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个人简介

2017.07-至今 南京林业大学化学工程学院 教授 2010.09-2017.08 南京林业大学化学工程学院 副教授 2007.07-2010.08 南京林业大学化学工程学院 讲师

研究领域

1.林源天然萜类物质的合成改性及其综合利用 2.新型抗真菌农药的设计、合成和应用 3.新型功能荧光分子的设计、合成和应用

近期论文

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Xue-Bao Sun, Zi-Hui Yang, Dao-Jun Jin, Yi-Gui Qiu, Wen Gu*, Design, synthesis and antifungal evaluation of novel nopol derivatives as potent laccase inhibitors, Pest Management Science 2023, DOI10.1002/ps.7426. Lu Sun, Zhong-Long Wang, Lin-Lin Chen, Xue-Bao Sun, Zi-Hui Yang, Wen Gu*,A novel dehydroabietic acid-based multifunctional fluorescent probe for the detection and bioimaging of Cu2+/Zn2+/ClO−, Analyst 2023, DOI10.1039/d3an00001j. Zi-Hui Yang, Xue-Bao Sun, Dao-Jun Jin, Yi-Gui Qiu, Lin-Lin Chen, Lu Sun, Wen Gu*, Novel Camphor Sulfonohydrazide and Sulfonamide Derivatives as Potential Succinate Dehydrogenase Inhibitors against Phytopathogenic Fungi/Oomycetes, Journal of Agricultural and Food Chemistry 2023, 71, 174-185. Lu Sun, Ming-Xin Li, Lin-Lin Chen, Xue-Bao Sun, Zi-Hui Yang, Shi-Fa Wang, Wen Gu*, A highly sensitive dehydroabietic acid-based difunctional fluorescent probe for detecting formaldehyde and Ag+, Journal of Luminescence 2023, 257, 119658. Lin-Lin Chen, Zhong-Long Wang, Lu Sun, Xue-Bao Sun, Wen Gu*, A highly effective turn-on tanshinone IIA-based fluorescent probe for rapid and sensitive detection of ClO- and its application in environmental analysis and bioimaging. Journal of Photochemistry & Photobiology, A: Chemistry 2023, 438, 114533. Yue Sun, Zi-Hui Yang, Qing-Song Liu, Xue-Bao Sun, Lin-Lin Chen, Lu Sun, Wen Gu*, Design, synthesis, and fungicidal evaluation of novel 1,3-benzodioxole-pyrimidine derivatives as potential succinate dehydrogenase inhibitors, Journal of Agricultural and Food Chemistry 2022, 70, 7360-7374. Zi-Hui Yang, Xue-Bao Sun, Dao-Jun Jin, Yi-Gui Qiu, Shi-Fa Wang, Wen Gu*, Synthesis and antifungal/anti- oomycete activity of novel camphor-based sulfonate derivatives as potential SDH inhibitors, Journal of Molecular Structure 2022, 1270, 133959. Zi-Hui Yang, Xue-Bao Sun, Dao-Jun Jin, Yi-Gui Qiu, Lin-Lin Chen, Lu Sun, Wen Gu*, Synthesis and anti-fungal/oomycete activity of novel sulfonamide derivatives containing camphor scaffold. Chemistry & Biodiversity 2022, 19, e202200608. Qing-Song Liu, Lin-Lin Chen, Zhong-Long Wang, Zi-Hui Yang, Yue Sun, Shi-Fa Wang, Wen Gu*, A highly sensitive “turn-on ”dehydroabietic acid-based fluorescent probe for rapid sensing HSO3− and its application in sugar samples, living cells, and zebrafish, Chinese Journal of Analytical Chemistry 2022, 50.8, 100122. Zi-Hui Yang, Qing-Song Liu, Yue Sun, Xue-Bao Sun, Lu Sun, Lin-Lin Chen, Wen Gu*, Novel aromatic carboxamides from dehydroabietylamine as potential fungicides: Design, synthesis and antifungal evaluation. Arabian Journal of Chemistry 2022, 15, 104330. Wen-Yan Wang, Zi-Hui Yang, A-Liang Li, Qing-Song Liu, Yue Sun, Wen Gu*, Design, synthesis, anticancer activity and mechanism studies of novel 2-amino-4-aryl-pyrimidine derivatives of ursolic acid, New Journal of Chemistry 2022, 46, 2335–2350. Qing-Song Liu, Zi-Hui Yang, Zhong-Long Wang, Yue Sun, Lin-Lin Chen, Lu Sun, Xue-Bao Sun, Wen Gu*, A novel dehydroabietic acid-based AIE-active fluorescent probe for rapid detection of Hg2+ and its environmental and biological applications, Journal of Photochemistry & Photobiology, A: Chemistry 2022, 423, 113597. Zi-Hui Yang, Yue Sun, Qing-Song Liu, A-Liang Li, Wen-Yan Wang, Wen Gu*, Design, synthesis, and antifungal activity of novel thiophene/furan-1,3,4-oxadiazole carboxamides as potent succinate dehydrogenase inhibitors, Journal of Agricultural and Food Chemistry 2021, 69, 13373-13385. A-Liang Li, Zhong-Long Wang, Wen-Yan Wang, Qing-Song Liu, Yue Sun, Wen Gu*, A novel dehydroabietic acid-based turn-on fluorescent probe for the detection of bisulfite and its application in live-cell and zebrafish imaging, New Journal of Chemistry 2021, 45, 16822-16832. Wen-Yan Wang, Wen-Yi Wu, A-Liang Li, Qing-Song Liu, Yue Sun, Wen Gu*, Synthesis, anticancer evaluation and mechanism studies of novel indolequinone derivatives of ursolic acid, Bioorganic Chemistry 2021, 109, 104705. Zi-Hui Yang, Qing-Song Liu, Yue Sun, Xue-Bao Sun, Lin-Lin Chen, Lu Sun, Wen Gu*, Synthesis, antifungal activity, dft study and molecular dynamics simulation of novel 4-(1,2,4-oxadiazol-3-yl)-N-(4-phenoxyphenyl) benzamide derivatives, Chemistry & Biodiversity 2021, 18, e202100651. A-Liang Li, Zhong-Long Wang, Wen-Yan Wang, Qing-Song Liu, Yue Sun, Shi-Fa Wang, Wen Gu*, A novel dehydroabietic acid-based fluorescent probe for detection of Fe3+ and Hg2+ ions and its application in live-cell imaging, Microchemical Journal 2021, 160, 105682. Ya-Qun Yang, Hao Chen, Qing-Song Liu, Yue Sun, Wen Gu*, Synthesis and anticancer evaluation of novel 1H-benzo[d]imidazole derivatives of dehydroabietic acid as PI3Kα inhibitors, Bioorganic Chemistry 2020, 100, 103845. A-Liang Li, Yun Hao, Wen-Yan Wang, Qing-Song Liu, Yue Sun, Wen Gu*, Design, synthesis, and anticancer evaluation of novel indole derivatives of ursolic acid as potential Topoisomerase II inhibitors, International Journal of Molecular Sciences 2020, 21, 2876. Hao Chen, Chao Qiao, Ting-Ting Miao, A-Liang Li, Wen-Yan Wang, Wen Gu*, Synthesis and biological evaluation of novel N-(piperazin-1-yl)alkyl-1H-dibenzo[a,c]carbazole derivatives of dehydroabietic acid as potential MEK inhibitors, Journal of Enzyme Inhibition and Medicinal Chemistry 2019, 34, 1544-1561. Xiao-Yan Jin, Hao Chen, Dong-Dong Li, A-Liang Li, Wen-Yan Wang, Wen Gu*, Design, synthesis, and anticancer evaluation of novel quinoline derivatives of ursolic acid with hydrazide, oxadiazole, and thiadiazole moieties as potent MEK inhibitors, Journal of Enzyme Inhibition and Medicinal Chemistry 2019, 34, 955-972. Ting-Ting Miao, Xu-Bing Tao, Dong-Dong Li, Hao Chen, Xiao-Yan Jin, Yi Geng, Shi-Fa Wang, Wen Gu*, Synthesis and biological evaluation of 2-aryl- benzimidazole derivatives of dehydroabietic acid as novel tubulin polymerization inhibitors, RSC Advances 2018, 8, 17511-17526. Xiao-Yan Jin, Kang-Ping Zhang, Hao Chen, Ting-Ting Miao, Shi-Fa Wang, Wen Gu*, Synthesis, in vitro antimicrobial, and cytotoxic activities of new 1,3,4-oxadiazin-5(6H)-one derivatives from dehydroabietic acid, Journal of the Chinese Chemical Society 2018, 65, 538-547.

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