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1. 李祥瑞主编，动物寄生虫病彩色图谱，第二版。中国农业出版社，北京,2011
年 10 月（国家出版基金项目现代农业科技专著大系）
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2013 年 12 月
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版社 高等教育电子音像出版社，北京，2016 年 10 月
4. Shuai Wang, Zhenchao Zhang, Yujian Wang, Javaid A. Gadahi, Lixin Xu,
Ruofeng Yan, Xiaokai Song and Xiangrui Li. Toxoplasma gondii Elongation
Factor1-Alpha (TgEF-1a) Is a Novel Vaccine Candidate Antigen against
Toxoplasmosis. Frontiers in Microbiology, 2017, 8: Article 168. doi:
10.3389/fmicb.2017.00168
5. Gadahi JA, Wang S, Bo G, Ehsan M, Yan R, Song X, Xu L, Li X. Proteomic
Analysis of the Excretory and Secretory Proteins of Haemonchus contortus
(HcESP) Binding to Goat PBMCs In Vivo Revealed Stage-Specific Binding
Profiles. PLoS One. 2016, 11(7): e0159796.
6. Javaid Ali Gadahi1, Baojie Li, Muhammad Ehsan1, Shuai Wang, Zhenchao
Zhang, Yujian Wang, Muhammad Waqqas Hasan, Ruofeng Yan, Xiaokai Song,
Lixin Xu and Xiangrui Li. Recombinant Haemonchus contortus 24 kDa
excretory/ secretory protein (rHcES-24) modulate the immune functions of goat
PBMCs in vitro. Oncotarget, 2016, doi: 10.18632/oncotarget.13487
7. Xiaokai Song, Zeyang Zhang, Chang Liu, Lixin Xu, Ruofeng Yan, Xiangrui Li.
Evaluation of the persistence, integration, histopathology and environmental
release of DNA vaccine encoding Eimeria tenella TA4 and chicken IL-2.
Veterinary Parasitology, 2016, 229: 22-30
8. ZhenChao Zhang, XinChao Liu, XinChao Yang, LianRui Liu, Shuai Wang,
MingMin Lu, Mohammad Ehsan, Javaid A. Gadahi, XiaoKai Song, LiXin Xu,
RuoFeng Yan & XiangRui Li. The Molecular Characterization and Immunity
Identification of Microneme 3 of Eimeria acervulina. Journal of Eukaryotic
Microbiology 2016, 0, 1–13
9. Javaid Ali Gadahi, Bu Yongqian, Muhammad Ehsan, Zhen Chao Zhang, Shuai
WANG, Ruo Feng Yan, Xiao Kai Song, Li Xin Xu and Xiang Rui Li.
Haemonchus contortus excretory and secretory proteins (HcESPs) suppress
functions of goat PBMCs in vitro. Oncotarget, 2016, 7(24): 35670–35679. doi:
10.18632/oncotarget.9589
10. Yan Li, Cheng Yuan, LiKun Wang, MingMin Lu, YuJian Wang, YuLing Wen,
RuoFeng Yan, LiXin Xu, XiaoKai Song and XiangRui Li. Transmembrane
protein 147 (TMEM147): another partner protein of Haemonchus contortus
galectin on the goat peripheral blood mononuclear cells (PBMC). Parasites &
Vectors, 2016, 9:355 DOI 10.1186/s13071-016-1640-0
11. Shuai Wang, YuJian Wang, XiaoNi Sun, ZhenChao Zhang, TingQi Liu, Javaid Ali
Gadahi, Ibrahim Adam Hassan, LiXin Xu, RuoFeng Yan, XiaoKai Song and
XiangRui Li. Protective immunity against acute toxoplasmosis in BALB/c mice
induced by a DNA vaccine encoding Toxoplasma gondii elongation factor
1-alpha. BMC Infectious Diseases (2015) 15:448 DOI
10.1186/s12879-015-1220-5
12. Shuai Wang, Yujian Wang, Xiaoni Sun, Zhenchao Zhang, Tingqi Liu, Javaid Ali
Gadahi, Lixin Xu, Ruofeng Yan, Xiaokai Song, Xiangrui Li. Protective immunity
against acute toxoplasmosis in BALB/c mice induced by a DNA vaccine
encoding Toxoplasma gondii 10 kDa excretory–secretory antigen (TgESA10).
Veterinary Parasitology, 2015, 214: 40–48 doi:10.1016/j.vetpar.2015.09.016
13. Jingwei Huang, Zhenchao Zhang, Menghui Li, Xiaokai Song, Ruofeng Yan,
Lixin Xu & Xiangrui Li. Immune protection of Microneme 7 (EmMIC7) against
Eimeria maxima challenge in chickens. Avian Pathology, 2015, 44, (5): 392–400
DOI: 10.1080/03079457.2015.1071780
14. Xiaokai Song, Lixin Xu, Ruofeng Yan, Xinmei Huanga, Xiangrui Li.
Construction of Eimeria tenella multi-epitope DNA vaccines and their protective
efficacies against experimental infection. Veterinary Immunology and
Immunopathology, 2015, 166:79-87
http://dx.doi.org/10.1016/j.vetimm.2015.05.005
15. Cheng Yuan, Hui Zhang, Wang Wang, Yan Li, RuoFeng Yan, LiXin Xu, XiaoKai
Song and XiangRui Li*.Transmembrane protein 63A is a partner protein of
Haemonchus contortus galectin in the regulation of goat peripheral blood
mononuclear cells. Parasites & Vectors 2015, 8:211
doi:10.1186/s13071-015-0816-3
16. 208. Xiaokai Song, Zhe Ren, Ruofeng Yan, Lixin Xu, Xiangrui Li*. Induction of
protective immunity against Eimeria tenella, Eimeria necatrix, Eimeria maxima
and Eimeria acervulina infections using multivalent epitope DNA vaccines.
Vaccine, 2015, 33: 2764–2770
17. Qing Xie, Julia Klesney-Tait, Kathy Keck, Corey Parlet, Nicholas Borcherding,
Ryan Kolb, Wei Li, Lorraine Tygrett, Thomas Waldschmidt, Alicia Olivier,
Songhai Chen, Guang-Hui Liu, Xiangrui Li1&, Weizhou Zhang. Characterization
of a novel mouse model with genetic deletion of CD177. Protein Cell, 2015,
6(2):117–126 DOI 10.1007/s13238-014-0109-1
18. ZhenChao Zhang, JingWei Huang, MengHui Li, YuXia Sui, Shuai Wang, LianRui
Liu, LiXin Xu, RuoFeng Yan, XiaoKai Song, XiangRui Li*. Identification and
molecular characterization of microneme 5 of Eimeria acervulina. PLOS ONE |
DOI:10.1371/journal.pone.0115411 December 22, 2014
19. I. A. HASSAN, S. WANG, L. XU, R. YAN, X. SONG & L. XIANGRUI.
Immunological response and protection of mice immunized with plasmid
encoding Toxoplasma gondii glycolytic enzyme malate dehydrogenase. Parasite
Immunology, 2014, 36, 674–683 DOI: 10.1111/pim.12146
20. Ruofeng Yan, Lixin Xu, Jingjing Wang, Xiaokai Song, Xiangrui Li. Cloning and
characterization of aldolase from parasitic nematode Haemonchus contortus.
Journal of Animal and Veterinary Advances, 2013,12(4):478-486
21. C. I. Muleke1, Yan Ruofeng2, Sun Yanming2, I. M. Osuga3, R. S. Shivairo1, Li
Xiangrui. Cellular Immune Response and Abomasum worm burden in Goats
Vaccinated with HC58cDNA Vaccine gainst H. contortus Infection. Advances in
Life Science and Technology, 2013，13：26-33
22. Meng Zhang1, Zhen Yang1, Shuai Wang, LongFei Tao, LiXin Xu, RuoFeng Yan,
XiaoKai Song, XiangRui Li. Detection of Toxoplasma gondii in shellfish and fish
in parts of China. Veterinary Parasitology, 2014, 200, 1-2: 85-89
23. Shuai Wang, GuangWei Zhao, Wang Wang, Qing Xie, Meng Zhang, Cheng Yuan,
Ibrahim Adam Hassan, XinChao Liu, LiXin Xu, RuoFeng Yan, XiaoKai Song,
and XiangRui Li. Pathogenicity of two Toxoplasma gondii strains in chickens of
different ages infected via intraperitoneal injection. Avian Pathology, 2014, 43, 1:
1–5
24. Wang Wang, Cheng Yuan, Shuai Wang, XiaoKai Song, LiXin Xu, RuoFeng Yan,
I.A. Hasson, XiangRui Li. Transcriptional and proteomic analysis reveal
recombinant galectins of Haemonchus contortus down-regulated functions of
goat PBMC and modulation of several signaling cascades in vitro. Journal of
Proteomics, 2014, 98, 26:123–137
25. Tran Duc Hoan, Doan Thi Thao , Javaid Ali Gadahi, Xiaokai Song, Lixin Xu,
Ruofeng Yan, Xiangrui Li. Analysis of humoral immune response and cytokines
in chickens vaccinated with Eimeria brunetti apical membrane
antigen-1(EbAMA1) DNA vaccine. Experimental Parasitology. 2014,144: 65–72
26. Wang Wang, Shuai Wang, Hui Zhang, Cheng Yuan, RuoFeng Yan, XiaoKai Song,
LiXin Xu and XiangRui Li. Galectin Hco-gal-m from Haemonchus contortus
modulates goat monocytes and T cell function in different patterns. Parasites &
Vectors 2014, 7:342 http://www.parasitesandvectors.com/content/7/1/342
27. Ruofeng Yan, Jingjing Wang, Lixin Xu, Xiaokai Song and Xiangrui Li*. DNA
vaccine encoding Haemonchus contortus Actin induces partial protection in Goats.
Acta Parasitologica, 2014, 59(4), 698–709 DOI: 10.2478/s11686-014-0298-z
28. Ibrahim A Hassan, Shuai Wang, LiXin Xu, RuoFeng Yan, XiaoKai Song and
Xiangrui Li. DNA vaccination with a gene encoding Toxoplasma gondii
Deoxyribose Phosphate Aldolase (TgDPA) induces partial protective immunity
against lethal challenge in mice. Parasites & Vectors 2014, 7:431
http://www.parasitesandvectors.com/content/7/1/431
29. Yanhui Han, Zhiqiang Fu, Yang Hong, Min Zhang, Hongxiao Han, Ke Lu,
Jianmei Yang, Xiangrui Li†, and Jiaojiao Lin*. Inhibitory Effects and Analysis of
RNA Interference on Thioredoxin Glutathione Reductase Expression in
Schistosoma japonicum. J. Parasitol., 2014,100(4): 463–469
30. Ibrahim A. Hassan, Shuai Wang, LiXin Xu, RuoFeng Yan, XiaoKai Song,
XiangRui Li. Immunoglobulin and cytokine changes induced following
immunization with a DNA vaccine encoding Toxoplasma gondii
selenium-dependent glutathione reductase protein. Experimental Parasitology,
2014, 146: 1–10
31. Tang F, Xu L, Yan R, Song X, Li X. A DNA vaccine co-expressing Trichinella
spiralis MIF and MCD-1 with murine ubiquitin induces partial protective
immunity in mice. J Helminthol. 2013, 87:24-33
doi:10.1017/S0022149X1100068X
32. Hongyan Song, Baofeng Qiu, Ruofeng Yan, Lixin Xu, Xiaokai Song, Xiangrui
Li . The protective efficacy of chimeric SO7/IL-2 DNA vaccine against
coccidiosis in chickens. Research in Veterinary Science. 2013, 94: 562–567.
http://dx.doi.org/10.1016/j.rvsc.2012.11.006
33. Tao Lin, Xiangrui Li, Huochun Yao, Zuhang Wei, Runxia Liu, Yu Deng, Shaolun
Zhai, Wenliang Li, Lichang Sun, Jinxue Long, Hongbiao Zhang, Jiaqi Lu and
Shishan Yuan. Phylogenetic Diversity of Classical Swine Fever Virus(CSFV)
Field Isolates from Outbreaks in China Between 2008 and 2011. Asian Journal of
Animal and Veterinary Advances, 2013, 8, (3):449-460 DOI:
10.3923/ajava.2013
34. Ruofeng Yan, Wei Sun, Xiaokai Song, Lixin Xu, Xiangrui Li.Vaccination of goats
with DNA vaccine encoding Dim-1 induced partial protection against
Haemonchus contortus: A preliminary experimental study. Res. Vet. Sci. 2013,
95:189–199 http://dx.doi.org/10.1016/j.rvsc.2013.02.020
35. F. Tang, L. Xu, R. Yan, X. Song and X. Li. Evaluation of the immune response
induced by DNA vaccines expressing MIF and MCD1genes of Trichinella spiralis
in BALB/c mice. J Helminthol. 2012, 86:430–439 DOI:
10.1017/S0022149X11000654,
36. GuangWei Zhao, RuoFeng Yan, Charles I. Muleke YanMing Sun, LiXin Xu,
XiangRui Li, Vaccination of goats with DNA vaccines encoding H11 and IL-2
induces partial protection against Haemonchus contortus infection. The
Veterinary Journal, 2012, 191: 94–100
37. Kaikai Han, Lixin Xu, Ruofeng Yan, Xiaokai Song, Xiangrui Li. Molecular
cloning, expression and characterization of enolase from adult Haemonchus
contortus. Research in Veterinary Science, 2012, 92: 259–265
38. GuangWei Zhao, Bo Shen, Qing Xie, Li Xin Xu, Ruo Feng Yan, Xiao Kai Song,
I.A. Hassan, Xiang Rui Li ∗Detection of Toxoplasma gondii in free-range
chickens in China based on circulating antigens and antibodies. Veterinary
Parasitology, 2012, 18, 572–577 doi:10.1016/j.vetpar.2011.10.031
39. Wei Sun, Xiaokai Song, Ruofeng Yan, Lixin Xu, Xiangrui Li. Cloning and
characterization of a selenium-independent glutathione peroxidase (HC29) from
adult Haemonchus contortus. J Vet Sci, 2012, 13(1), 49-58
40. Han K, Xu L, Yan R, Song X, Li X. Vaccination of goats with
glyceraldehyde-3-phosphate dehydrogenase DNA vaccine induced partial
protection against Haemonchus contortus. Vet Immunol Immunopathol. 2012,
149: 177-185 http://dx.doi.org/10.1016/j.vetimm.2012.06.016
41. Zhu Z, Fu Z, Zhang M, Han Y, Hong Y, Li D, Zhao Z, Shi Y, Li X, Lin J.
Protective efficacy evaluation induced by recombinant protein LHD-Sj23-GST of
Schistosoma japonicum emulsified with three different adjuvants. Parasite
Immunol.2012, 34(6):341-344. doi: 10.1111/j.1365-3024.2012.01357.x.
42. Tao Lin • Xiangrui Li • Huochun Yao • Zuzhang Wei • Feifei Tan •Runxia Liu •
Lichang Sun • Rong Zhang • Wenliang Li • Jiaqi Lu •Guangzhi Tong • Shishan
Yuan. Use of reverse genetics to develop a novel marker porcine reproductive and
respiratory syndrome virus. Virus Genes, 2012, 45:548–555 DOI
10.1007/s11262-012-0812-z
43. ZHAO Guang-wei, SHEN Bo, XIE Qing, XU Li-xin, YAN Ruo-feng, SONG
Xiao-kai, Hassan Ibrahim Adam and LI Xiang-rui. Isolation and Molecular
Characterization of Toxoplasma gondii from Chickens in China. Journal of
Integrative Agriculture, 2012, 11(8): 1347-1353
44. Huili Zhu, Ruofeng Yan, Song Wang, Xiaokai Song, Lixin Xu, Xiangrui Li.
Identification and molecular characterization of a novel antigen of Eimeria
acervulina. Molecular and Biochemical Parasitology, 2012, 186: 21-28
http://dx.doi.org/10.1016/j.molbiopara.2012.09.002
45. HUILI ZHU, LIXIN XU, RUOFENG YAN, XIAOKAI SONG, FANG TANG,
SONG WANG and XIANGRUI LI. Identification and characterization of a cDNA
clone-encoding antigen of Eimeria acervulina. Parasitology, 2012, 139:
1711–1719. doi:10.1017/S0031182012001163
46. Muhammad Ali A. Shah, Xiaokai Song, Lixin Xu, Ruofeng Yan, Xiangrui Li *,
Construction of DNA vaccines encoding Eimeria acervulina cSZ-2 with chicken
IL-2 and IFN-c and their efficacy against poultry coccidiosis. Research in
Veterinary Science, 2011, 90: 72–77
47. Geriletu, Lixin Xu, Xurihua, Xiangrui Li, Vaccination of chickens with DNA
vaccine expressing Eimeria tenella MZ5-7 against coccidiosis. Veterinary
Parasitology, 2011, 177: 6–12
48. Liu Wen-xing,1,2 Hu Sen,2 Qiao Zu-jian,2 Chen Wei-ye,2 Liu Lin-tao,2 Wang
Fang-kun,2 Hua Rong-hong,2 Bu ZHi-gao,2∗ and Li Xiang-rui1∗, Expression,
purification, and improved antigenic specificity of a truncated recombinant bp26
protein of Brucella melitensis M5-90: a potential antigen for differential
serodiagnosis of brucellosis in ship and goats. Biotechnology and Applied
Biochemistry, 2011,58(1): 32-38
49. K. Han, L. Xu, R. Yan, X. Song and X. Li*. Cloning, expression and
characterization of NAD1-dependent glyceraldehyde-3-phosphate dehydrogenase
of adult Haemonchus contortus. Journal of Helminthology, 2011, 85: 421–429
50. Wei Sun, Xiaokai Song, Ruofeng Yan, Lixin Xu, Xiangrui Li ∗. Vaccination of
goats with a glutathione peroxidase DNA vaccine induced partial protection
against Haemonchus contortus infection. Veterinary Parasitology, 2011, 182:
239-247
51. Yang Hong, Jinbiao Peng, Weibin Jiang, Zhiqiang Fu , Jinming Liu , Yaojun Shi,
Xiangrui Li *, Jiaojiao Lin*. Proteomic analysis of Schistosoma japonicum
schistosomulum proteins that are differentially expressed among hosts differing
in their susceptibility to the infection. Molecular & Cellular Proteomics，2011， 10.8 10.1074/mcp.M110.006098–1
52. Mohammad AliA. Shah, Roufeng Yan, Lixin Xu, Xiaokai Song,Xiangrui Li *. A
recombinant DNA vaccine encoding Eimeria acervulina cSZ-2 induces immunity
against experimental E.tenella infection. Veterinary Parasitology. 2010,
169,185–189
53. Shah Mohammed Ali A, Lixin Xu, Roufeng yan, Xiaokai Song, Xiangrui Li*.
Cross immunity of DNA vaccine pVAX1-cSZ2-IL-2 to Eimeria tenella, E.
necatrix and E. maxima. Experimental parasitology, 2010,124,330-333
54. Daosheng Yi, Lixin Xu, Ruofeng Yan, Xiangrui Li*, Haemonchus contortus:
Cloning and characterization of serpin. Experimental Parasitology, 2010, 125,
363–370
55. Feng Bin Yan, Li Xin Xu, Li Heng Liu, Ruo Feng Yan, Xiao Kai Song, Xiang Rui
Li * Immunoproteomic analysis of whole proteins from male and female adult
Haemonchus contortus. The Veterinary Journal, 2010,18: 174-179
56. Hongyan Song, Ruofeng Yan, Lixin Xu, Xiaokai Song, Mohammed Ali A. Shah,
Huili Zhu, Xiangrui Li*. Efficacy of DNA vaccines carrying Eimeria acervulina
lactate dehydrogenase antigen gene against coccidiosis. Experimental
Parasitology, 2010, 126, 224–231
57. Muhammad AliA. Shah & Xiaokai Song & Lixin Xu Roufeng Yan & HongyanS
ong & Zhang Ruirui & Lei Chengyu & Xiangrui Li. TheDNA-induced protective
immunity with chicken interferon gamma against poultry coccidiosis. Parasitol
Res, 2010, 107:747–750
58. Yang Hong, Hongxiao Han, Jinbiao Peng, Ye Li, Yaojun Shi, Zhiqiang Fu,
Jinming Liu, Jiaojiao Lin, Xiangrui Li. Schistosoma japonicum: Cloning,
expression and characterization of a gene encoding the a5-subunit of the
proteasome. Experimental Parasitology, 2010, 126:517-525
59. Hongyan Song, Xiaokai Song, Lixin Xu, Ruofeng Yan, Muhammed Ali A Shah,
Xiangrui Li*, Changes of cytokines and IgG antibody in chickens vaccinated
with DNA vaccines encoding Eimeria acervulina lactate dehydrogenase. Vet
Parasitol, 2010,173: 219-227
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