个人简介

杜宇慧教授近十年来一直从事人工智能、医学图像处理、大数据分析领域的科研工作，在计算机、信息、医学等学科交叉前沿的脑影像分析领域取得很好的成就，在国内国际上有良好的学术声誉。 她2013年1月在中国科学院自动化研究所获博士学位（模式识别与智能系统专业），2013年5月至2018年8月在美国TheMindResearchNetwork脑影像研究所的VinceDCalhoun教授组里工作，先后任职博士后和PI（PrincipalInvestigator）研究员。至今，杜宇慧教授在《NeuroImage》、《HumanBrainMapping》、《NatureCommunications》等著名杂志发表论文约60篇，其中SCI收录英文文章33篇，SCI论文的影响因子总和约为176。以第一作者或通讯作者发表25篇，其中一区或top期刊文章5篇，二区以上文章10篇。杜宇慧教授以第一作者在2016年发表的一篇论文为ESI“高被引论文”（引用率位于前1%），且入选研究前沿（ResearchFront)论文。目前，谷歌学术显示：杜宇慧教授的论文总引用率为1039，h指数为17，i10指数为28。杜宇慧教授主持和参与多项国家自然科学基金项目，曾参与美国国家国立卫生研究院项目、美国国家科学基金项目、美国生物医学研究卓越项目等项目。杜宇慧教授开发的“组信息指导独立成分分析”（GIG-ICA）脑影像分析方法已被集成到国际上广泛使用的脑影像分析软件GroupICAToolbox（GIFT）中（http://mialab.mrn.org/software/#gica），为该软件组独立成分分析的三大算法之一，而且该方法获得专利和软件著作权。杜宇慧教授两次获得脑影像领域最顶级组织--国际人类脑图谱/脑成像学会（OHBM）颁发的“TraineeAbstractTravelAwards”这一重要奖项。杜宇慧教授是约30种国际著名杂志和会议的特邀审稿人，作为审稿人审理的刊物包括NatureCommunications（SCI影像因子约为12）、TheAmericanJournalofPsychiatry（SCI影响因子约为14）、SchizophreniaBulletin（SCI影响因子约为8）、Neuroimage（神经成像期刊类排名第一）、HumanBrainMapping、IEEETransactionsonNeuralNetworksandLearningSystem、IEEETransactionsonBiomedicalEngineering等。杜宇慧教授是Frontiers杂志的SpecialIssue“IdentifyingNeuroimaging-BasedMarkersforDistinguishingBrainDisorders”的组织者和编辑。杜宇慧在TheMindResearchNetwork研究所工作期间带领NeuroMark团队下的博士后和博士生从事科研工作。杜宇慧与TheMindResearchNetwork、耶鲁大学、德州大学西南医学中心、哈佛大学、中国科学院等国际知名单位合作，进行精神疾病的医学影像标志探索研究。

研究领域

研究方向：脑影像分析、数据挖掘、模式识别、医学图像处理

目前主持国家自然科学基金“基于动态脑功能网络分析发掘精神病的影像标志”，曾参与国家自然科学基金面上项目“基于脑影像的精神分裂症定性诊断与定量分析的模式识别研究”、国家自然科学基金重大研究计划“基于神经影像的脑网络分析方法及其在神经退行性脑疾病研究中的应用”、美国国家国立卫生研究院项目（NIH，NationalInstitutesofHealthgrantsR01EB006841）、美国国家科学基金项目（NationalSciencesFoundationgrants1016619）、美国生物医学研究卓越项目（theCentersofBiomedicalResearchExcellence(COBRE)grant5P20RR021938/P20GM103472）等。

近期论文

查看导师新发文章 （温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

[1]YuhuiDu*,GodfreyDPearlson,JingyuLiu,JingSui,QingbaoYu,HaoHe,EduardoCastro,VinceDCalhoun.AgroupICAbasedframeworkforevaluatingrestingfMRImarkerswhendiseasecategoriesareunclear:applicationtoschizophrenia,bipolar,andschizoaffectivedisorders.NeuroImage,2015,122,272-280. [2]YuhuiDuandYongFan.GroupinformationguidedICAforfMRIdataanalysis.NeuroImage,2013,69:157-197. [3]YuhuiDu*,SusannaLFryer,ZeningFu,DongdongLin,JingSui,JiayuChen,EswarDamaraju,EvaMennigen,BarbaraStuart,RachelL.Loewy,DanielH.Mathalon&VinceD.Calhoun.Dynamicfunctionalconnectivityimpairmentsinearlyschizophreniaandclinicalhigh-riskforpsychosis.Neuroimage,2018,632-645. [4]YuhuiDu*,ElenaAAllen,HaoHe,JingSui,LeiWu,VinceDCalhoun.ArtifactremovalinthecontextofgroupICA:acomparisonofsingle-subjectandgroupapproaches.HumanBrainMapping,2016,37(3):1005-1025. [5]YuhuiDu*,GodfreyD.Pearlson,QingbaoYu,HaoHe,DongdongLin,JingSui,LeiWu,VinceD.Calhoun.Interactionamongsubsystemswithindefaultmodenetworkdiminishedinschizophreniapatients:Adynamicconnectivityapproach.SchizophreniaResearch,2016,170(1):55-65. [6]YuhuiDu*,GodfreyDPearlson,DongdongLin,JingSui,JiayuChen,MustafaSalman,CarolA.Tamminga,ElenaI.Ivleva,JohnA.Sweeney,MatcheriS.Keshavan,BrettA.Clementz,JuanBustillo,VinceD.Calhoun.IdentifyingdynamicfunctionalconnectivitybiomarkersusingGIG-ICA:applicationtoschizophrenia,schizoaffectivedisorderandpsychoticbipolardisorder.HumanBrainMapping,2017,38(5),2683-2708. [7]YuhuiDu*,DongdongLin,JingSui,JiayuChen,QingbaoYu,TulayAdali,VinceD.Calhoun.ComparisonofIVAandGIG-ICAinbrainfunctionalnetworkestimationusingfMRIdata.FrontiersinNeuroscience,2017,11,267. [8]YuhuiDu*,SusannaLFryer,DongdongLin,JingSui,QingbaoYu,JiayuChen,BarbaraStuart,RachelL.Loewy,VinceDCalhoun,DanielHMathalon.Identifyingfunctionalnetworkchangingpatternsinindividualsatclinicalhigh-riskforpsychosisandpatientswithearlyillnessschizophrenia:AgroupICAstudy.Neuroimage:Clinical,2018,17:335-346. [9]YuhuiDu*,ZeningFu,VinceDCalhoun.ClassificationandPredictionofBrainDisordersusingFunctionalConnectivity:PromisingbutChallenging.FrontiersinNeuroscience,2018,12,525. [10]MustafaSSalman,YuhuiDu*,DongdongLin,ZeningFu,AlexFedorova,EswarDamaraju,JingSui,JiayuChen,AndrewMayer,StefanPosse,DanielMathalon,JudithM.Ford,TheodorusVanErp,VinceD.Calhoun..GroupICAforIdentifyingBiomarkersinSchizophrenia:‘Adaptive’NetworksviaSpatiallyConstrainedICAShowMoreSensitivitytoGroupDifferencesthanSpatio-temporalRegression.NeuroImageClinical,2019.https://doi.org/10.1016/j.nicl.2019.101747 [11]YuhuiDu*,GodfreyDPearlson,HaoHe,LeiWu,JiayuChen,VinceDCalhoun.IdentifyingbraindynamicnetworkstatesviaGIG-ICA:Applicationtoschizophrenia,bipolarandschizoaffectivedisorders.IEEE12thInternationalSymposiumonBiomedicalImaging(ISBI),2015,478-481. [12]YuhuiDu*,HaoHe,LeiWu,QingbaoYu,JingSui,VinceDCalhoun.Dynamicdefaultmodenetworkconnectivitydiminishedinpatientswithschizophrenia.IEEE12thInternationalSymposiumonBiomedicalImaging(ISBI),2015,474-477. [13]YuhuiDu*,JingSui,QingbaoYu,HaoHe,GodfreyPearlson,VinceD.Calhoun.Exploringdifferenceandoverlapforschizophrenia,bipolarillnessandschizoaffectivedisorderusingresting-statebrainfunctionalnetworks.The36thAnnualInternationalConferenceoftheIEEEEngineeringinMedicineandBiologySociety(EMBS),2014,1517-1520. [14]YuhuiDu*,ElenaAAllen,HaoHe,JingSui,VinceDCalhoun.BrainfunctionalnetworksextractionbasedonfMRIartifactremoval:Singlesubjectandgroupapproaches.The36thAnnualInternationalConferenceoftheIEEEEngineeringinMedicineandBiologySociety(EMBS),2014,1026-1029. [15]YuhuiDu*,JingSui,QingbaoYu,HaoHe,VinceD.Calhoun.Semi-supervisedlearningofbrainfunctionalnetworks.IEEEInternationalSymposiumonBiomedicalImaging(ISBI),2014,1-4. [16]YuhuiDu*,HongmingLi,andYongFan.IdentificationofsubjectspecificandfunctionalconsistentROIsusingsemi-supervisedlearning.SPIEMedicalImaging,2012,83144S-83144S-7. [17]YuhuiDu*,Zhiguogui,YingjunLiu,FangfangChen.Reviewofindependentcomponentanalysismethodsforbrainfunctionalnetworks,BiophysicsReports,2013,29(4):266-275. [18]YuhuiDu*,ZeningFu,DongdongLin,MustafaSalman,MdAbdurRahaman,AneesAbrol,VinceD.Calhoun.Sharedandspecificchangesinfunctionalnetworksinschizophreniaandautismspectrumdisorder.The24thAnnualMeetingoftheOrganizationforHumanBrainMapping,2018. [19]YuhuiDu*,SusannaLFryer,EvaMennigen,EswarDamaraju,DanielH.Mathalon&VinceD.Calhoun.Clinicalhigh-risksubjectsshowslightimpairmentinbrainnetworkscomparedtoearlyschizophrenia.The22thAnnualMeetingoftheOrganizationforHumanBrainMapping,2016.“TraineeAbstractTravelAwards”. [20]YuhuiDuandYongFan.GroupinformationguidedICAforanalysisofmulti-subjectfMRIdata.The18thAnnualMeetingoftheOrganizationforHumanBrainMapping,2011.“TraineeAbstractTravelAwards”. [21]YuhuiDu*,LirongYan,DannyJJWang,andYongFan.Resting-statebrainnetworksinBOLDfMRIandperfusionfMRI.The19thAnnualMeetingoftheOrganizationforHumanBrainMapping,2012. [22]ZeningFu,YihengTu,XinDi,YuhuiDu,JingSui,BharatBBiswal,ZhiguoZhang,NinadeLacy,VincentDCalhoun.Transientincreasedthalamic-sensoryconnectivityanddecreasedwhole-braindynamisminautism.NeuroImage,2019.191-204. [23]ZeningFu,ArvindCaprihan,JiayuChen,YuhuiDu,JohnCAdair,JingSui,GaryARosenberg,VinceDCalhoun.AlteredstaticanddynamicfunctionalnetworkconnectivityinAlzheimer'sdiseaseandsubcorticalischemicvasculardisease:sharedandspecificbrainconnectivityabnormalities.HumanBrainMapping,2019. [24]ZeningFu,YihengTu,XinDi,YuhuiDu,G.D.Pearlson,J.A.Turner,BharatBBiswal,ZhiguoZhang,V.D.Calhoun,CharacterizingDynamicAmplitudeofLow-FrequencyFluctuationandItsRelationshipwithDynamicFunctionalConnectivity:AnApplicationtoSchizophrenia.NeuroImage,2017. [25]ZeningFu,YihengTu,XinDi,YuhuiDu,JingSui,BharatBBiswal,ZhiguoZhang,NdeLacy,VDCalhoun.Transientincreasedthalamic-sensoryconnectivityanddecreasedwhole-braindynamisminautism.NeuroImage,2018. [26]ZeningFu,YuhuiDu,VinceDCalhoun.TheDynamicFunctionalNetworkConnectivityAnalysisFramework.Engineering.2018. [27]DiJiang,YuhuiDu,HeweiCheng,TianziJiang,andYongFan,GroupwisespatialnormalizationoffMRIdatabasedonmulti-rangefunctionalconnectivitypatterns.NeuroImage,2013,82:355-372. [28]JingSui,GodfreyDPearlson,YuhuiDu,QingbaoYu,ThomasRJones,JiayuChen,TianziJiang,JuanBustillo,VinceDCalhoun.InSearchofMultimodalNeuroimagingBiomarkersofCognitiveDeficitsinSchizophrenia.BiologicalPsychiatry,2015,78(11),794-804. [29]QingbaoYu,ErikBErhardt,JingSui,YuhuiDu,HaoHe,DevonHjelm,MustafaSCetin,SrinivasRachakonda,RobynLMiller,GodfreyPearlson,VinceDCalhoun.Assessingdynamicbraingraphsoftime-varyingconnectivityinfMRIdata:Applicationtohealthycontrolsandpatientswithschizophrenia,NeuroImage,2015,107:345-355. [30]JiayuChen,VinceDCalhoun,NIPerrone-Bizzozero,GodfreyDPearlson,JingSui,YuhuiDu,andJingyuLiu.Apilotstudyoncommonalityandspecificityofcopynumbervariantsinschizophreniaandbipolardisorder.TranslationalPsychiatry-Nature,2016,6,e824;doi:10.1038/tp.2016.96. [31]DongdongLin,JiayuChen,NoraPerrone-Bizzozero,JuanRBustillo,YuhuiDu,VinceDCalhoun,JingyuLiu.Characterizationofcross-tissuegenetic-epigeneticeffectsandtheirpatternsinschizophrenia.Genomemedicine,2018,10:13 [32]QingbaoYu,YuhuiDu,JiayuChen,JingSui,TülayAdalē,GodfreyDPearlson,VinceDCalhoun.ApplicationofGraphTheorytoAssessStaticandDynamicBrainConnectivity:ApproachesforBuildingBrainGraphs.ProceedingsoftheIEEE.2018,106(5),886-906. [33]HaoHe,QingbaoYu,YuhuiDu,VictorVergara,TeresaAVictor,WayneCDrevets,JonathanBSavitz,TianziJiang,JingSui,VinceDCalhoun.Resting-statefunctionalnetworkconnectivityinprefrontalregionsdiffersbetweenunmedicatedpatientswithbipolarandmajordepressivedisorders.Journalofaffectivedisorders,2016,190:483-493. [34]ShengfengLiu,HaiyingWang,MingSong,LuxianLv,YueCui,YongLiu,LingzhongFan,NianmingZuo,KaibinXu,YuhuiDu,QingbaoYu,NaLuo,ShileQi,JianYang,SangmaXie,JianLi,JunChen,YunchunChen,HuaningWang,HuaGuo,PingWan,YongfengYang,PengLi,LinLu,HaoYan,JunYan,HuilingWang,HongxingZhang,DaiZhang,VinceDCalhoun,TianziJiang,JingSui.Linked4-WayMultimodalBrainDifferencesinSchizophreniainaLargeChineseHanPopulation.SchizophreniaBulletin,2018. [35]JingSui,ShileQi,TheovanErp,JuanBustillo,RongtaoJiang,DongdongLin,JessicaTurner,EswarDamaraju,AndyMayer,YueCui,ZeningFu,YuhuiDu,JiayuChen,StevenPotkin,AdrianPreda,DanielH.Mathalon,JudithFord,JamesVoyvodic,BryonA.Mueller,AysenilBelger,SarahC.McEwen,O'LearyDanielS,AgnesMcMahon,TianziJiang,andVinceCalhoun.Multimodalneuromarkersinschizophreniaviacognition-guidedMRIfusion.NatureCommunications.2018,9(1),3028 [36]EvaMennigen,SusannaL.Fryer,BarnalyRashidMr.EswarDamaraju,YuhuiDu,RachelL.Loewy,BarbaraK.Stuart,VinceD.Calhoun,DanielH.Mathalon,Transientpatternsoffunctionaldysconnectivityinclinicalhighriskandearly-illnessschizophreniaindividualscomparedtohealthycontrols,BrainConnectivity,2018. [37]DongrenYao,VinceDCalhoun,ZeningFu,YuhuiDu,JingSui.AnEnsembleLearningSystemfora4-WayClassificationofAlzheimer’sDiseaseandMildCognitiveImpairment.Journalofneurosciencemethods,2018. [38]JiayuChen,BarnalyRashid,QingbaoYu,JingyuLiu,DongdongLin,YuhuiDu,JingSui,VinceDCalhoun.VariabilityinRestingStateNetworkandFunctionalNetworkConnectivityAssociatedWithSchizophreniaGeneticRisk:APilotStudy.Frontiersinneuroscience,2018,12:114. [39]ElizabethOsuch,ShuangGao,MichaelWammes,JeanTheberge,PeterWilliamson,RichardNeufeld,YuhuiDu,JingSui,VinceCalhoun.Complexityinmooddisorderdiagnosis:fMRIconnectivitynetworkspredictedmedication-classofresponseincomplexpatients.ActaPsychiatricaScandinavica.2018 [40]QingbaoYu,LeiWu,DavidABridwell,ErikBarryErhardt,YuhuiDu,HaoHe,JiayuChen,PengLiu,JingSui,GodfreyPearlson,VinceDCalhoun.BuildinganEEG-fMRImulti-modalbraingraph:aconcurrentEEG-fMRIstudy.FrontiersinHumanNeuroscience.2016,SCI.doi:10.3389/fnhum.2016.00476. [41]XingMeng,RongtaoJiang,DongdongLin,JuanBustillo,ThomasJones,JiayuChen,QingbaoYu,YuhuiDu,YuZhang,TianziJiang,JingSui,VinceDCalhoun.PredictingindividualizedclinicalmeasuresbyageneralizedpredictionframeworkandmultimodalfusionofMRIdata.NeuroImage,2017,145,218–229. [42]DongdongLin,JiayuChen,StefanEhrlich,JuanRBustillo,NoraPerrone-Bizzozero,EstherWalton,VincentPClark,Yu-PingWang,JingSui,YuhuiDu,BengCHo,CharlesSSchulz,VinceDCalhoun,JingyuLiu.Cross-TissueExplorationofGeneticandEpigeneticEffectsonBrainGrayMatterinSchizophrenia,ShizophreniaBulletin,2018,44,443-452. [43]HaoHe,JingSui,YuhuiDu,QingbaoYu,DongdongLin,WayneC.Drevets,JonathanB.SavitzJianYang,TeresaA.Victor,VinceD.Calhoun.Co-alteredfunctionalnetworksandbrainstructureinunmedicatedpatientswithbipolarandmajordepressivedisorders.BrainStructureandFunction,2017,222(9):4051-4064. [44]ShileQi,VinceD.Calhoun,TheoG.M.vanErp,JuanBustillo,EswarDamaraju,JessicaAnnTurner,YuhuiDu,etal.MultimodalFusionwithReference:SearchingforJointNeuromarkersofWorkingMemoryDeficitsinSchizophrenia.IEEETransactionsonMedicalImaging.2017,37(1):93-105. [45]RongtaoJiang,ChristopherCAbbott,TianziJiang,YuhuiDu,etal.SMRIBiomarkersPredictElectroconvulsiveTreatmentOutcomes:AccuracywithIndependentDataSets.Neuropsychopharmacology.2018,43(5),1078. [46]QingbaoYu,YuhuiDu,JiayuChen,HaoHe,JingSui,GodfreyPearlson,VinceDCalhoun.Comparingbraingraphsinwhichnodesareregionsofinterestorindependentcomponents:asimulationstudy.JournalofNeuroscienceMethods.2017,291:61-68. [47]DongmeiZhi,VinceDCalhoun,LuxianLv,XiaoHongMa,QingKe,YongfengYang,XiaoYang,MiaoPan,ShileQi,RongtaoJiang,YuhuiDu,QingbaoYuandJingSui.AberrantDynamicFunctionalNetworkConnectivityandGraphPropertiesinMajorDepressiveDisorder.FrontiersinPsychiatry|MoodandAnxietyDisorders.2018. [48]RongtaoJiang,ShileQi,YuhuiDu,WeizhengYan,VinceDCalhoun,TianziJiang,JingSui.Predictingindividualizedintelligencequotientscoresusingbrainnetome-atlasbasedfunctionalconnectivity.2017IEEE27thInternationalWorkshoponMachineLearningforSignalProcessing(MLSP),2017. [49]MustafaSalman,YuhuiDu*,VinceCalhoun*.IdentifyingfMRIDynamicConnectivityStatesUsingAffinityPropagationClusteringMethod:ApplicationtoSchizophrenia.The42ndIEEEInternationalConferenceonAcoustics,SpeechandSignalProcessing,2017.904-908 [50]MustafaSSalman,YuhuiDu*,EswarDamaraju,VinceDCalhoun*.GroupinformationguidedICAshowsmoresensitivitytogroupdifferencesthandual-regression.IEEEInternationalSymposiumonBiomedicalImaging,2017.362-365. [51]JiangDi,YuhuiDu,andYongFan.fMRIAlignmentBasedonLocalFunctionalConnectivityPatterns.SPIEMedicalImaging,831415-831415-8,2012. [52]ShileQi,VinceCalhoun,TheoG.M.vanErp,EswarDamaraju,JuanBustillo,JessicaTurner,YuhuiDu,DanielH.Mathalon,JudithM.Ford,JamesVoyvodic,BryonMueller,AysenilBelger,SarahMcEwen,StevenG.Potkin,AdrianPreda,FBIRN,TianziJiang,JingSui.SupervisedMultimodalFusionandItsApplicationinSearchingJointNeuromarkersofWorkingMemoryDeficitsinSchizophrenia.The38thAnnualInternationalConferenceoftheIEEEEngineeringinMedicineandBiologySociety(EMBS),2016. [53]HaoHe,JuanBustillo,YuhuiDu,QingbaoYu,ThomasR.Jones,TianziJiang,VinceD.Calhoun,JingSui.RestingfMRImeasuresareassociatedwithcognitivedeficitsinschizophreniaassessedbytheMATRICSconsensuscognitivebattery.Proc.SPIE9417,MedicalImaging2015:BiomedicalApplicationsinMolecular,Structural,andFunctionalImaging,2015,94171V-94171V-8. [54]JingSui,EduardoCastro,HaoHe,DavidBridwell,YuhuiDu,GodfreyDPearlson,TianziJiang,VinceDCalhoun.CombinationofFMRI-SMRI-EEGdataimprovesdiscriminationofschizophreniapatientsbyensemblefeatureselection.The36thAnnualInternationalConferenceoftheIEEEEngineeringinMedicineandBiologySociety(EMBS),2014,3889-3892.