李凌君 - 河南师范大学 - 化学化工学院

个人简介

河南省教授，化学生物学研究所所长，河南省科技创新杰出青年，高校科技创新人才支持计划获得者，河南省教育厅学术技术带头人，入选河南省高层次人才国际化培养计划。主要从事化学生物学和生物有机化学研究。主持国家自然科学基金4项，第一或通讯作者在JACS等SCI期刊发表学术论文20余篇，论文被引用1000余次，授权发明专利8件，受邀在国际和全国学术会议做大会报告和邀请报告6次，研究成果被国内外学术媒体连续采访报道。教育与研究经历： 1997,09- 2001,07河南师范大学化学与环境科学学院化学教育专业理学学士 2001,09 - 2004,07河南师范大学化学与环境科学学院有机化学专业理学硕士 2004,08 -2007,07 北京大学药学院，天然产物与仿生药物国家重点实验室，化学生物学专业博士 2009,12-2010,06美国内华达大学医学院，生理学系，NIH访问学者 2011, 12- 2012.12美国Scripps研究所，化学生物学专业博士后 2007,07-至今河南师范大学化学与化工学院副教授，教授

研究领域

核酸化学生物学，生物有机化学，高通量化学生物学方法

近期论文

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Feldman, Aaron W.;† Dien, Vivian T.;† Karadeema, Rebekah J.; Fischer, Emil C.; You, Yanbo; Chen, Jason S; Li, Lingjun.*; Romesberg, Floyd. E.* Optimization of Replication, Transcription, and Translation in a Semi-Synthetic Organism. J. Am. Chem. Soc. 2019, 141 (27), 10644-10653. (IF = 14.357) Li, Lingjun; Degardin, Melissa; Lavergne, Thomas; Malyshev, Denis A.; Dhami, Kirandeep; Ordoukhanian, Phillip; Romesberg, Floyd E.* Natural-like Replication of an Unnatural Base Pair for the Expansion of the Genetic Alphabet and Biotechnology Applications. J. Am. Chem. Soc. 2014, 136 (3), 826-829. (IF = 14.357) Zhang, Yorke; Lamb, Brian M; Feldman, Aaron W; Zhou, Anne Xiaozhou; Lavergne, Thomas; Li, Lingjun; Romesberg, Floyd E*. A semisynthetic organism engineered for the stable expansion of the genetic alphabet. Proc. Natl. Acad. Sci. U S A 2017, 114 (6), 1317-1322. (IF = 9.674) Zhu, Anlian; Li, Lingjun;* Zhang, Chi; Shen Yutan; Tang, Mingjie, Bai, Lili; Du, Chunyan; Zhang, Suojiang; Wang, Jianji* An Integrated High-throughput Strategy Enables the Discovery of Multifunctional Ionic Liquids for Sustainable Chemical Processes. Green Chem. 2019, 21(2), 307-313. (IF = 9.405) Zhu, Anlian;* Xing, Xiaofang; Wang, Shilei; Yuan, Donghe; Zhu, Gongmin; Geng, Mingwei; Guo, Yuanyang; Zhang, Guisheng; Li, Lingjun* Multi-component Syntheses of Diverse 5-Fluoroalkyl-1,2,3-triazoles Facilitated by Air Oxidation and Copper Catalysis. Green Chem. 2019, 21 (12), 3407- 3412 (IF = 9.405) Li, Lingjun*; Ding, Shengqiang; Yang, Yanping; Zhu, Anlian; Fan, Xincui; Cui, Mengchao*; Chen, Changpo; Zhang, Guisheng*. Multicomponent Aqueous Synthesis of Iodo-1,2,3-triazoles: Single-Step Models for Dual Modification of Free Peptide and Radioactive Iodo Labeling. Chemistry-A European Journal 2017, 23 (5), 1166-1172. (IF = 5.160) Li, Lingjun;* Huang, Shenlong; Shang, Tongpeng, Zhang, Bo; Guo, Yuanyang; Zhu, Gongming; Zhou, Demin;* Zhang, Guisheng;* Zhu, Anlian; Zhang Lihe. Medium Rings Bearing Bitriazolyls: Easily Accessible Structures with Superior Performance as Cu Catalyst Ligands. J. Org. Chem. 2018, 83(21), 13166−13177. (IF = 4.85) Lavergne, T.; Lamichhane, R.; Malyshev, D. A.; Li, Zhengtao Li; Li, Lingjun; Sperling, Edit ; Williamson, James R.; Millar, David P.; Romesberg. Floyd E. FRET Characterization of Complex Conformational Changes in a Large 16S Ribosomal RNA Fragment Site-Specifically Labeled Using Unnatural Base Pairs. ACS Chem. Biol., 2016. 11(5), 1347−1353. (IF = 5.331)