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个人简介

教育背景 2008-06--2008-10 荷兰阿姆斯特丹大学医学中心 高级访问学者 1998-02--1999-01 美国UCLA大学风湿病学中心 访问学者 1988-09--1991-07 上海交通大学医学院 硕士 1983-09--1988-07 上海交通大学医学院 学士 工作简历 2008-03--今 上海交通大学医学院附属仁济医院 主任医师,教授,所长 2003-11--2008-02 上海交通大学医学院附属仁济医院 主任医师,教授,副所长 2003-01--今 健康科学研究所 研究员,PI 1999-01--2003-11 上海交通大学医学院附属仁济医院,上海市风湿病学研究所 副主任医师,副教授,副所长 1993-12--1999-01 上海交通大学医学院附属仁济医院 主治医师 1991-08--1993-11 上海交通大学医学院附属仁济医院 住院医师

研究领域

系统性红斑狼疮等自身免疫性疾病的发病机理研究

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Let-7/miR-98 regulate Fas and Fas-mediated apoptosis, Genes Immun . ,2011,通讯作者 Single-nucleotide polymorphisms and haplotype of CYP2E1 gene associated with systemic lupus erythematosus in Chinese population,Arthritis Res Ther. ,2011,通讯作者 Interferon-α Priming Promotes Lipid Uptake and Macrophage-Derived Foam Cell Formation: A Novel Link between Interferon-α and Atherosclerosis in Lupus,Arthritis Rheum.,2011,通讯作者 A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus,PLoS Genet.,2011,通讯作者 Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus,PLoS Genet. ,2010,第2作者 MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1,J Immunol.,2010,通讯作者 Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus,Proc Natl Acad Sci U S A. ,2010,通讯作者 miR-155 and its star-form partner miR-155* cooperatively regulate type I interferon production by human plasmacytoid dendritic cells,blood,2010,通讯作者 MicroRNA-125a contributes to elevated inflammatory chemokine RANTES via targeting KLF13 in systemic lupus erythematosus,Arthritis Rheum.,2010,通讯作者 MicroRNA-146a Contributes to Abnormal Activation of the Type I Interferon Pathway in Human Lupus by Targeting the Key Signaling Proteins,Arthritis Rheum.,2009,通讯作者 Association of elevated transcript levels of interferon-inducible chemokines with disease activity and organ damage in systemic lupus erythematosus patients,Arthritis Res Ther. ,2008,通讯作者 Interferon-induced protein IFIT4 is associated with systemic lupus erythematosus and promotes differentiation of monocytes into dendritic cell-like cells,Arthritis Res Ther. ,2008,通讯作者 Increased expression of the type I interferon-inducible gene, lymphocyte antigen 6 complex locus E, in peripheral blood cells is predictive of lupus activity in a large cohort of Chinese lupus patients,lupus,2008,通讯作者 Dysfunctional CD4+,CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-alpha-producing antigen-presenting cells,Arthritis Rheum. ,2008,通讯作者 Genomic view of IFN-alpha response in pre-autoimmune NZB/W and MRL/lpr mice ,Genes Immun.,2007,通讯作者 Protein interaction for an interferon-inducible systemic lupus associated gene,IFIT1,Rheumatology (Oxford),2003,通讯作者

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