Sun L, Xiang X, Ma C, Yu P, Yang Z, Li Q, Ng TI, Zhang Y, Zhang R, Xu W. Emergence of BA9 genotype of human respiratory syncytial virus subgroup B in China from 2006 to 2014. Sci Rep. 2017, 7(1):16765. Song J, Zhang Y, Wang H, Shi J, Sun L, Zhang X, Yang Z, Guan W, Zhang H, Yu P, Xie Z, Cui A, Ng TI, Xu W. Emergence of ON1 genotype of human respiratory syncytial virus subgroup A in China between 2011 and 2015. Sci Rep. 2017,14;7(1):5501. 王淑蕾,李崇山,王慧玲,唐伟,宋金华,杨玉颖,王世文,张燕,许文波.中国大陆首次发现输入性B3基因型麻疹病毒病例.病毒学报,2014, 30(5):535-540. 关静,任丽,陈涛,郭强,王慧玲,甫尔哈提,关晓冬,张燕.新疆部分地区麻疹野病毒分离与基因特征分析. 疾病监测, 2015, 30(9): 723-726. 任丽,王慧玲,王常银,房学强,许文波,王英,张燕. 2013～2014年中国大陆四株不同基因型麻疹病毒分离株血凝素基因特征分析. 病毒学报. 2016, 32(4):453-458. 王慧玲,毛乃颖,任丽,高凌玉,朱贞,许松涛,崔爱利,张燕,许文波.中国2015年麻疹风疹实验室网络运转与评价.中国疫苗和免疫. 2017; 23(2):157-161. 高凌玉,张燕,王慧玲,任丽,毛乃颖,许松涛,许文波.我国大陆流行的麻疹病毒H1基因型的血凝素基因变异特征,1993-2013. 病毒学报,2017,33(1): 68-73.

学术兼职

中华医学会医学病毒学分会青年委员，北京市科委技术专家，北京市疾病预防控制中心疫苗遴选专家委员会专家，病毒学报编委，中国疫苗与免疫编委，中国病毒病杂志青年编委，中国疾病监测通讯编辑