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1. Xu, Shilin#; Aguilar, Angelo#; Xu, Tianfeng#; Zheng, Ke#; Huang, Liyue; Stuckey, Jeanne; Chinnaswamy, Krishnapriya; Bernard, Denzil; Fernández‐Salas, Ester; Liu, Liu; Wang, Mi; McEachern, Donna; Przybranowski, Sally; Foster, Caroline; Wang, Shaomeng*, Design of the first‐in‐class, highly potent irreversible inhibitor targeting the menin‐MLL protein–protein interaction. Angewandte Chemie International Edition 2018, 57 (6), 1601-1605. (# Co-first author)
2. Aguilar, Angelo#; Zheng, Ke#; Xu, Tianfeng#; Xu, Shilin#; Huang, Liyue#; Fernandez-Salas, Ester; Liu, Liu; Bernard, Denzil; Harvey, Kaitlin P.; Foster, Caroline; McEachern, Donna; Stuckey, Jeanne; Chinnaswamy, Krishnapriya; Delproposto, James; Kampf, Jeff W.; Wang, Shaomeng*, Structure-Based Discovery of M-89 as a Highly Potent Inhibitor of the Menin-Mixed Lineage Leukemia (Menin-MLL) Protein–Protein Interaction. Journal of medicinal chemistry 2019, 62 (13), 6015-6034. (# Co-first author)
3. Xu, Shilin#; Mao, Liufeng#; Ding, Ping#; Zhuang, Xiaoxi; Zhou, Yang; Yu, Lei; Liu, Yingxue; Nie, Tao; Xu, Tingting; Xu, Yong; Liu, Jinsong; Smaill, Jeff; Ren, Xiaomei*; Wu, Donghai*; Ding, Ke*, 1-Benzyl-4-phenyl-1H-1,2,3-triazoles improve the transcriptional functions of estrogen-related receptor γ and promote the browning of white adipose. Bioorganic & Medicinal Chemistry 2015, 23 (13), 3751-3760. (# Co-first author)
4. Xu, Shilin; Xu, Tianfeng; Zhang, Lianwen; Zhang, Zhang; Luo, Jinfeng; Liu, Yingxue; Lu, Xiaoyun; Tu, Zhengchao; Ren, Xiaomei; Ding, Ke*, Design, Synthesis, and Biological Evaluation of 2-Oxo-3,4-dihydropyrimido[4,5-d]pyrimidinyl Derivatives as New Irreversible Epidermal Growth Factor Receptor Inhibitors with Improved Pharmacokinetic Properties. Journal of medicinal chemistry 2013, 56 (21), 8803-8813.
5. Xu, Shilin; Zhuang, Xiaoxi; Pan, Xiaofen; Zhang, Zhang; Duan, Lei; Liu, Yingxue; Zhang, Lianwen; Ren, Xiaomei*; Ding, Ke*, 1-Phenyl-4-benzoyl-1H-1,2,3-triazoles as Orally Bioavailable Transcriptional Function Suppressors of Estrogen-Related Receptor α. Journal of medicinal chemistry 2013, 56 (11), 4631-4640.
6. Xu, Shilin; Zhang, Lianwen; Chang, Shaohua; Luo, Jinfeng; Lu, Xiaoyun; Tu, Zhengchao; Liu, Yingxue; zhang, Zhang; Xu, Yong; Ren, Xiaomei; Ding, Ke*, Design, synthesis and biological evaluation of new molecules inhibiting epidermal growth factor receptor threonine790→ methionine790 mutant. MedChemComm 2012, 3 (9), 1155-1159.
7. Xu, Tianfeng#; Zhang, Lianwen#; Xu, Shilin; Yang, Chao-Yie; Luo, Jinfeng; Ding, Fang; Lu, Xiaoyun; Liu, Yingxue; Tu, Zhengchao; Li, Shiliang; Pei, Duanqing; Cai, Qian; Li, Honglin; Ren, Xiaomei; Wang, Shaomeng; Ding, Ke*, Pyrimido[4,5-d]pyrimidin-4(1H)-one Derivatives as Selective Inhibitors of EGFR Threonine790 to Methionine790 (T790M) Mutants. Angewandte Chemie International Edition 2013, 52 (32), 8387-8390.
8. Chang, Shaohua#; Zhang, Lianwen#; Xu, Shilin; Luo, Jinfeng; Lu, Xiaoyun; Zhang, Zhang; Xu, Tianfeng; Liu, Yingxue; Tu, Zhengchao; Xu, Yong; Ren, Xiaomei; Geng, Meiyu; Ding, Jian; Pei, Duanqing; Ding, Ke*, Design, Synthesis, and Biological Evaluation of Novel Conformationally Constrained Inhibitors Targeting Epidermal Growth Factor Receptor Threonine790 → Methionine790 Mutant. Journal of medicinal chemistry 2012, 55 (6), 2711-2723.
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