刘德华 - 清华大学 - 化学工程系

个人简介

主要研究领域为生物质综合利用的生物炼制技术，侧重于微生物发酵、酶催化转化及产品纯化工艺优化、设备研发及过程集成。主持完成国家“863”重点项目——1,3-丙二醇的生物炼制，建成万吨级生产装置两套，填补国内空白；主持研发酶法生物柴油技术及其产业化，建成全球首套酶法生物柴油工业化装置，该技术已分别在巴西、马来西亚实现工业化示范。已申请60多项发明专利，获中国专利授权50多项，并有多项核心专利已获美国、欧盟、加拿大、澳大利亚、日本、俄罗斯、新加坡、巴西、印度等二十多国授权，发表SCI收录论文近200篇。主持完成的“生物法耦合生产生物柴油与1,3-丙二醇”项目先后荣获中国石油化工联合会科技进步一等奖(2006)、中国技术市场金桥奖(2007)、日内瓦国际发明博览会金奖（2015）、联合国工业发展组织全球可再生能源领域最具投资价值领先技术“蓝天奖”（2016）、中国石油化工联合会“技术发明一等奖”（2016）。荣获“全国化工优秀科技工作者”（2010）、享受国务院政府特殊津贴（2016）。教育与工作经历 1981~1986 清华大学化学与化学工程系本科 1986~1991 清华大学化学工程系博士 1991~1993 中科院化工冶金研究所博士后 1993~1999 中科院化工冶金研究所副研究员、研究员 1994.10-1995.7 美国普度大学访问学者 1999~至今清华大学化学工程系应化所研究员，所长 2010-至今清华大学中国-巴西气候变化与能源技术创新研究中心主任主要学术任职 2006年~至今中国化工学会会员 2016年~至今全国变性燃料乙醇和燃料乙醇标准化技术委员会委员 2016年~至今生物质能可持续准则国际标准国内技术对口专家组专家 2017年~至今中国可再生能源学会生物质能委员会常务委员学术荣誉与奖励 2018年，全球绿色低碳领域最具投资价值的领先技术蓝天奖 2016年，酶促非食用油脂制备生物柴油技术开发与集成发大中国石油和化学工业协会技术发明奖一等奖 2016年，全球可再生能源领域最具投资价值的领先技术蓝天奖 2015年，酶促油脂制备生物柴油先进技术，日内瓦国际专利发明展金奖 2011年，生物工程学报优秀特邀编辑奖，《生物工程学报》 2010年，全国化工优秀科技工作者，中国石油和化学工业协会

研究领域

生物能源；生物炼制；生物反应器设计与优化；发酵工程；生物制造过程优化与集成

近期论文

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Wu, W., Zhang, Y., Liu, D. and Chen, Z., 2019. Efficient mining of natural NADH-utilizing dehydrogenases enables systematic cofactor engineering of lysine synthesis pathway of Corynebacterium glutamicum. Metabolic Engineering, 52, pp. 77-86. Kuan, D., Dai, L., Liu, D., Liu, H. and Du, W., 2019. Efficient Biodiesel Conversion from Microalgae Oil of Schizochytrium sp. Catalysts, 9(4), pp. Kuan, D., Dai, L., Liu, D., Du, W. and Liu, H., 2019. A novel clean process for the combined production of fatty acid ethyl esters (FAEEs) and the ethyl ester of polyunsaturated fatty acids (PUFAs) from microalgae oils. Renewable Energy, 143, pp. 772-778. Zhao, X., Wen, J., Chen, H. and Liu, D., 2018. The fate of lignin during atmospheric acetic acid pretreatment of sugarcane bagasse and the impacts on cellulose enzymatic hydrolyzability for bioethanol production. Renewable Energy, 128, pp. 200-209. Sajid, M., Zhao, X. and Liu, D., 2018. Production of 2,5-furandicarboxylic acid (FDCA) from 5-hydroxymethylfurfural (HMF): recent progress focusing on the chemical-catalytic routes. Green Chemistry, 20(24), pp. 5427-5453. Hu, Y., Dai, L., Liu, D., Du, W. and Wang, Y., 2018. Progress & prospect of metal-organic frameworks (MOFs) for enzyme immobilization (enzyme/MOFs). Renewable & Sustainable Energy Reviews, 91, pp. 793-801. Zhao, X., Li, S., Wu, R. and Liu, D., 2017. Organosolv fractionating pre-treatment of lignocellulosic biomass for efficient enzymatic saccharification: chemistry, kinetics, and substrate structures. Biofuels Bioproducts & Biorefining-Biofpr, 11(3), pp. 567-590. Chen, Z. and Liu, D., 2016. Toward glycerol biorefinery: metabolic engineering for the production of biofuels and chemicals from glycerol. Biotechnology for Biofuels, 9, pp. Chen, Z., Huang, J., Wu, Y. and Liu, D., 2016. Metabolic engineering of Corynebacterium glutamicum for the de novo production of ethylene glycol from glucose. Metabolic Engineering, 33, pp. 12-18. Chen, H., Zhao, X. and Liu, D., 2016. Relative Significance of the Negative Impacts of Hemicelluloses on Enzymatic Cellulose Hydrolysis Is Dependent on Lignin Content: Evidence from Substrate Structural Features and Protein Adsorption. Acs Sustainable Chemistry & Engineering, 4(12), pp. 6668-6679. Akimkulova, A., Zhou, Y., Zhao, X. and Liu, D., 2016. Improving the enzymatic hydrolysis of dilute acid pretreated wheat straw by metal ion blocking of non-productive cellulase adsorption on lignin. Bioresource Technology, 208, pp. 110-116. Zhou, Y., Chen, H., Qi, F., Zhao, X. and Liu, D., 2015. Non-ionic surfactants do not consistently improve the enzymatic hydrolysis of pure cellulose. Bioresource Technology, 182, pp. 136-143. Li, Y., Du, W. and Liu, D., 2015. Efficient biodiesel production from phospholipids-containing oil: Synchronous catalysis with phospholipase and lipase. Biochemical Engineering Journal, 94, pp. 45-49. Chen, H., Zhao, J., Hu, T., Zhao, X. and Liu, D., 2015. A comparison of several organosolv pretreatments for improving the enzymatic hydrolysis of wheat straw: Substrate digestibility, fermentability and structural features. Applied Energy, 150, pp. 224-232. Zhao, X., Morikawa, Y., Qi, F., Zeng, J. and Liu, D., 2014. A novel kinetic model for polysaccharide dissolution during atmospheric acetic acid pretreatment of sugarcane bagasse. Bioresource Technology, 151, pp. 128-136. Morikawa, Y., Zhao, X. and Liu, D., 2014. Biological co-production of ethanol and biodiesel from wheat straw: a case of dilute acid pretreatment. Rsc Advances, 4(71), pp. 37878-37888. Zhao, X., Zhang, L. and Liu, D., 2012. Biomass recalcitrance. Part II: Fundamentals of different pre-treatments to increase the enzymatic digestibility of lignocellulose. Biofuels Bioproducts & Biorefining-Biofpr, 6(5), pp. 561-579. Zhao, X., Zhang, L. and Liu, D., 2012. Biomass recalcitrance. Part I: the chemical compositions and physical structures affecting the enzymatic hydrolysis of lignocellulose. Biofuels Bioproducts & Biorefining-Biofpr, 6(4), pp. 465-482. Liu, D., Zhang, W., Mou, D., He, J., Ou, Y.-B., Wang, Q.-Y., Li, Z., Wang, L., Zhao, L., He, S., Peng, Y., Liu, X., Chen, C., Yu, L., Liu, G., Dong, X., Zhang, J., Chen, C., Xu, Z., Hu, J., Chen, X., Ma, X., Xue, Q. and Zhou, X.J., 2012. Electronic origin of high-temperature superconductivity in single-layer FeSe superconductor. Nature Communications, 3, pp. Zhao, X., Cheng, K. and Liu, D., 2009. Organosolv pretreatment of lignocellulosic biomass for enzymatic hydrolysis. Applied Microbiology and Biotechnology, 82(5), pp. 815-827.