唐宏 - 中国科学院物理研究所 -

个人简介

南京大学生物化学系学士美国Rutgers大学及Robert Wood Johnson医学院分子遗传与微生物学博士美国麻省理工学院博士后美国Dupont Pharmaceutical Company 高级研究员中国科学院微生物研究所研究员，博导中科院生物物理所研究员。感染与免疫研究中心主任。现任中国免疫学会常务理事，中国生物物理学会理事，《微生物学报》、《中国免疫学杂志》、《肿瘤生物治疗》和《生物化学与生物物理进展》编委

研究领域

主要研究冠状病毒、肝炎病毒感染的天然免疫应答的分子机制，以及T细胞对炎性反应的调控机制

近期论文

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Zhao J, Kim KD, Yang X, Auh S, and Fu YX*,Tang*, H. (2008) Hyper innate responses in neonates lead to increased morbidity and mortality after infection. Proc Natl Acad Sci U S A. 105(21):7528-33 (*co-correspondence). Pan L, Chen S, Weng C, Call G, Zhu D, and Tang, H., Zhang N and Xie T (2007) Stem cell aging is controlled both intrinsically and extrinsically in the drosophila ovary. Cell Stem Cell 1:458-469. Chen J, Chen L, Wang G, and Tang H. Cholesterol-Dependent and -Independent CD40 Internalization and Signaling Activation in Cardiovascular Endothelial Cells, Arterioscler Thromb Vasc Biol. 2007, 27(9):2005-13. Kim KD, Zhao J, Auh S, Yang X, Du P, Tang H, Fu YX. Adaptive immune cells temper initial innate responses, Nat Med, 2007:1248-1252 Qin X and Tang H. Differential regulation of chromatin structure of the murine 3?IgH enhancer and IgG2b germline promoter in response to lipopolysaccharide and CD40 signaling. Mol Immunol, 2006, 43:1211-20. Weng C, Li Y, Xu D, Shi Y, Tang H (2005) Specific cleavage of Mcl-1 by caspase-3 in TRAIL- induced apoptosis in Jurkat leukemia T cells. J Biol Chem., 280:(11) 10491–10500. Kang X., Xu Y., Wu X., Liang Y., Wang C., Guo J. Wang Y., Chen M., Wu D., Wang Y., Bi S., Qiu Y., Lu P., Cheng J., Xiao B., Hu L., Gao X., Liu J., Wang Y., Song Y., Zhang L., Suo F., Chen T., Huang Z., Zhao Y., Lu H., Pan C. and Tang H (2005) Proteomic Fingerprints for Potential Application to Early Diagnosis of Severe Acute Respiratory Syndrome. Clin Chem 51(1): 56-64. Tang H and Sharp PA (1999) Transcriptional regulation of the murine 3' IgH enhancer by Oct-2. Immunity 11, 517-26.