个人简介
招生专业
071005-微生物学
招生方向
合成生物学
教育背景
2001-09--2004-08 华东理工大学生物工程学院 博士
教授课程
代谢工程与合成生物学
专利与奖励
1. 王勇,王国栋,刘海利,拟南芥三烯甲素及其制备,申请号:201710178601.5
2. 王勇,孙雨伟,陈卓,李建华,新型 UDP-糖基转移酶及其应用,申请号:201710758391.7
3. 王勇,郝玉有,一种阵列式高通量分离培养微生物装置,中国专利,ZL 201210548502.9
4. 王勇,郝玉有,用于发酵的棉籽蛋白及其制备方法和应用,中国专利,CN 103215310 B
5. 王勇,汪建峰,熊智强,异源合成广霍香醇的方法和微生物,中国专利,申请号:2014103093474.4
6. 王勇, 熊智强, 李诗渊, 汪建峰. 高效合成萜类化合物的重组大肠杆菌底盘细胞及其制法和应用, 中国专利, 申请号: 201310501221.2
7. 王勇, 熊智强, 宋书杰, 刘巧霞,汪建峰. 一种提高大肠杆菌异源合成聚酮类化合物的方法和用途, 中国专利, 申请号: 201410338738.9.
8. 王勇, 熊智强, 李诗渊, 汪建峰. 利用微生物生产甜菊糖苷类化合物的方法, 申请号:201310460493.2;PCT专利, 国际申请号: PCT/CN2013/084618.
9. 王勇, 熊智强, 汪建峰, 李诗渊, 刘巧霞. 一种新的贝壳烯酸-13α-羟化酶、其编码基因及其应用, 申请号:201410105875.8;PCT专利, 申请号:PCT/CN2015/074344
10. Blaine Pfeifer, Yong Wang, Genetically modified E. Coli Strains Overexpressing Genes Involved in Non-mevalonate 1-deoxy-D- xylulose-5-phosphate Synthetic Pathway and Uses Thereof’, US Patent Filed 4/2009, Application # 12/420,482.
科研项目
( 1 ) 紫杉醇等萜类化合物的异源合成, 主持, 国家级, 2012-01--2016-12
( 2 ) 新型甜菊糖苷类化合物的合成生物学设计与构建, 主持, 省级, 2014-09--2017-08
( 3 ) 高值生物基化学品关键技术研发及示范, 主持, 部委级, 2016-01--2017-12
( 4 ) 甜菊糖的合成生物制造研究, 主持, 院级, 2015-10--2017-10
( 5 ) 天然产物糖基化修饰的底盘设计及适配, 主持, 国家级, 2017-01--2020-12
参与会议
(1)Biosynthesis of Complex Natural Products in Engineered Escherichia coli 亚洲生物技术大会 YONG WANG 2011-05-11
近期论文
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(1) Thalianatriene and (-)-Retigeranin B Catalyzed by Sesterterpene Synthases from Arabidopsis thaliana, Org Lett, 2017, 通讯作者
(2) Pathway mining-based integration of critical enzyme parts for de novo biosynthesis of steviol glycosides sweetener in Escherichia coli., Cell Res, 2016, 通讯作者
(3) Construction of polyketide overproducing E. coli strains via synthetic antisense RNAs based on in silico fluxome analysis and comparative transcriptome analysis., Biotechnol J, 2016, 通讯作者
(4) Enhanced production of avermectin by deletion of type III PKSs biosynthetic cluster rpp in Streptomyces avermitilis, Lett Appl Microbiol, 2016, 通讯作者
(5) Improving heterologous polyketide production in Escherichia coli by transporter engineering, Appl Microbiol Biotechnol, 2015, 通讯作者
(6) Exploiting exogenous MEP pathway genes to improve the downstream isoprenoid pathway effects and enhance isoprenoid production in Escherichia coli, Process Biochemistry, 2015, 通讯作者
(7) Endophytes in the plant Huperzia serrata: fungal diversity and discovery of a new pentapeptide, Arch Microbiol, 2015, 通讯作者
(8) Identification of Novel Knockout Targets for Improving Terpenoids Biosynthesis in Saccharomyces cerevisiae, PLoS One, 2014, 通讯作者
(9) Significant expression of a Chinese scorpion peptide, BmK1, in Escherichia coli through promoter engineering and gene dosage strategy, Biotechnol Appl Biochem, 2014, 通讯作者
(10) Enhancing isoprenoid production through systematically assembling and modulating efflux pumps in Escherichia coli., Appl Microbiol Biotechnol, 2013, 第 4 作者
(11) Distribution and diversity of glycosylated natural product genes in marine bacteria genomes., Applied Microbiology and Biotechnology., 2011, 通讯作者
(12) In silico analysis and experimental improvement of the terpenoid precursor supply pathways for taxadiene heterologous biosynthesis in Escherichia coli., Biotechnology and Bioprocess Engineering. , 2011, 通讯作者
(13) In silico improvement of heterologous biosynthesis of erythromycin precursor 6-deoxyerythronilide B in Escherichia coli, Biotechnology and Bioprocess Engineering, 2011, 通讯作者
(14) 海洋微生物来源的天然产物开发研究进展, 应用与环境生物学报, 2011, 通讯作者
(15) Complete biosynthesis of erythromycin A and designed analogs using E. coli as a heterologous host. , Chem Biol. , 2010, 第 2 作者
(16) Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli, Science, 2010, 第 4 作者
(17) Regulation of meilingmycin in Streptomyces nanchangensis: effect of ammonium ion. , Korean J Chem Eng., 2009, 第 1 作者
(18) . Industrial bioprocess control and optimization in the context of systems biotechnology. , Biotechnology Advances, 2009, 第 1 作者
(19) DNA shuffling of methionine adenosyltransferase gene leads to improved S-adenosyl-L-methionine production in Pichia pastoris., J Biotechnol., 2009, 第 4 作者
(20) Probing the heterologous metabolism supporting 6-deoxyerythronolide B biosynthesis in E. coli., Microbial Biotechnol. , 2009, 第 2 作者
(21) 6-Deoxyerythronolide B production through chromosomal localization of the deoxyerythronolide B synthase genes in E. coli, Metabolic Engineering, 2008, 第 1 作者