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个人简介

招生专业 071007-遗传学 招生方向 功能表观组学 植物生物信息学 教育背景 2003-09--2008-07 中科院遗传与发育生物学研究所 博士 1999-09--2003-07 中国海洋大学 学士 工作简历 2013-01~现在, 中国科学院上海生命科学研究院植物生理生态研究所, 研究员 2011-10~2013-01,哈佛医学院, 生物信息专家 2010-01~2011-09,波士顿大学, 生物信息博士后 2009-04~2009-12,哈佛医学院, 生物信息访问学者 2008-07~2009-04,中国农业大学, 生物信息博士后 教授课程 生物信息学 现代生物学研究方法与技术 植物功能表观组学 专利成果 ( 1 ) 基于表观组信息低成本组装解析生物核心基因组信息, 发明, 2018, 第 1 作者, 专利号: 201810266892.8 发表著作 (1) Molecular Biology of S-RNase-based Self- Incompatibility, Berlin- Heidelberg-New York: Springer-Verlag, 2008-06, 第 1 作者 科研项目 ( 1 ) 水稻粒型分子模块系统解析, 主持, 部委级, 2013-08--2018-07 ( 2 ) 多梳家族组分协同调控植物生殖发育的功能表观组研究, 主持, 国家级, 2016-01--2019-12 ( 3 ) 多Polycomb组分协同调控植物生殖发育的功能表观组研究, 主持, 省级, 2015-07--2017-06 ( 4 ) 植物生物信息与表观组学研究, 主持, 市地级, 2014-10--2017-12 ( 5 ) 生物信息基因序列的解析, 主持, 院级, 2014-07--2017-12 ( 6 ) 植物生物信息学, 主持, 市地级, 2013-01--2017-12 ( 7 ) 植物功能表观组学, 主持, 市地级, 2013-02--2019-12 ( 8 ) PRC2复合体调控拟南芥渗透胁迫响应与记忆的功能表观组研究, 主持, 国家级, 2018-01--2021-12 ( 9 ) 自交不亲和性与显花植物物种起源和演化的分子机制研究, 主持, 部委级, 2018-06--2023-05 ( 10 ) 小麦重要农艺性状基因定位高通量实验与计算流程开发, 主持, 市地级, 2019-01--2021-12

研究领域

1、作物多倍化过程中的遗传与表观遗传变化规律及进化意义 2、表观修饰复合体在发育与环境响应过程中特异性作用的分子机制 3、开发高通量测序数据辅助的小麦重要农艺性状基因定位方法

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

(1) Plant Regulomics: A Data‐driven Interface for Retrieving Upstream Regulators from Plant Multi‐omics Data, The Plant Journal, 2020, 通讯作者 (2) Enhanced sustainable green revolution yield via nitrogen-responsive chromatin modulation in rice, Science, 2020, 其他(合作组作者) (3) Genome‐wide binding analysis reveals that ANAC060 directly represses sugar‐induced ABI5 transcription in Arabidopsis, The Plant Journal, 2020, 通讯作者 (4) The bread wheat epigenomic map reveals distinct chromatin architectural and evolutionary features of functional genetic elements, Genome Biology, 2019, 通讯作者 (5) Polycomb repressive complex 2 attenuates ABA-induced senescence in Arabidopsis, The Plant Journal, 2019, 通讯作者 (6) Control of de novo root regeneration efficiency by developmental status of Arabidopsis leaf explants, Journal of Genetics and Genomics, 2019, 通讯作者 (7) H3K4me2 functions as a repressive epigenetic mark in plants, Epigenetics & Chromatin, 2019, 通讯作者 (8) Genome-wide probing RNA structure with the modified DMS-MaPseq in Arabidopsis, Methods, 2019, 通讯作者 (9) Jasmonate-mediated wound signalling promotes plant regeneration, Nature Plants, 2019, 第 10 作者 (10) Genome structure and evolution of Antirrhinum majus L, Nature Plants, 2019, 其他(合作组作者) (11) Ef-Cd Locus Shortens Rice Maturity Duration without Yield Penalty, Proceedings of the National Academy of Sciences of the United States of America, 2019, 其他(合作组作者) (12) MAP: model-based analysis of proteomic data to detect proteins with significant abundance changes, Cell Discovery, 2019, 第 9 作者 (13) Reducing expression of a nitrate-responsive bZIP transcription factor increases grain yield and N use in wheat, Plant Biotechnology Journal, 2019, 第 10 作者 (14) CGT-seq: epigenome-guided de novo assembly of the core genome for divergent populations with large genome, Nucleic Acid Research, 2018, 通讯作者 (15) Downregulation of RdDM during strawberry fruit ripening, Genome Biology, 2018, 通讯作者 (16) Quantitative integration of epigenomic variation and transcription factor binding using MAmotif toolkit identifies an important role of IRF2 as transcription activator at gene promoters, cell discovery, 2018, 通讯作者 (17) Identification of Auxin Activity Like 1, a chemical with weak functions in auxin signaling pathway, Plant Molecular Biology, 2018, 第 8 作者 (18) Genome of an allotetraploid wild peanut Arachis monticola: a de novo assembly, GigaScience, 2018, 其他(合作组作者) (19) Telobox motifs recruit CLF/SWN–PRC2 for H3K27me3 deposition via TRB factors in Arabidopsis, Nature Genetics, 2018, 其他(合作组作者) (20) GSHR, a Web-Based Platform Provides Gene Set-Level Analyses of Hormone Responses in Arabidopsis, Front. Plant Sci., 2018, 通讯作者 (21) A Pivotal Role of Cell Wall in Cadmium Accumulation in the Crassulaceae hyperaccumulator Sedum plumbizincicola, Molecular Plant, 2017, 通讯作者 (22) Critical roles of DNA demethylation in the activation of ripening-induced genes and inhibition of ripening-repressed genes in tomato fruit, Proceedings of the National Academy of Sciences, 2017, 第 7 作者 (23) Divergent regeneration-competent cells adopt a common mechanism for callus initiation in angiosperms, Regeneration, 2017, 其他(合作组作者) (24) Auxin-Independent NAC Pathway Acts in Response to Explant-Specific Wounding and Promotes Root Tip Emergence during de Novo Root Organogenesis in Arabidopsis, Plant Physiology, 2016, 第 6 作者 (25) Akt-mTORC1signaling regulates Acly to integrate metabolic input to control of macrophage activation, eLIFE, 2016, 其他(合作组作者) (26) Arabidopsis Flower and Embryo Developmental Genes are Repressed in Seedlings by Different Combinations of Polycomb Group Proteins in Association with Distinct Sets of Cis-regulatory Elements, PLoS Genetics, 2016, 通讯作者 (27) Transcription factors AS1 and AS2 interact withLHP1 to repress KNOX genes in Arabidopsis, Journal of Integrative Plant Biology, 2016, 通讯作者 (28) CARMO: a comprehensive annotation platform for functional exploration of rice multi-omics data, Plant Journal, 2015, 通讯作者 (29) Global Analysis Reveals the Crucial Roles of DNA Methylation during Rice Seed Development, Plant Physiology, 2015, 第 1 作者 (30) Htt CAG repeat expansion confers pleiotropic gains of mutant huntingtin function in chromatin regulation, Human Molecular Genetics, 2015, 第 4 作者 (31) ISWI proteins participate in the genome-wide nucleosome distribution in Arabidopsis, Plant Journal, 2014, 通讯作者 (32) Interrogating translational efficiency and lineage-specific transcriptomes using ribosome affinity purification, Proceedings of the National Academy of Sciences of the United States of America, 2013, 第 2 作者 (33) Dynamic, Sex-Differential STAT5 and BCL6 Binding to Sex-Biased, Growth Hormone-Regulated Genes in Adult Mouse Liver, Molecular and Cellular Biology, 2012, 第 1 作者 (34) CYPSI: a structure-based interface for cytochrome P450s and ligands in Arabidopsis thaliana, BMC Bioinformatics, 2012, 第 1 作者 (35) MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets, Genome Biology, 2012, 第 1 作者 (36) Impact of CUX2 on the Female Mouse Liver Transcriptome: Activation of Female-Biased Genes and Repression of Male-Biased Genes, Molecular and Cellular Biology, 2012, 第 2 作者 (37) Transcriptional Profiling of Human Liver Identifies Sex-Biased Genes Associated with Polygenic Dyslipidemia and Coronary Artery Disease, PLos One, 2011, 第 1 作者 (38) Complex modulation of androgen responsive gene expression by methoxyacetic acid, Reproductive Biology and Endocrinology, 2011, 第 1 作者 (39) Impact of methoxyacetic acid on mouse Leydig cell gene expression, Reproductive Biology and Endocrinology, 2010, 第 2 作者 (40) Peroxisomes are signaling platforms for antiviral innate immunity, Cell, 2010, 第 3 作者 (41) Roles of Proteolysis in Plant Self-Incompatibility, Annual Review of Plant Biology, 2009, 第 1 作者 (42) Genetic features of a pollen-part mutation suggest an inhibitory role for the Antirrhinum pollen self-incompatibility determinant, Plant Molecular Biology, 2009, 第 1 作者

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