个人简介
2017.04~今，中国科学院昆明植物研究所，硕士研究生导师
2016.10~2017.09，英国华威大学化学系，访问学者
2014.01~今，中国科学院昆明植物研究所，副研究员
2011.08~2013.12，中国科学院昆明植物研究所，助理研究员
2008.09~2011.06，中国科学院昆明植物研究所，理学博士学位
2005.09~2008.06，中国科学院昆明植物研究所，理学硕士学位
2001.09~2005.06，中国海洋大学药学院，医学学士学位
研究领域
针对糖尿病的复杂发病机制，利用课题组构建的多种酶学、细胞和动物模型，开展传统药用植物中降血糖活性分子的发现、结构修饰、功能评价和机制研究
近期论文
查看导师新发文章
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1. Zhen-Tao Deng, Ji-Jun Chen, Chang-An Geng*. ent-Labdane and ent-kaurane diterpenoids from Chelonopsis odontochila with α-glucosidase inhibitory activity. Bioorg Chem, 2020, 95, 103571.
2. Yang Pan, Zhen Gao, Xiao-Yan Huang, Ji-Jun Chen, Chang-An Geng*. Chemical and biological comparison of different parts of Paeonia suffruticosa (Mudan) based on LCMS-IT-TOF and multi-evaluation in vitro. Ind Crop Prod, 2020, 144, 112028.
3. Tong-Hua Yang, De-Xiu Yan, Xiao-Yan Huang, Bo Hou, Yun-Bao Ma, Hua Peng, Xue-Mei Zhang, Ji-Jun Chen, Chang-An Geng*. Termipaniculatones A-F, chalcone-flavonone heterodimers from Terminthia paniculata, and their protective effects on hyperuricemia and acute gouty arthritis. Phytochemistry, 2019, 164, 228–235.
4. Chen-Chen Zhang, Chang-An Geng*, Xiao-Yan Huang, Xue-Mei Zhang, Ji-Jun Chen*. Antidiabetic Stilbenes from Peony Seeds with PTP1B, α-Glucosidase, and DPPIV Inhibitory Activities. J Agric Food Chem, 2019, 67, 6765？6772.
5. Jian-Gang Zhang, Xiao-Yan Huang, Yun-Bao Ma, Xue-Mei Zhang, Ji-Jun Chen, Chang-An Geng*. Dereplication-guided isolation of a new indole alkaloid triglycoside from the hooks of Uncaria rhynchophylla by LC with ion trap time-of-flight MS. J Sep Sci, 2018, 41, 1532–1538.
6. Chang-An Geng, Tong-Hua Yang, Xiao-Yan Huang, Yun-Bao Ma, Xue-Mei Zhang, Ji-Jun Chen*. Antidepressant potential of Uncaria rhynchophylla and its active flavanol, catechin, targeting melatonin receptors. J Ethnopharmacol, 2019, 232, 39–46.
7. Chang-An Geng, Tong-Hua Yang, Xiao-Yan Huang, Jing Yang, Yun-Bao Ma, Tian-Ze Li, Xue-Mei Zhang, Ji-Jun Chen*. Anti-hepatitis B virus effects of the traditional Chinese herb Artemisia capillaris and its active enynes. J Ethnopharmacol, 2018, 224, 283–289.
8. Chang-An Geng, Xiao-Yan Huang, Yun-Bao Ma, Bo Hou, Tian-Ze Li, Xue-Mei Zhang, Ji-Jun Chen. (±)-Uncarilins A and B, dimeric isoechinulin-type alkaloids from Uncaria rhynchophylla. J. Nat. Prod. 2017, 80, 959？964.
9. Chang-An Geng, Xing-Long Chen, Ning-Jia Zhou, Hao Chen, Yun-Bao Ma, Xiao-Yan Huang, Xue-Mei Zhang, Ji-Jun Chen. LC-MS guided isolation of (±)-sweriledugenin A, a pair of enantiomeric lactones, from Swertia leducii. Org Lett. 2014, 16, 370？373.
10. Chang-An Geng, Li-Jun Wang, Xue-Mei Zhang, Yun-Bao Ma, Xiao-Yan Huang, Jie Luo, Rui-Hua Guo, Jun Zhou, Yong Shen, Ai-Xue Zuo, Zhi-Yong Jiang, Ji-Jun Chen*. Anti-hepatitis B virus active lactones from the traditional Chinese herb: Swertia mileensis. Chem-Eur J, 2011, 17, 3893–3903.
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