Ding, Changhai - University of Tasmania - Menzies Institute for Medical Research

个人简介

Prof Changhai Ding is an ARC Future Fellow at the Menzies Institute for Medical Research. He is a member of Global Engagement Committee, UTAS; Associate Director, Menzies Institute for Medical Research; and Director, Arthritis Research Institute of Anhui Medical University. He has received >10 awards including a Future Fellowship by Australian Research Council (Level 2, 2012-2015), Career Development Award by NHMRC (Level 2, 2008-2011), 'Ten of the Best Research Projects 2013' by NHMRC, Servier Young Investigator Prize by Servier Research Institute (France) and Rising Star by UTAS. He is interested in epidemiological and clinical investigation of osteoarthritis and osteoporosis. Biography Changhai Ding is a Professor at University of Tasmanian, Honorary Professor at the University of Sydney, and an Adjunct Associate Professor at Monash University. He is currently an Adjunct Professor at Anhui Medical University, a Guest Professor at Xi'an Jiaotong University and a Visiting Professor at Shanghai University of TCM, China. He joined the Menzies Institute for Medical Research in 2000, had been a Senior Research Fellow during 2006 - 2009, and an Associate Professor during 2010-2013, and has been a Professor since 2014. Before joining UTAS, Changhai was a Professor (1999-2000), an Associate Professor (1995-1998) and an Associate Lecturer (1993-1995) at Anhui Medical University, China.

研究领域

His research interests include understanding the roles of inflammatory biomarkers, adipokines and vitamin D in knee osteoarthritis and osteoporosis. His findings suggest that inflammatory and metabolic mechanisms are very important to maintain knee cartilage health suggesting aiming at these factors may prevent and/or treat knee osteoarthritis.

近期论文

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Cao P, Li Y, Tang Y, Ding C, Hunter DJ, 'Pharmacotherapy for knee osteoarthritis: current and emerging therapies', Expert Opinion on Pharmacotherapy pp. 1-13. ISSN 1465-6566 (2020) [Refereed Article] Ding C, Cicuttini F, Scott F, Cooley HM, Jones G, 'Knee structural alteration and body mass index: a cross-sectional study', Obesity Research ISSN 1071-7323 (In Press) [Refereed Article] Wang K, Ding C, Hannon MJ, Chen Z, Kwoh CK, et al., 'Quantitative signal intensity alteration in infrapatellar fat pad predicts incident radiographic osteoarthritis: the Osteoarthritis Initiative', Arthritis Care & Research, 71, (1) pp. 30-38. ISSN 2151-464X (2019) [Refereed Article] Wu J, Zhu Z, Yu Q, Ding C, 'Tyrosine kinase inhibitors for the treatment of rheumatoid arthritis: phase I to II clinical trials', Expert Opinion on Investigational Drugs, 28, (12) pp. 1113-1123. ISSN 1354-3784 (2019) [Refereed Article] Zhu Z, Aitken D, Cicuttini F, Jones G, Ding C, 'Ambulatory activity interacts with common risk factors for osteoarthritis to modify increases in MRI-detected osteophytes', Osteoarthritis and Cartilage, 27, (4) pp. 650-658. ISSN 1063-4584 (2019) [Refereed Article] Huang Z, Ding C, Li T, Yu SP, 'Current status and future prospects for disease modification in osteoarthritis', Rheumatology, 57 pp. iv108-iv123. ISSN 1462-0324 (2018) [Refereed Article] Mattap SM, Aitken D, Wills K, Halliday A, Ding C, et al., 'Patellar tendon enthesis abnormalities and their association with knee pain and structural abnormalities in older adults', Osteoarthritis and Cartilage, 27, (3) pp. 449-458. ISSN 1063-4584 (2018) [Refereed Article] Mattap SM, Aitken D, Wills K, Laslett L, Ding C, et al., 'How do MRI-detected subchondral bone marrow lesions (BMLs) on two different MRI sequences correlate with clinically important outcomes?', Calcified Tissue International, 103, (2) pp. 131-143. ISSN 0171-967X (2018) [Refereed Article] Wang K, Ding C, Hannon MJ, Chen Z, Kwoh CK, et al., 'Signal intensity alteration within infrapatellar fat pad predicts knee replacement within 5 years: data from the Osteoarthritis Initiative', Osteoarthritis and Cartilage, 26, (10) pp. 1345-1350. ISSN 1063-4584 (2018) [Refereed Article] Wang X, Hunter DJ, Jin X, Ding C, 'The importance of synovial inflammation in osteoarthritis: current evidence from imaging assessments and clinical trials', Osteoarthritis and Cartilage, 26, (2) pp. 165-174. ISSN 1063-4584 (2018) [Refereed Article] Zhu Z, Ding C, Han W, Zheng S, Winzenberg T, et al., 'MRI-detected osteophytes of the knee: natural history and structural correlates of change', Arthritis Research & Therapy, 20, (1) Article 237. ISSN 1478-6362 (2018) [Refereed Article] Antony B, Ding C, 'Vitamin D and osteoarthritis: disparity between observational studies and clinical trials', International Journal of Rheumatic Diseases, 20, (6) pp. 671-674. ISSN 1756-1841 (2017) [Letter or Note in Journal] Han W, Fan S, Bai X, Ding C, 'Strontium ranelate, a promising disease modifying osteoarthritis drug', Expert Opinion on Investigational Drugs, 26, (3) pp. 375-380. ISSN 1354-3784 (2017) [Refereed Article] Ahedi HG, Aitken DA, Blizzard LC, Ding CH, Cicuttini FM, et al., 'Correlates of Hip Cartilage Defects: A Cross-sectional Study in Older Adults', Journal of Rheumatology, 43, (7) pp. 1406-1412. ISSN 0315-162X (2016) [Refereed Article] Antony B, Jones G, Jin X, Ding C, 'Do early life factors affect the development of knee osteoarthritis in later life: a narrative review', Arthritis Research & Therapy, 18, (1) Article 202. ISSN 1478-6362 (2016) [Refereed Article] Jin X, Ding C, Wang X, Antony B, Laslett LL, et al., 'Longitudinal associations between adiposity and change in knee pain: Tasmanian older adult cohort study', Seminars in Arthritis and Rheumatism, 45, (5) pp. 564-569. ISSN 0049-0172 (2016) [Refereed Article] Khan HI, Aitken D, Ding C, Blizzard L, Pelletier JP, et al., 'Natural history and clinical significance of meniscal tears over 8 years in a midlife cohort', BMC Musculoskeletal Disorders, 17 Article 4. ISSN 1471-2474 (2016) [Refereed Article] Khan HI, Chou L, Aitken D, McBride A, Ding C, et al., 'Correlation between changes in global knee structures assessed on Magnetic Resonance Imaging and radiographic osteoarthritis changes over 10 years in a mid-life cohort', Arthritis Care & Research, 68, (7) pp. 958-964. ISSN 2151-4658 (2016) [Refereed Article] McBride A, Khan HI, Aitken D, Chou L, Ding C, et al., 'Does cartilage volume measurement or radiographic osteoarthritis at baseline independently predict ten-year cartilage volume loss?', BMC Musculoskeletal Disorders, 17 Article 54. ISSN 1471-2474 (2016) [Refereed Article] Pan F, Ding C, Winzenberg T, Khan H, Martel-Pelletier J, et al., 'The offspring of people with a total knee replacement for severe primary knee osteoarthritis have a higher risk of worsening knee pain over 8 years', ARD Online, 75, (2) pp. 368-373. ISSN 1468-2060 (2016) [Refereed Article]