个人简介

MPD | Product Development | Rochester Inst Technology 2001 PhD | Physical Chemistry | Penn State University 1984 BS | Chemistry | Providence College 1979

研究领域

Manipulation of materials at the molecular/nano/and micro scales to develop novel biomedical devices for therapeutic and diagnostic applications

The overall research area in the laboratory is the creation of Smart Bandage Biomaterial Engineering and Skin Disease. This laboratory investigates the fundamental optical, morphological, and surface chemical properties of bioengineered nanoporous silicon (PSi) in developing a platform of Smart Bandage technologies targeting biosensors for point of care diagnosis of cutaneous disease, transdermal drug delivery, and tissue engineering for wound healing. PSi is fabricated from single crystal silicon wafers using an electrochemical etch process. The pore diameter, porosity (surface area and internal void volume), bioerosion, and interferometric optical properties can be tailored over a wide range to suit the application.

近期论文

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2014 Sep 21 Bobo B, Phelan D, Rebhahn J, Piepenbrink MS, Zheng B, Mosmann TR, Kobie JJ, DeLouise LA. "Microbubble array diffusion assay for the detection of cell secreted factors." Lab on a chip. 2014 Sep 21; 14(18):3640-50. Epub 2014 Jul 31. 2014 Feb Giang UB, Jones MC, Kaule MJ, Virgile CR, Pu Q, Delouise LA. "Quantitative analysis of spherical microbubble cavity array formation in thermally cured polydimethylsiloxane for use in cell sorting applications." Biomedical microdevices. 2014 Feb; 16(1):55-67. Jatana S, DeLouise LA. "Understanding engineered nanomaterial skin interactions and the modulatory effects of ultraviolet radiation skin exposure." Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology. 2014 6(1):61-79. Epub 2013 Oct 03. 2013 Nov Mortensen LJ, Ravichandran S, Delouise LA. "The impact of UVB exposure and differentiation state of primary keratinocytes on their interaction with quantum dots." Nanotoxicology. 2013 Nov; 7(7):1244-54. Epub 2012 Oct 25. 2013 Jun Jones MC, Kobie JJ, Delouise LA. "Characterization of cell seeding and specific capture of B cells in microbubble well arrays." Biomedical microdevices. 2013 Jun; 15(3):453-63.