李晓雯 - 青岛大学 - 化学化工学院

研究领域

主要从事生物无机化学和药物化学等方面的相关教学与科研工作。研究内容主要包括：1. 基于生物大分子相互作用的抗肿瘤药物的设计与合成研究；2. 药物中间体的合成研究；3. 海洋活性产物的结构修饰与优化。

近期论文

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Xiao-Wen Li, Yong-Jun Zheng, Yan-Tuan Li*, Zhi-Yong Wu, Cui-Wei Yan. Synthesis and structure of new bicopper(II) complexes bridged by N-(2-aminopropyl)-N’- (2-oxidophenyl)oxamide: The effects of terminal ligands on structures, anticancer activities and DNA-binding properties. Eur. J. Med. Chem., 46, 3851–3857, 2011 Xiao-Wen Li, Lin Tao, Yan-Tuan Li*, Zhi-Yong Wu, Cui-Wei Yan. Bimetallic complexes constructed from asymmetrical N,N’-bis(substituted)oxamide: Cytotoxicities, and reactivities towards DNA and protein. Eur. J. Med. Chem., 54, 697–708, 2012 Xiao-Wen Li, Xue-Jie Li, Yan-Tuan Li*, Zhi-Yong Wu, Cui-Wei Yan. Syntheses and structures of new trimetallic complexes bridged by N-(5-chloro-2-hydroxyphenyl)-N’-[3-(dimethylamino)propyl]oxamide: Cytotoxic activities, and reactivities towards DNA and protein. J. Photoch. Photobio. B, 118, 22-32, 2013 Xiao-Wen Li, Yu Yu, Yan-Tuan Li*, Zhi-Yong Wu, Cui-Wei Yan. Synthesis, structure, cytotoxic activities and DNA-binding properties of tetracopper(II) complexes with dissymmetrical N,N’-bis(substituted)oxamides as ligands. Inorg. Chim. Acta, 367, 64–72, 2011 Xiao-Wen Li, Xin Li, Yan-Tuan Li*, Zhi-Yong Wu, Cui-Wei Yan. Synthesis and structures of binuclear copper(II) complexes bridged by N-(5-chloro-2-hydroxyphenyl)-N’-[3-(dimethylamino)propyl]oxalamide ligand: DNA-binding properties and cytotoxic activities. J. Organ. Chem., 700, 48–57, 2012 Xiao-Wen Li, Yan-Tuan Li*, Zhi-Yong Wu, Cui-Wei Yan. Syntheses and structures of bicopper(II) complexes bridged by N-(5-chloro-2-hydroxyphenyl)-N’-[3- (dimethylamino)propyl]oxamide: cytotoxic activities, and reactivities towards DNA and protein. Inorg. Chim. Acta, 390, 190-198, 2012