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1. Sun L#, Xie C#, Wang G#, Wu Y#, Wu Q, Wang X, Liu J, Deng Y, Xia J, Chen B, Zhang S, Yun C, Lian G, Zhang X, Zhang H, Bisson WH, Shi J, Gao X, Ge P, Liu C, Krausz KW, Nichols RG, Cai J, Rimal B, Patterson AD, Wang X, Gonzalez FJ, Jiang C. Gut microbiota and intestinal FXR mediate the clinical benefits of metformin. Nat Med. 2018. PMID: 30397356
2. Xie C, Gao X, Sun D, Zhang Y, Krausz KW, Qin X, and Gonzalez FJ. Metabolic profiling of the novel HIF2α inhibitor PT2385 in vivo and in vitro. Drug Metab Dispos. 2018, 46: 336-345. PMID: 29363499.
3. Xie C, Yagai T, Luo Y, Liang X, Chen T, Wang Q, Sun D, Zhao J, Ramakrishnan SK, Sun L, Jiang C, Xue X, Tian Y, Krausz KW, Patterson AD, Liu Y, Shah YM, Wu Y, Jiang C and Gonzalez FJ. Activation of intestinal hypoxia-inducible factor 2α during obesity contributes to hepatic steatosis. Nat Med. 2017, 23: 1298-1308. PMID: 29035368
4. Li G#, Xie C#, Lu S, Nichols RG, Tian Y, Li L, Ma Y, Brocker C, Yan T, Krausz KW, Xiang R, Gavrilova O, Patterson AD and Gonzalez FJ. Intermittent fasting promotes browning of white adipose tissue and improves metabolic syndrome via shaping the gut microbiota. Cell Metab. 2017, 26: 672-685.e4. PMID: 28918936
5. Xie C, Jiang C, Shi J, Gao X, Sun D, Sun L, Wang T, Takahashi S, Anitha M, Krausz KW, Patterson AD and Gonzalez FJ. An Intestinal Farnesoid X Receptor-Ceramide Signaling Axis Modulates Hepatic Gluconeogenesis in Mice. Diabetes. 2017, 66: 613-626. PMID: 28223344
6.Shi J#, Xie C#, Liu H, Krausz KW, Bewley CA, Zhang S, Tang L, Zhou Z and Gonzalez FJ. Metabolism and Bioactivation of Fluorochloridone, a Novel Selective Herbicide, in Vivo and in Vitro. Environ Sci Technol. 2016, 50: 9652-9660. PMID: 27443216
7.Gao X#, Xie C#, Wang Y, Luo Y, Yagai T, Sun D, Qin X, Krausz KW and Gonzalez FJ. The antiandrogen flutamide is a novel aryl hydrocarbon receptor ligand that disrupts bile acid homeostasis in mice through induction of Abcc4. Biochem Pharmacol. 2016, 119: 93-104. PMID: 27569425
8. Jiang C#, Xie C#, Lv Y, Li J, Krausz KW, Shi J, Brocker CN, Desai D, Amin SG, Bisson WH, Liu Y, Gavrilova O, Patterson AD and Gonzalez FJ. Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction. Nat Commun. 2015, 6: 10166. PMID: 26670557
9. Xie C, Zhong D and Chen X. A fragmentation-based method for the differentiation of glutathione conjugates by high-resolution mass spectrometry with electrospray ionization. Anal Chim Acta. 2013, 788: 89-98. PMID: 23845486
10. Xie C, Zhou J, Guo Z, Diao X, Gao Z, Zhong D, Jiang H, Zhang L and Chen X. Metabolism and bioactivation of famitinib, a novel inhibitor of receptor tyrosine kinase, in cancer patients. Br J Pharmacol. 2013, 168: 1687-1706. PMID: 23126373
11. Xie C, Zhong D and Chen X. High-resolution mass spectrometry: a premier tool of choice for drug metabolism studies in modern drug discovery and development. LC.GC North America. 2013, 31: 784-799.
12. Xie C, Zhong D, Chen X and Kate Yu. High-Resolution Mass Spectrometry: An Ideal Premier Analytical Tool for Drug Metabolism Studies. LC.GC Europe. 2013, 26: 517-528.
13. Xie C, Zhong D, Yu K and Chen X. Recent advances in metabolite identification and quantitative bioanalysis by LC-Q-TOF MS. Bioanalysis. 2012, 4: 937-959. PMID: 22533568
14. Xie C, Zhong D and Chen X. Identification of the ortho-benzoquinone intermediate of 5-O-caffeoylquinic acid in vitro and in vivo: comparison of bioactivation under normal and pathological situations. Drug Metab Dispos. 2011, 40: 1628-1640. PMID: 22551521
15. 谢岑, 钟大放, 陈笑艳. 鉴定大鼠注射绿原酸体内的代谢产物. 药学学报 2011, 1: 88-95. PMID: 21465813
16. 谢岑, 钟大放, 陈笑艳. 液相色谱-串联质谱法检测反应性代谢物. 质谱学报 2011, 1: 1-12.
17. Xie C#, Yu K#, Zhong D, Yuan T, Ye F, Jarrell J, Millar A and Chen X. Investigation of isomeric transformations of chlorogenic acid in buffers and biological matrixes by ultraperformance liquid chromatography coupled with hybrid quadrupole/ion mobility/orthogonal acceleration time-of-flight mass spectrometry. J Agric Food Chem. 2011, 59: 11078-11087. PMID: 21942218
18. Xie C, Yang S, Zhong D, Dai X and Chen X. Simultaneous determination of dronedarone and its active metabolite debutyldronedarone in human plasma by liquid chromatography-tandem mass spectrometry: Application to a pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2011, 879: 3071-3075. PMID: 21937291
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