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个人简介

Professor Steven C. Zimmerman attended the University of Wisconsin as an undergraduate. After obtaining his B.S. in 1979, he moved to New York City where in 1983 he obtained his Ph.D. from Columbia University. He held an NSF-NATO Postdoctoral Fellowship at the University of Cambridge in England and joined the Illinois faculty in 1985.

近期论文

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Small Molecules that Target the Toxic RNA in Myotonic Dystrophy Type?2, 3/20/2014, Lien Nguyen, JuYeon Lee, and Steven C. Zimmerman ChemMedChem 2014, in press , DOI: 10.1002/cmdc.201402095 Practical Synthesis of Water-Soluble Organic Nanoparticles with a Single Reactive Group and a Functional Carrier Sca?old, 6/18/2014, Yugang Bai, Hang Xing, N. Gabriel Lemcoff, Yi Lu, and Steven C. Zimmerman Chem. Sci. 2014, 5, 2862-2868. , DOI: 10.1039/C4SC00700J Targeting Toxic RNAs that Cause Myotonic Dystrophy Type 1 (DM1) with a Bisamidinium Inhibitor, 3/20/2014, Chun-Ho Wong, Lien Nguyen, Jessie Peh, Long M. Luu, Jeannette S. Sanchez, Stacie L. Richardson, Tiziano Tuccinardi, Tsoi Ho, Edwin H. Y. Chan, Wood-Yee Chan, Anne M. Baranger, Paul J. Hergenrother, and Steven C. Zimmerman J. Am. Chem. Soc. 2014, 136, 6355–6361. , DOI: 10.1021/ja5012146 Isaiah Shavitt: Computational Chemistry Pioneer, 3/20/2014, Steven C. Zimmerman and Russell M. Pitzer Theor. Chem. Acct. 2014, 113, (1488), 1-7. , DOI:10.1007/s00214-014-1488-3 Proton Switch for Modulating Oxygen Reduction by a Copper Electrocatalyst Embedded in a Hybrid Bilayer Membrane, 3/20/2014, Christopher J. Barile, Edmund C. M. Tse, Ying Li, Thomas B. Sobyra, Steven C. Zimmerman, Ali Hosseini, and Andrew A. Gewirth Nature Mater. 2014, 13, 619–623. , DOI: 10.1038/nmat3974 Developing Bivalent Ligands to Target CUG Triplet Repeats as the Causative Agent of Myotonic Dystrophy Type 1, 3/20/2014, Amin Haghighat Jahromi, Yuan Fu, Lien Nguyen, Kali A. Miller, Anne M. Baranger, and Steven C. Zimmerman J. Med. Chem. 2013, 56(23), 9471–9481. , DOI: 10.1021/jm400794z A Polymeric Fastener to Localize Gadolinium on a Liposome Surface for Enhanced Magnetic Resonance Imaging, 3/20/2014, Cartney E. Smith , Artem Shkumatov , Sarah G. Withers , James F. Glockner , Sanjay Misra , Edward J. Roy , Chun-Ho Wong , Steven C. Zimmerman , and Hyunjoon Kong ACS Nano 2013, 7, 9599-9610. , DOI: 10.1021/nn4026228 Hydrogen Bonding Modules for Use in Supramolecular Polymers, 3/20/2014, Si Kyung Yang and Steven C. Zimmerman, Isr. J. Chem. 2013, 53, 511-520. Cover Article. , DOI: 10.1002/ijch.201300045 Supramolecular Chemistry for Biology, Materials and Medicine, 3/20/2014, Alanna Schepartz and Steven C. Zimmerman Isr. J. Chem. 2013, 53, 495-496. , DOI: 10.1002/ijch.201310007. Ring-fused BODIPY as a Single-Molecule Optical Probe with Suppressed Blinking and Long Lifetime, 3/20/2014, Si Kyung Yang, Xinghua Shi, Taekjip Ha, and Steven C. Zimmerman Nature Chem. 2013, 5, 692-697. , DOI:10.1038/nchem.1706. Single molecule study of the CUG Repeat?MBNL1 Interaction and its Inhibition by Small Molecule, 3/20/2014, Amin Haghighat Jahromi, Masayoshi Honda, Steven C. Zimmerman, and Maria Spies Nucl. Acids Res. 2013, 41 (13), 6687-6697. , DOI: 10.1093/nar/gkt330. Cover Article. Quadruply Hydrogen Bonding Modules as Highly Selective Nanoscale Adhesive Agents, 3/20/2014, Yagang Zhang, Cyrus A. Anderson, and Steven C. Zimmerman Org. Lett. 2013, 15, 3506–3509. , DOI: 10.1021/ol401035t. Leukocyte-Mimicking Stem Cell Delivery via In situ Coating of Cells with a Bioactive Polyglycerol, 3/20/2014, John J. Schmidt, Jae Hyun Jeong, Richie Kohman, Andrew Zill, Ross DeVolder, Steven C. Zimmerman, and Hyunjoon Kong J. Am. Chem. Soc. 2013, 135, 8770-8773. , DOI: 10.1021/ja4005283. Cover Article. High-Affinity DNA Base Analogs as Supramolecular, Nanoscale Promoters of Macroscopic Adhesion9, 3/20/2014, Cyrus A. Anderson, Amanda R. Jones, Ellen M. Briggs, Eric J. Novitsky, Darrell W. Kuykendall, Nancy R. Sottos, and Steven C. Zimmerman J. Am. Chem. Soc. 2013, 135, 7288–7295. , DOI: 10.1021/ja4005283 A Novel CUGexp?MBNL1 Inhibitor with Therapeutic Potential for Myotonic Dystrophy Type 1, 3/20/2014, Amin Haghighat Jahromi, Lien Nguyen, Yuan Fu, Kali Miller, Anne M. Baranger, and Steven C. Zimmerman ACS Chem. Biol. 2013, 8, 1037-1043. , DOI: 10.1021/cb400046u. Cover Article. Orthogonality in Organic, Polymer, and Supramolecular Chemistry: from Merrifield to Click Chemistry, 3/20/2014, Chun-Ho Wong and Steven C. Zimmerman Chem. Commun. 2013, 49, 1679-1695. , DOI: 10.1039/c2cc37316e. Cover Article. Azobenzene Dye Coupled Quadruple Hydrogen Bonding Modules as Colorimetric Indicators for Supramolecular Interactions, 3/20/2014, Yagang Zhang and Steven C. Zimmerman Beilstein J. Org. Chem. 2012, 8, 486–495. , DOI: 10.3762/bjoc.8.55. Investigating the Binding Mode of an Inhibitor of the MBNL1?RNA Complex in Myotonic Dystrophy Type 1 (DM1) Leads to the Unexpected Discovery of a DNA-Selective Binder, 3/20/2014, Chun-Ho Wong, Stacie L. Richardson, Yen-Jun Ho, Alex M. H. Lucas, Tiziano Tuccinardi, Anne M. Baranger, and Steven C. Zimmerman ChemBioChem 2012, 13, 2505-2509. , DOI: 10.1002/cbic.201200602. Polyglycerol-Dendronized Perylenediimides as Stable, Water-soluble Fluorophores, 3/20/2014, Si Kyung Yang and Steven C. Zimmerman Adv. Funct. Mater. 2012, 22, 3023-3028. , DOI: 10.1002/adfm.201200004. Calix[8]arene Functionalized Polyglycerol Nanogels for Encapsulation and Stabilization of Fluorescent Dyes, 3/20/2014, Dirk Steinhilber, Florian Paulus, Andrew T. Zill, Steven C. Zimmerman and Rainer Haag MRS Proc. 2012, 1403, 185-193. , DOI: 10.1557/opl.2012.419.

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