郭惠珊 - 中国科学院微生物研究所 -

个人简介

学习经历 1983.9-1987.7 中山大学生物学，学士 1993.6-1996.6 西班牙马德里大学，博士工作经历 1987.9-1991.12 中山大学生物工程中心，助教 1992.1-1993.5 西班牙马德里大学"Severo Ochoa"分子生物学中心，Guest Investigator 1997.7-1998.6 西班牙马德里大学国家生物工程中心（CSIC）博士后 1998.7-2003.1 新加坡国立大学分子农业生物学院/淡马锡生命科学研究院Research Fellow 2003.1-2004.6 新加坡国立大学淡马锡生命科学研究院，Acting PI 2004.7-至今中国科学院微生物所研究员、博士生导师

研究领域

1、植物RNA沉默的分子机制及其抗病应用研究； 2、植物与真菌的互作机理及维管束真菌病害的防控策略研究

近期论文

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Qin, J., Wang, K., Sun, L., Xing, H., Wang, S., Li, L., Chen, S., Guo, H.S.*, and Zhang, J.* (2018). The plant specific transcription factors CBP60g and SARD1 are targeted by a Verticillium secretory protein VdSCP41 to modulate immunity. eLife 7. Jin, Y.#, Zhao, P.#, Fang, Y.-Y., Gao, F., Guo, H.S.*, and Zhao, J.H.* (2018). Genome-wide profiling of sRNAs in the Verticillium dahliae-infected Arabidopsis roots. Mycology, 1-11. Hua,C.L., Zhao, J.H., and Guo, H.S.* (2018). Trans-kingdom RNA silencing in Plant–Fungal Pathogen Interactions. Mol Plant 11, 235-244. Du, X., Wang, S., Gao, F., Zhang, L., Zhao, J.H., Guo, H.S.*, and Hua, C*. (2017). Expression of pathogenesis-related genes in cotton roots in response to Verticillium dahliae PAMP molecules. Science China. Life sciences 60, 852-860. Jin, Y., Zhang, T., and Guo, H.S.* (2017). Application of host induced gene silencing in crop protection against fungal diseases. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 33, 161-169. Zhang, L., Ni, H., Du, X., Wang, S., Ma, X.W., Nurnberger, T., Guo, H.S.*, and Hua, C*. (2017). The Verticillium-specific protein VdSCP7 localizes to the plant nucleus and modulates immunity to fungal infections. The New phytologist 215, 368-381. Zhao, Y.L.*, Zhang, T., and Guo, H.S. (2017). Penetration Assays, Fungal Recovery and Pathogenicity Assays for Verticillium dahliae. Bio-Protocol 7. Zhou, T.T., Zhao, Y.L., and Guo, H.S.* (2017). Secretory proteins are delivered to the septin-organized penetration interface during root infection by Verticillium dahliae. PLoS pathogens 13, e1006275. Fang, Y.-Y., Zhao, J.-H., Liu, S.-W., Wang, S., Duan, C.-G., and Guo, H.-S.* (2016). CMV2b-AGO Interaction Is Required for the Suppression of RDR-Dependent Antiviral Silencing in Arabidopsis. Frontiers in Microbiology 7, 1329. Lv, D.Q., Liu, S.W., Zhao, J.H., Zhou, B.J., Wang, S.P., Guo, H.S., and Fang, Y.Y. * (2016). Replication of a pathogenic non-coding RNA increases DNA methylation in plants associated with a bromodomain-containing viroid-binding protein. Scientific reports 6, 35751. Wang, S., Xing, H., Hua, C., Guo, H.S.*, and Zhang, J.* (2016). An improved single-step cloning strategy simplifies the Agrobacterium tumefaciens-mediated transformation (ATMT)-based gene disruption method in Verticillium dahliae. Phytopathology. Zhang, T., Jin, Y., Zhao, J.H., Gao, F., Zhou, B.J., Fang, Y.Y., and Guo, H.S.* (2016). Host-Induced Gene Silencing of the Target Gene in Fungal Cells Confers Effective Resistance to the Cotton Wilt Disease Pathogen Verticillium dahliae. Mol Plant 9, 939-942. Zhang, T., Zhao, Y.L., Zhao, J.H., Wang, S., Jin, Y., Chen, Z.Q., Fang, Y.Y., Hua, C.L., Ding, S.W., and Guo, H.S.* (2016). Cotton plants export microRNAs to inhibit virulence gene expression in a fungal pathogen. Nature plants 2, 16153. Zhao, J.H.*, Fang, Y.Y., Duan, C.G., Fang, R.X., Ding, S.W., and Guo, H.S.* (2016). Genome-wide identification of endogenous RNA-directed DNA methylation loci associated with abundant 21-nucleotide siRNAs in Arabidopsis. Scientific reports 6, 36247. Zhao, J.H., Hua, C.L., Fang, Y.Y., and Guo, H.S.* (2016). The dual edge of RNA silencing suppressors in the virus-host interactions. Current opinion in virology 17, 39-44. Zhao, Y.L., Zhou, T.T., and Guo, H.S.* (2016). Hyphopodium-Specific VdNoxB/VdPls1-Dependent ROS-Ca2+ Signaling Is Required for Plant Infection by Verticillium dahliae. PLoS pathogens 12, e1005793. Fang, Y.Y., Smith, N.A., Zhao, J.H., Lee, J.R., Guo, H.S., and Wang, M.B.* (2015). Cloning and profiling of small RNAs from cucumber mosaic virus satellite RNA. Methods in molecular biology 1236, 99-109. Jin, Y., and Guo, H.S.* (2015). Transgene-induced gene silencing in plants. Methods Mol Biol 105-117. Shen, W.X., Au, P.C., Shi, B.J., Smith, N.A., Dennis, E.S., Guo, H.S., Zhou, C.Y., and Wang, M.B.* (2015). Satellite RNAs interfere with the function of viral RNA silencing suppressors. Front Plant Sci 281. Wang, J.J., Zhang, L., and Guo, H.S.* (2015). Arabidopsis Leaf Explant Culture. Bio-Protocol 5(22).