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Chao Wang, Wenxiang Zhang, Meng-Xin Yin, Lianxin Hu, Peixue Li, Jiajun Xu, Hongling Huang, Shimin Wang, Yi Lu, Wenqing Wu, Margaret S. Ho, Lin Li, Yun Zhao, and Lei Zhang* (2015) Suppressor of Deltex mediates Pez degradation and modulates Drosophila midgut homeostasis. Nature Communications, in press.
Jia Shen, Xiangpeng Sheng, ZeNan Chang, Qian Wu, Sheng Wang, Zongliang Xuan, Dan Li, Yalan Wu, Yongjia Shang, Xiangtao Kong, Long Yu, Lin Li, Kangchen Ruan, Hongyu Hu, Ying Huang, Lijian Hui, Dong Xie, Fudi Wang, and Ronggui Hu* (2014) Iron metabolism regulates p53 signaling through direct heme-p53 interaction and modulation of p53 localization, stability, and function. Cell Reports, 7, 1-14.
Zhengzhao Liu, Peng Chen, Hong Gao, Yu Gu, Jiao Yang, Hong Peng, Xingxing Xu, Haifeng Wang, Meiqiang Yang, Xiaoying Liu, Libin Fan, Shiyao Chen, Jian Zhou, Yihong Sun, Kangchen Ruan, Shuqun Cheng, Masaaki Komatsu, Eileen White, Lin Li, Hongbin Ji, Daniel Finley, Ronggui Hu* (2014) Ubiquitylation of autophagy receptor optineurin. Cancer Cell, 26, 106-120.
Xiaomin Song, Sheng Wang, and Lin Li* (2014) New insights into the regulation of Axin function in canonical Wnt signaling pathway. Protein & Cell, 5, 186-193
Ying-ying Jia, Fen Nie, Ai-ying Du, Zhang-cheng Chen, Yuan-bo Qin, Tao Huang, Xiao-min Song, and Lin Li* (2014) Thymine DNA glycosylase promotes transactivation of b-catenin/TCFs by cooperating with CBP. J. Mol. Cell Biol., 6, 231-239
Haofei Miao, Yingying Jia, Sichun Xie, Xin Wang, Jianfei Zhao, Youjun Chu, Zhilei Zhou, Zhubing Shi, Xiaomin Song*, and Lin Li* (2014) Structural insights into the C1q domain of Caprin-2 in canonical Wnt signaling. J. Biol. Chem., 289, 34104–34113
Cong Fei*, Xiaoli He, Sichun Xie, Haofei Miao, Zhilei Zhou, and Lin Li* (2014) Smurf1-mediated Axin ubiquitination requires Smurf1 C2 domain and is cell-cycle dependent. J. Biol. Chem., 289, 14170-14177
Sheng Wang, Junlin Yin, Duozhi Chen, Fen Nie, Xiaomin Song, Cong Fei, Haofei Miao, Changbin Jing, Wenjing Ma, Lei Wang, Sichun Xie, Chen Li, Rong Zeng, Weijun Pan, Xiaojiang Hao*, and Lin Li* (2013) Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction. Nature Chem. Biol., 9, 579-585.
Chun-Xiao Song, Keith E. Szulwach, Qing Dai, Ye Fu, Shi-Qing Mao, Li Lin, Craig Street, Yujing Li, Mickael Poidevin, Hao Wu, Juan Gao, Peng Liu, Lin Li, Guo-Liang Xu, Peng Jin, and Chuan He (2013) Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming. Cell, 153, 678-691.
Cong Fei, Zhenfei Li, Chen Li, Yuelei Chen, Zhangcheng Chen, Xiaoli He, Li Mao, Xin Wang, Rong Zeng, and Lin Li* (2013) Smurf1-mediated Lys29-linked non-proteolytic poly-ubiquitination of Axin negatively regulates Wnt/β-catenin signaling. Mol. Cell Biol., 33, 4095-4105.
Wei Wei, Meng Li, Jiyong Wang, Fen Nie and Lin Li* (2012) The E3 ubiquitin ligase ITCH negatively regulates canonical Wnt signaling by targeting dishevelled protein. Mol. Cell Biol., 32, 3903-3912.
Yu-Fei He, Bin-Zhong Li, Zheng Li, Peng Liu, Yang Wang, Qingyu Tang, Jianping Ding, Yingying Jia, Zhangcheng Chen, Lin Li, Yan Sun, Xiuxue Li, Qing Dai, Chun-Xiao Song, Kangling Zhang, Chuan He, and Guo-Liang Xu (2011) Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science, 333, 1303-1307.
Tao Huang, Zhihui Xie, Jiyong Wang, Meng Li, Naihe Jing, and Lin Li* (2011) Nuclear Factor of Activated T Cell (NFAT) Proteins repress canonical Wnt signaling via its interaction with dishevelled (Dvl) protein and participate in regulating neural progenitor cell proliferation and differentiation. J. Biol. Chem., 286, 37399-37405.
Wenwen Tang, Yong Zhang, Wenwen Xu, T. Kendall Harden, John Sondek, Le Sun, Lin Li, and Dianqing Wu* (2011) A PLCb/PI3Kg-GSK3 signaling pathway regulates cofilin phosphatase Slingshot2 and neutrophil polarization and chemotaxis. Dev. Cell, 21, 1038-1050.
Zhihui Xie, Yongfeng Chen, Zhenfei Li, Ge Bai, Yue Zhu, Rui Yan, Fangzhi Tan, Ye-Guang Chen, Francois Guillemot, Lin Li, and Naihe Jing (2011) Smad6 promotes neuronal differentiation in the intermediate zone of the dorsal neural tube by inhibition of the Wnt/b-catenin pathway. Proc. Natl. Acad. Sci. USA, 108, 12119-12124.
Zhenfei Li, Fen Nie, Sheng Wang, and Lin Li* (2011) Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation. Proc. Natl. Acad. Sci. USA, 108, 3116-3123.
Wei Wang, Haiyang Liu, Sheng Wang, Xiaojiang Hao*, and Lin Li* (2011) A diterpenoid derivative 15-oxospiramilactone inhibits Wnt/b-catenin signaling and colon cancer cell tumorigenesis. Cell Res., 21, 730-740.
Meng Li, He Wang, Tao Huang, Jiyong Wang, Yu Ding, Zhenfei Li, Jinkuo Zhang, and Lin Li* (2010) TAB2 scaffolds TAK1 and NLK in repressing canonical Wnt signaling. J. Biol. Chem., 285, 13397-13404.
Ning Deng, Yanger Ye, Wei Wang, and Lin Li* (2010) Dishevelled interacts with p65 and acts as a repressor of NF-kB-mediated transcription. Cell Res., 20, 1117-1127.
Bianhong Zhang, Meng Li, Liang Chen, Kai Yang, Yufei Shan, Lianhui Zhu, Shaogang Sun, and Lin Li*, and Chen Wang* (2009) The TAK1-JNK cascade is required for IRF3 function in the innate immune response. Cell Res., 19, 412-428.