个人简介
工作经历
2009-至今 中国科学院微生物研究所,研究员
2007-2009 Texas A&M University, 博士后 (研究生物钟信号输出机制)
2006-2007 University of Texas-Southwestern Medical Center, 博士后 (研究蛋白磷酸化在生物钟信号传递中的作用)
2005-2006 Northern Illinois University, 博士后 (研究真菌形态发育)
1997-2000 中国农业科学院生物防治研究所,研实、助研(研发农用抗生素)
教育经历
2001-2005 University of Nebraska-Lincoln,博士,植物病理学
1994-1997 扬州大学,硕士,生物化学
1990-1994 山西农业大学,本科,作物
近期论文
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Xianyun Sun*, Fei Wang, Nan Lan, Bo Liu, Chengcheng Hu, Wei Xue, Zhenying Zhang, Shaojie Li. (2019). The Zn(II)2Cys6-type transcription factor ADA-6 regulates conidiation, sexual development, and oxidative stress response in Neurospora crassa. Front Microbiol, 10: e750
Wei Xue, Yajing Yin, Fatima Ismail, Chengcheng Hu, Mi Zhou, Xianhe Cao, Shaojie Li, Xianyun Sun*. (2019). Transcription factor CCG-8 plays a pivotal role in azole adaptive responses of Neurospora crassa by regulating intracellular azole accumulation. Curr Genet, 65(3): 735-745.
Chengcheng Hu, Mi Zhou, Wenzhao Wang, Xianyun Sun, Oded Yarden, Shaojie Li*. (2018). Abnormal ergosterol biosynthesis activates transcriptional responses to antifungal azoles. Front Microbiol, 9: e9.
Xiaokui Gu, Wei Xue, Yajing Yin, Hongwei Liu, Shaojie Li, Xianyun Sun*. (2016). The Hsp90 co-chaperones Sti1, Aha1, and P23 regulate adaptive responses to antifungal azoles. Front Microbiol, 7: e1571.
Xi Chen, Wei Xue, Jun Zhou, Zhenying Zhang, Shiping Wei, Xingyu Liu, Xianyun Sun, Wenzhao Wang, Shaojie Li*. (2016). De-repression of CSP-1 activates adaptive responses to antifungal azoles. Sci Rep. 6: e19447.
Yunkun Dang#, Jiasen Cheng#, Xianyun Sun, Zhipeng Zhou, Yi Liu*. (2016). Antisense transcription licenses nascent transcripts to mediate transcriptional gene silencing. Genes & Dev. 30: 2417-2432.
Bingzhi Chen, Arend F. van Peer, Junjie Yan, Xiao Li, Bin Xie, Juan Miao, Qianhui Huang, Lei Zhang, Wei Wang, Junsheng Fu, Xiang Zhang, Xiaoyin Zhang, Fengli Hu, Qingfang Kong, Xianyun Sun, Feng Zou, Hanxing Zhang, Shaojie Li*, Baogui Xie*. (2016). Fruiting body formation in Volvariella volvacea can occur independently of its MAT-A-controlled bipolar mating system, enabling homothallic and heterothallic life cycles. G3 (Bethesda). 6(7): 2135-2146.
Kangji Wang, Zhenying Zhang, Xi Chen, Xianyun Sun, Cheng Jin, Hongwei Liu*, Shaojie Li*. (2015). Transcription factor ADS-4 regulates adaptive responses and resistance to antifungal azole stress. Antimicrob Agents Chemother. 59(9): 5396-5404.
Xianyun Sun, Kangji Wang, Xinxu Yu, Jie Liu, Hanxing Zhang, Fucai Zhou, Baogui Xie, Shaojie Li*. (2014). Transcription factor CCG-8 as a new regulator in the adaptation to antifungal azole stress. Antimicrob Agents Chemother, 58(3): 1434-1442.
Nan Lan, Hanxing Zhang, Chengcheng Hu, Wenzhao Wang, Ana M. Calvo, Steven D. Harris, She Chen, Shaojie Li*. (2014). Coordinated and distinct functions of Velvet proteins in Fusarium verticillioides. Eukaryot Cell. 13(7): 909-918.
Saifei Li, Yali Xi, Caixia Qi, Qianqian Liang, Shenglong Wei, Guojie Li, Dong Zhao, Shaojie Li*, Huaan Wen*. (2014). Agaricus taeniatus sp. nov., a new member of Agaricus sect. Biverales from northwest China. Mycotaxon. 129(1): 187-196.
Zhenyu Zhang, Qiuying Yang, Guangyan Sun, She Chen, Qun He, Shaojie Li, Yi Liu*. (2014). Histone H3K56 acetylation is required for quelling-induced small RNA production through its role in homologous recombination. J Biol Chem. 289(13): 9365-9371.
Qiuying Yang, Liande Li, Zhihong Xue, Qiaohong Ye, Lin Zhang, Shaojie Li, Yi Liu*. (2013). Transcription of the major Neurospora crassa microRNA-like small RNAs relies on RNA polymerase III. PLoS Genet. 9(1): e1003227.
Zhenyu Zhang,Shwu-Shin Chang, Zhenying Zhang, Zhihong Xue, Hanxing Zhang, Shaojie Li, Yi Liu*. (2013). Homologous recombination as a mechanism to recognize repetitive DNA sequences in an RNAi pathway. Genes & Dev. 27: 145-150.
Jufen Zhu, Xinxu Yu, Baogui Xie*, Xiaokui Gu, Zhenying Zhang, Shaojie Li*. (2013). Transcriptomic profiling-based mutant screen reveals three new transcription factors mediating menadione resistance in Neurospora crassa. Fungal Biol-UK, 117(6): 422–430.
Xianyun Sun, Wenzhao Wang, Kangji Wang, Xinxu Yu, Jie Liu, Fucai Zhou, Baogui Xie, Shaojie Li*. (2013). Sterol C-22 desaturase ERG5 mediates the sensitivity to antifungal azoles in Neurospora crassa and Fusarium verticillioides. Front Microbiol, 4: 195-200.
Xianyun Sun, Shu Kang, Yongjie Zhang, Xinqiu Tan, Yufei Yu, Haiyong He, Xinyu Zhang, Yongfeng Liu, Shu Wang, Wenxian Sun, Lei Cai, Shaojie Li*. (2013). Genetic diversity and population structure of rice pathogen Ustilaginoidea virens in China. PLoS ONE ,8(9): e76879
Bingzhi Chen, Fu Gui, Baogui Xie*, Youjin Deng, Xianyun Sun, Mengying Lin, Yongxin Tao, Shaojie Li*. (2013). Composition and expression of genes encoding carbohydrate-active enzymes in the straw-degrading mushroom Volvariella volvacea,PLoS ONE, 8(3): e58780
Xianyun Sun, Jufen Zhu, Li Bao, Chengcheng Hu, Cheng Jin, Steven D. Harris, Hongwei Liu, Shaojie Li*. (2013). PyrG is required for maintaining stable cellular uracil level and normal sporulation pattern under excess uracil stress in Aspergillus nidulans. Sci China Life Sci, 56(5): 467–475.