冯巍 - 中国科学院大学 - 生命科学学院

个人简介

招生方向定量生物学合成生物学非平衡态统计教育背景 2008-09--2012-11 香港大学博士 2004-09--2008-06 浙江大学学士工作经历 2016-09-至今中科院深圳先进技术研究院合成生物学研究所（筹）研究员 2013-03--2016-09 耶鲁大学分子细胞发育生物学系博士后科研项目（ 1 ）关于细菌生长速率与趋化运动能力间权衡机制的研究, 主持, 国家级, 2016-01--2019-12 （ 2 ）关于细菌逃避中性粒细胞追逐的最优策略研究, 主持, 国家级, 2016-01--2018-12 （ 3 ）耐药性致病细菌快速检测芯片研发, 参与, 省级, 2018-01--2019-12 （ 4 ）青年****配套, 主持, 部委级, 2017-12--2018-12 （ 5 ）人工改造噬菌体治疗超级耐药菌新技术的研发, 参与, 省级, 2015-11--2020-11 （ 6 ）耐药性致病细菌快速检测芯片研究, 参与, 省级, 2017-06--2020-06 （ 7 ）国防类项目, 参与, 国家级, 2017-06--2019-06 （ 8 ）高版本模式微生物底盘细胞, 主持, 国家级, 2019-07--2024-06

近期论文

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1. Xu, Y., Ren, J., He, X., Chen, H., Wei, T.*, and Feng, W.*,(2019). "YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization." Autophagy (DOI: 10.1080/15548627.2019.1569928). (*: corresponding authors) 2. Liang, R., Ren, J., Zhang, Y., and Feng, W.*, (2019). "Structural Conservation of the Two Phosphoinositide-Binding Sites in WIPI Proteins. " J Mol Biol 431 (7): 1494-1505.(*: corresponding authors) 3. Ren, J., Wang, S., Chen, H., Wang, W., Huo, L., and Feng, W.*, (2018). "Coiled-coil 1-mediated fastening of the neck and motor domains for kinesin-3 autoinhibition. " Proc Natl Acad Sci U S A 115(51): E11933-E11942 (*: corresponding authors) 4. Ren, J., Zhang, Y., Wang, S., Huo, L., Lou, J., and Feng, W.*, (2018). "Structural Delineation of the Neck Linker of Kinesin-3 for Processive Movement. " J Mol Biol 430(14):2030-2041. (*: corresponding authors) 5. Yi, F., Kong, R., Ren, J., Zhu, L., Lou, J., Wu, J.Y., and Feng, W.*, (2016) "Noncanonical Myo9b-RhoGAP Accelerates RhoA GTP Hydrolysis by a Dual-Arginine-Finger Mechanism" J Mol Biol. 428(15): 3043-57. (*: corresponding authors) 6. Ren, J., Huo, L., Wang, W., Zhang, Y., Li, W., Lou, J., Xu, T., and Feng, W.*, (2016) "Structural Correlation of the Neck Coil with the Coiled-coil (CC1)-Forkhead-associated (FHA) Tandem for Active Kinesin-3 KIF13A" J Biol Chem. 291(7): 3581-94.(*: corresponding authors) 7. Nie, S., Ke, H., Gao, F., Ren, J., Wang, M., Huo, L., Gong, W., and Feng, W.*, (2016) "Coiled-Coil Domains of SUN Proteins as Intrinsic Dynamic Regulators" Structure. 24(1): 80-91.(*: corresponding authors) 8. Ren, J., Feng, L., Bai, Y., Pei, H., Yuan, Z., and Feng, W.*, (2015) "Interdomain interface-mediated target recognition by the Scribble PDZ34 supramodule" Biochem J. 468(1): 133-44.(*: corresponding authors) 9. Kong, R., Yi, F., Wen, P., Liu, J., Chen, X., Ren, J., Li, X., Shang, Y., Nie, Y., Wu, K., Fan, D., Zhu, L.*, Feng, W.*, and Wu, J.Y.*, (2015) "Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression" J Clin Invest. 125(12): 4407-20.(*: corresponding authors) 10. Zhang, Y., Wang, W., Chen, J., Zhang, K., Gao, F., Gao, B., Zhang, S., Dong, M., Besenbacher, F., Gong, W., Zhang, M., Sun, F.*, and Feng, W.*, (2013) "Structural insights into the intrinsic self-assembly of Par-3 N-terminal domain" Structure. 21(6): 997-1006.(*: corresponding authors) 11. Wang, C., Li, W., Ren, J., Fang, J., Ke, H., Gong, W., Feng, W.*, and Wang, C.C.*, (2013) "Structural insights into the redox-regulated dynamic conformations of human protein disulfide isomerase" Antioxid Redox Signal. 19(1): 36-45.(*: corresponding authors) 12. Huo, L., Yue, Y., Ren, J., Yu, J., Liu, J., Yu, Y., Ye, F., Xu, T.*, Zhang, M.*, and Feng, W.*, (2012) "The CC1-FHA tandem as a central hub for controlling the dimerization and activation of kinesin-3 KIF1A" Structure. 20(9): 1550-61.(*: corresponding authors) 13. Huo, L., Wen, W., Wang, R., Kam, C., Xia, J., Feng, W.*, and Zhang, M.*, (2011) "Cdc42-dependent formation of the ZO-1/MRCKb complex at the leading edge controls cell migration" EMBO J. 30(4): 665-78.(*: corresponding authors) 14. Yu, C.#, Feng, W.#, Wei, Z., Miyanoiri, Y., Wen, W., Zhao, Y., and Zhang, M., (2009) "Myosin VI undergoes cargo-mediated dimerization" Cell. 138(3): 537-48. (#: co-first authors) 15. Feng, W. and Zhang, M., (2009) "Organization and dynamics of PDZ-domain-related supramodules in the postsynaptic density" Nat Rev Neurosci. 10(2): 87-99.(invited review) 16. Wu, H.#, Feng, W.#, Chen, J., Chan, L.N., Huang, S., and Zhang, M., (2007) "PDZ domains of Par-3 as potential phosphoinositide signaling integrators" Mol Cell. 28(5): 886-98. (#: co-first authors)