个人简介
Klaus Schulten received his Ph.D. from Harvard University in 1974. He is Swanlund Professor of Physics and is affliliated with the Department of Chemistry, the Center for Biophysics and Computational Biology and the Biotechnology Center. Prof. Schulten is a full time faculty member of the Beckman Institute and directs the Theoretical and Computational Biophysics Group. His professional interest are theoretical physics and theoretical biology.
研究领域
His professional interest are theoretical physics and theoretical biology. His current research focuses on the structure and function of supramolecular systems in the living cell, and on the development of efficient computing tools for structural biology.
近期论文
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"Three dimensional architecture of membrane-embedded MscS in the closed conformation." Valeria Vasquez, Marcos Sotomayor, D. Marien Cortes, Benoit Roux, Klaus Schulten, and Eduardo Perozo. Journal of Molecular Biology, 2007. In press.
"Double stranded DNA dissociates into single strands when dragged into a poor solvent." Shuxun Cui, Jin Yu, Ferdinand Kühner, Klaus Schulten, and Hermann E. Gaub. Journal of the American Chemical Society, 2007. In press.
"Biomolecular modeling in the era of petascale computing". Klaus Schulten, James C. Phillips, Laxmikant V. Kalé, and Abhinav Bhatele. In David Bader, editor, Petascale Computing: Algorithms and Applications, pp. 165-181. Chapman and Hall/CRC Press, Taylor and Francis Group, New York, 2008. In press.
"Mapping the two-dimensional reaction landscape of Holliday junction via dynamic fluorescence-force spectroscopy." Sungchul Hohng, Ruobo Zhou, Michelle K. Nahas, Jin Yu, Klaus Schulten, David M. J. Lilley, and Taekjip Ha. Science, 318:279-283, 2007.
"Atomic level structural and functional model of a bacterial photosynthetic membrane vesicle." Melih K. Sener, John D. Olsen, C. Neil Hunter, and Klaus Schulten. Proceedings of the National Academy of Sciences, USA, 104:15723-15728, 2007.
"Accelerating molecular modeling applications with graphics processors." John E. Stone, James C. Phillips, Peter L. Freddolino, David J. Hardy, Leonardo G. Trabuco, and Klaus Schulten. Journal of Computational Chemistry, 28:2618-2640, 2007.
"Continuous fluorescence microphotolysis and correlation spectroscopy using 4Pi microscopy." Anton Arkhipov, Jana Hüve, Martin Kahms, Reiner Peters, and Klaus Schulten. Biophysical Journal, 93:4006-4017, 2007.
"Structural determinants of lateral gate opening in the protein translocon." James Gumbart and Klaus Schulten. Biochemistry, 46:11147-11157, 2007.
"O2 migration pathways are not conserved across proteins of a similar fold." Jordi Cohen and Klaus Schulten. Biophysical Journal, 93:3591-3600, 2007.
"Assembly of lipids and proteins into lipoprotein particles." Amy Y. Shih, Anton Arkhipov, Peter L. Freddolino, Stephen G. Sligar, and Klaus Schulten. Journal of Physical Chemistry B, 111:11095-11104, 2007.