单冰 - 中国科学院上海有机化学研究所 -

个人简介

2013年11月至今副研究员中国科学院上海有机化学研究所生物与化学交叉研究中心 2011年10月至2013年8月博士后美国Scripps研究所 2010年9月至2011年9月博士后德国马普精神病研究所 2007年9月至2010年8月博士慕尼黑大学

研究领域

细胞坏死及神经退行性疾病的质谱蛋白质组学研究

近期论文

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1.Ryan SD, Dolatabadi N, Chan SF, Zhang X, Akhtar MW, Parker J, Soldner F, Sunico CR, Nagar S, Talantova M, Lee B, Lopez K, Nutter A, Shan B, Molokanova E, Zhang Y, Han X, Nakamura T, Masliah E, Yates JR 3rd, Nakanishi N, Andreyev AY, Okamoto S, Jaenisch R, Ambasudhan R, Lipton SA. Isogenic Human iPSC Parkinson's Model Shows Nitrosative Stress-Induced Dysfunction in MEF2-PGC1α Transcription. Cell. 2013 Dec 5;155(6):1351-64. Epub 2013 Nov 27. 2.Zhang Y, Fonslow BR, Shan B, Baek MC, Yates JR 3rd. Protein analysis by shotgun/bottom-up proteomics. Chem Rev. 2013 Apr 10;113(4):2343-94. Epub 2013 Feb 26. 3.Curic S, Wu Y, Shan B, Schaaf C, Utpadel D, Lange M, Kuhlen D, Perone MJ, Arzt E, Stalla GK, Renner U. Curcumin acts anti-proliferative and pro-apoptotic in human meningiomas. J Neurooncol. 2013 Jul;113(3):385-96. doi: 10.1007/s11060-013-1148-9. Epub 2013 May 11 4.Monteserin-Garcia J, Al-Massadi O, Seoane LM, Alvarez CV, Shan B, Stalla J, Paez-Pereda M, Casanueva FF, Stalla GK, Theodoropoulou M. Sirt1 inhibits the transcription factor CREB to regulate pituitary growth hormone synthesis. FASEB J. 2013 Apr;27(4):1561-71. doi: 10.1096/fj.12-220129. Epub 2013 Jan 4. 5.Shan B, Schaaf C, Schmidt A, Lucia K, Buchfelder M, Losa M, Kuhlen D, Kreutzer J, Perone M, Arzt E, Stalla GK, Renner U. Curcumin suppresses HIF-1A synthesis and VEGFA release in pituitary adenomas. J Neurooncol. 2013 Jul;113(3):385-96. doi: 10.1007/s11060-013-1148-9. Epub 2013 May 11. 6.Shan B, Gerez J, Haedo M, Fuertes M, Theodoropoulou M, Buchfelder M, Losa M, Stalla GK, Arzt E, Renner U. RSUME is implicated in HIF-1-induced VEGF-A production in pituitary tumour cells. Endocr Relat Cancer. 2012 Jan 9;19(1):13-27. Print 2012 Feb. 7.Schaaf C, Shan B, Onofri C, Stalla GK, Arzt E, Schilling T, Perone MJ, Renner U. Curcumin inhibits the growth, induces apoptosis and modulates the function of pituitary folliculostellate cells. Neuroendocrinology. 2010; 91(2):200-10. Epub 2010 Feb 17. 8.Schaaf C, Shan B, Buchfelder M, Losa M, Kreutzer J, Rachinger W, Stalla GK, Schilling T, Arzt E, Perone MJ, Renner U. Curcumin acts anti-tumourigenic and hormone-suppressive in murine and human pituitary tumour cells in vitro and in vivo. Endocr Relat Cancer. 2009 Dec; 16(4):1339-50