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开展具有不对称催化合成、药物中间体合成及药物合成工艺优化以及基于天然产物的结构修饰和活性研究等

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synthesis of spiropyrrolidinyl-benzoisothiazoline derivatives by 1,3-dipolar cycloaddtion of benzoisothiazole-2,2-dioxide-3-ylidenes and azomethine ylide Caoguorui, Huang Longjiang, Teng Dawei, Tetrahedron,2014,70 (49),9359-9365 Hui Hong, Longjiang Huang, Dawei Teng, A spirocyclic oxindole analogue: Synthesis and antitumor activities, Chinese Chemical Letters, 2011(9), 1009-1012. Longjiang Huang, Dawei Teng, An improved and scalable process for 3,8-diazabicyclo[3.2.1]octane analogues, Chinese Chemical Letters, 2011(5), 523-526. Longjiang Huang, Dequan Yu; Total synthesis and biological evaluation of (1)- and (2)-Butyl ester of rosmarinic acid Journal of asian natural product research ,2006、8(6)、561-566, Longjiang Huang Total synthesis of natural product (R)-4-phenyl-2-O- [b-Dxylopy ranosyl(1-6)-b-D-glucopyranosyl]butane and its epimer Journal of asian naturalproduct research, 2007、9(3)、223-231

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