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Lin CD, ZhangYH, Zhang K, Zheng YJ, Lu L, Chang HS, Yang H, Yang YR, Wan YY, Wang SH, Yuan MY, Yan ZJ, Zhang RG, He YN, Ge GX, Wu D, and Chen JF*. Fever Promotes T Lymphocyte Trafficking via a Thermal Sensory Pathway Involving Heat Shock Protein 90 and α4 Integrins. Immunity (2019), 50(1): 137-151.
Lin CD & Chen JF*. Regulation of immune cell trafficking by febrile temperatures, Int. J. Hyperthermia (2019), 36:sup1, 17-21. (invited review)
Guo J, Zhang Y, Li H, Chu H, Wang Q, Jiang S, Li Y, Shen H, Li G*, Chen JF*, Xu C* Intramembrane ionic protein-lipid interaction regulates integrin structure and function. PLoS Biol, (2018), 16(11): e2006525.
Wang SH, Wu C, Zhang CY, Zhong QL, Sun H, Cao WP, Ge GX, Li GH*, Zhang XF*, Chen JF*. Integrin α4β7 switches its ligand specificity via distinct conformer-specific activation. J Cell Biol. (2018), 217(8): 2799-2812.
Guo Q, Wang J, Xiao J, Wang L, Hu X, Yu W, Song G, Lou J*, Chen JF*. Heterogeneous mutation pattern in tumor tissue and circulating tumor DNA warrants parallel NGS panel testing. Mol Cancer (2018), 17(1):131.
Yan ZJ, Pan YD, Wang SH, Cheng MH, Kong HM, Sun CG, Hu K, Chen TL, Dong QR, Chen JF*. Static compression induces ECM remodeling and integrin α2β1 expression and signaling in a rat tail caudal intervertebral disc degeneration model. Spine (2017), 42(8): E448-E458.
Zhang YH, Pan YD, Lin CD, Zheng YJ, Sun H, Zhang HL, Wang JL, Yuan MY, Duan T*, Du QL*, Chen JF*. Bile acids evoke placental inflammation by activating Gpbar1/NF-κB pathway in intrahepatic cholestasis of pregnancy. J Mol Cell Biol. (2016),8(6):530-541.
Lu L, Lin CD, Yan ZJ, Wang S, Zhang YH, Wang SH, Wang JL, Liu C, Chen JF*. Kindlin-3 is essential for resting α4β1 integrin-mediated firm cell adhesion under shear flow conditions J Biol Chem. (2016), 291(19): 10363-71.
Zhang HL, Zheng YJ, Pan YD, Xie C, Sun H, Zhang YH, Yuan MY, Song BL, Chen JF*. Regulatory T-cell depletion in the gut caused by integrin β7 deficiency exacerbates DSS colitis by evoking aberrant innate immunity. Mucosal Immunol. (2015),9(2): 391-400.
Du QL, Pan YD, Zhang YH, Zhang HL, Zheng YJ, Lu L, Wang JL, Duan T*, Chen JF*.Placental gene-expression profiles of intrahepatic cholestasis of pregnancy reveal involvement of multiple molecular pathways in blood vessel formation and inflammation. BMC Med Genomics (2014), 7:24.
Sun H, Liu J, Zheng YJ, Pan YD, Zhang K, Chen JF*. Distinct chemokine signaling regulates integrin ligand specificity to dictate tissue-specific lymphocyte homing. Dev Cell (2014), 30(1): 61-70. (Cover Story).
Liu J, Fu T, Peng B, Sun H, Li GH*, Chen JF*. The Hydrophobic Contacts Between the Center of the βI Domain and the α1/α7 Helices are Crucial for the Low-Affinity State of Integrin α4β7. FEBS J. (2014), 281: 2519-26.
Zhang K, Pan YD, Qi JP, Yue J, Zhang MB, Xu CQ, Li GH*, Chen JF*. Disruption of disulfide-restriction at integrin knees induces activation and ligand-independent signaling of α4β7. J Cell Sci. (2013), 126:5030-41.
Yue J, Pan YD, Sun LF, Zhang K, Liu J, Lu L, Chen JF*. The unique disulfide bond-stabilized W1 β4-β1 loop in α4 β-propeller domain regulates integrin α4β7 affinity and signaling. J Biol Chem. (2013), 288(20): 14228-37.
Qi JP, Zhang K, Zhang Q, Sun Y, Fu T, Li GH, Chen JF*. Identification, characterization and epitope mapping of a human monoclonal antibody J19 that specifically recognizes the activated integrin α4β7. J Biol Chem. (2012), 287(19): 15749-59.
Yue J, Zhang K, Chen JF*. Role of integrins in regulating proteases to mediate extracellular matrix remodeling. Cancer Microenviron. (2012), 5(3):275-83. (invited review)
Zhang K, Chen JF*. The regulation of integrin function by divalent cations. Cell Adhes Migr. (2012), 6 (1): 1–10. (invited review)
Sun H, Wu YM, Qi JP, Pan YG, Ge GX, Chen JF*. The CC' and DE loops in Ig domains 1 and 2 of MAdCAM-1 play different roles in MAdCAM-1 binding to low- and high-affinity integrin α4β7. J Biol Chem. (2011), 286(14): 12086-92.
Pan YD, Zhang K, Qi JP, Yue J, Springer TA*, ChenJF*. Cation-π interaction regulates ligand-binding affinity and signaling of integrin α4β7. Proc. Natl. Acad. Sci. U. S. A. (2010), 107: 21388-93.
Chen JF, Yang W, Kim M, Carman CV, Springer TA. Regulation of Outside-In Signaling and Affinity by the β I domain of Integrin αLβ2. Proc. Natl. Acad. Sci. U. S. A. (2006), 103:13062-67.