当前位置: X-MOL首页全球导师 国内导师 › 郭海明

个人简介

教育与研究经历 1993.09-1997.06 河南师范大学化学系,化学专业,理学学士 1997.09-2000.06 河南师范大学化学与环境科学学院,有机化学专业,理学硕士(导师:渠桂荣教授) 2003.09-2006.06 中国科学院成都有机所,有机化学专业,理学博士(导师:蒋耀忠研究员龚流柱教授) 1998.09-2000.07 河南师范大学化学与环境科学学院,兼职96级本科生辅导员 2000.07-2003.08 河南师范大学化学与环境科学学院,助教,兼职2000级本科生辅导员 2003.09-2008.02 河南师范大学化学与环境科学学院,讲师,硕士生导师(2006.09) 其中,2007.04-2008.07 美国Scripps研究所,分子生物学专业,博士后 2008.03-2013.02 河南师范大学化学与环境科学学院,副教授,博士生导师(2010.12) 2013.03-2016.12, 河南师范大学化学化工学院,教授,博士生导师 2016.12-今, 河南师范大学化学化工学院,二级教授,博士生导师

研究领域

(1)不对称合成 (2)核苷的选择性结构修饰 (3)分子的荧光标记与荧光识别 (4)核苷类药物的设计与合成

近期论文

查看导师新发文章 (温馨提示:请注意重名现象,建议点开原文通过作者单位确认)

Tao Wei, Han-Le Wang, Yin Tian*, Ming-Sheng Xie*, Hai-Ming Guo*, Enantioselective construction of stereogenic-at-sulfur(IV) centres via catalytic acyl transfer sulfinylation, Nature Chemistry (2024) early view. Tao Wei, Ming-Sheng Xie *, Hai-Ming Guo*, Construction of thioglycoside bonds via an asymmetric organocatalyzed sulfa-Michael/aldol reaction: access to 4′-thionucleosides, Chem. Commun., 2024, 60, 5018-5021. (Chemical Communications HOT Articles 2024) Ru-Lin Luo, Xiao-Bing Wang, Ming-Sheng Xie*, Hai-Ming Guo *, Catalytic asymmetric ring-opening of aminocyclopropanes with oxygen nucleophiles: access to chiral γ-amino acid derivatives, Org. Chem. Front., 2024, 11, 1817-1823. Ting-Ting Yang, Yun-Qiao Zhang, Ming-Sheng Xie, Yin Tian*, Dong-Chao Wang*, Hai-Ming Guo*, Dearomative [2 + 1] Spiroannulation of Bromophenols with Electron-Deficient Alkenes, J. Org. Chem., 2024, Articles ASAP (Article). Dan Liu, Zhen-Cao Shu, Zhihan Zhang, Ze-Tian Wang, Liang Wang, Ming-Sheng Xie*, Hai-Ming Guo, Liang-Qiu Lu*, Wen-Jing Xiao*, Asymmetric Cascade Cyclization of Enynamides with Photogenerated Ketenes via Relay Gold and N-Oxide Catalysis, ACS Catalysis, 2024, 14, 3, 1741-1749. Qian Zhang*, Tian-Jiao Yue, Shi-Jie Jiang, Hai-Ming Guo*, Linking Nitrogen-Rich Pillar[5]arene to Hyper-Cross-Linked Polymers for Efficient and Simultaneous Capture of Iodine and Methyl Iodide, ACS Applied Polymer Materials, 2024, 4, 5507-5515. Hai-Xia Wang, Chun Yang, Bai-Yu Xue, Ming-Sheng Xie*, Yin Tian*, Cheng Peng, Hai-Ming Guo*, Design of C1-symmetric tridentate ligands for enantioselective dearomative [3 + 2] annulation of indoles with aminocyclopropanes, Nat Commun, Article number: 2270 (2023). Xing-Yu Wang, Xiao-Bing Wang, Yin Tian*, Cheng Peng, Ming-Sheng Xie*, Hai-Ming Guo*, Cobalt-Catalyzed Asymmetric Dearomative [3 + 2] Annulation of Quinolines, Isoquinolines, and Pyridines, ACS Catal. 2023, 13, 17, 11528-11540. Dong-Chao Wang*, Jia-Hui Liu, Yu-Qing Guan, Hai-Ming Guo*, Dearomative [4 + 2] Annulation of Electron-Poor N-Heteroarenes with Azoalkenes for Access to Polycyclic Tetrahydro-1,2,4-triazines, Org. Lett. 2023, 25, 3543-3547. Yang-Guang Chen, Heng-Bin Yu, Yin Tian*, Cheng Peng, Ming-Sheng Xie*, Hai-Ming Guo*, ArPNO-Catalyzed Acylative Dynamic Kinetic Resolution of 3-Hydroxyphthalides: Access to Enantioenriched Phthalidyl Esters, Org. Lett. 2023, 25, 5585-5590. Bai-Yu Xue, Chen-Ying Hou, Xiao-Bing Wang, Ming-Sheng Xie*, Hai-Ming Guo*, Asymmetric synthesis of 7-membered-ring-bridged 3,4-fused tricyclic indoles via Friedel–Crafts alkylation/annulation, Org. Chem. Front., 2023, 1910-1914. Lei Cao, Xing-Ping Zhang, Ming-Sheng Xie*, Hai-Ming Guo, Cu-Catalyzed N-Arylation of Prolinamides: Access to Enantioenriched DMAP Analogues and Its Application in Black Rearrangement, J. Org. Chem. 2023, 88, 1, 341–346 Qi-Liang Yang*, Yi-Rui Luo, Rong-Yi Xu, Bei-Ning Zhang, Yan-Ni Zhang, Hai-Ming Guo*, Ruthenium(II)-Catalyzed [4 + 2] Electro-Oxidative Annulation of C6-Arylpurines/Purine Nucleosides, Organic Letters, 2023, 6796-6801. Qi-Ying Zhang*, Lu-Xin Li, Song-Lin Wang, Jing Ma, Hai-Ming Guo*, Electrochemically-Driven Organocatalytic Enantioselective Oxidative Coupling of Tetrahydroisoquinolines and Acrylaldehyde,Adv. Synth. Catal. 2023, 3455-3460. Sai-Ya Lian, Ning Li, Yin Tian*, Cheng Peng, Ming-Sheng Xie*, Hai-Ming Guo, Reversal of Enantioselectivity for the Desymmetrization of meso-1,2-Diols Catalyzed by Pyridine-N-oxides, J. Org. Chem.2023, 13771-13781. Qi-Ying Zhang,* Hai-Yang Wang, Songlin Wang, Jing Ma, Hai-Ming Guo*, Kinetic resolution of heterobiaryl N-oxides by asymmetric C–H olefination: an expeditious access to (R)-QUINAP, Org. Chem. Front., 2023, 5210-5215. Ya-Ping Wang, Xing-Ping Zhang, Ming-Sheng Xie*, Hai-Ming Guo*, Cobalt(II)-Catalyzed Enantioselective Propargyl Claisen Rearrangement: Access to Allenyl-Substituted Quaternary β-Ketoesters, Organic Letters, 2023, 25, 39, 7105-7109. Qi-Liang Yang*, Wan-Wan Li, Zhong-Xu Zhang, Han-Meng Zhang, Xian-Jia Li, Hai-Ming Guo*, Electrocatalytic oxidative C–H cycloamination towards tricyclic [1,2,4]triazolo-[3,4-i]purine nucleosides mediated by bromide ions, Org. Chem. Front., 2023, 5369-5374.(2023 Organic Chemistry Frontiers HOT articles) Qi-Liang Yang∗, Ping-Ping Lei‡, Er-Jun Hao, Bei-Ning Zhang, Hong-Hao Zhou, Wan-Wan Li, Hai-Ming Guo∗, Oxidative C–H Sulfonylation of Hydrazones Enabled by Electrochemistry, SynOpen, 2023; 07(04): 535-547 Yang-Guang Chen, Ying Hu, Jia-Yi Liu, Ming-Sheng Xie*, Hai-Ming Guo*, Pyridine-N-oxide catalyzed acylative desymmetrization of bisphenols: access to P-stereogenic phosphinates with low catalyst loadings, Org. Chem. Front., 2023, 6140-6145. Ming-Sheng Xie*, Meng Shan, Ning Li, Yang-Guang Chen, Xiao-Bing Wang, Xuan Cheng, Yin Tian*, Xiao-Xia Wu, Yun Deng, Gui-Rong Qu, and Hai-Ming Guo*, Chiral 4-Aryl-pyridine-N-oxide Nucleophilic Catalysts: Design, Synthesis, and Application in Acylative Dynamic Kinetic Resolution, ACS Catal. 2022, 12, 877–891。 Hai-Xia Wang, Zhi-Hao Li, Wan-Wan Li,Gui-Rong Qu,Qi-Liang Yang*, Hai-Ming Guo*, Electrochemically driven oxidative C–H/N–H cross-coupling reactions of cyclic sulfamidate imines with primary anilines and secondary amines, Green Chem., 2022, 24, 8377-8385. Xiao-Bing Wang, Yin Tian, Li Zhou, Ming-Sheng Xie*, Gui-Rong Qu, and Hai-Ming Guo, Rational Design of Chiral Tridentate Ligands: Bifunctional Cobalt(II) Complex/Hydrogen Bond for Enantioselective Michael Reactions, Org. Lett. 2022, 24, 21, 3861–3866. Qi-Liang Yang*, Ying Liu, Yi-Rui Luo, Zhi-Hao Li, Hong-Wei Jia, Ya-Bo Fu, Gui-Rong Qu, Hai-Ming Guo*, Rhodium(III)-Catalyzed Synthesis of Diverse Fluorescent Polycyclic Purinium Salts from 6-Arylpurine Nucleosides and Alkynes, Org. Lett.2022, 24, 23, 4234–4239. Dong-Chao Wang*, Pan-Pan Wu, Pei-Yu Du, Gui-Rong Qu, Hai-Ming Guo*, Highly Diastereoselective Synthesis of Oxindoles Containing Vicinal Quaternary and Tertiary Stereocenters by a Domino Heck/Decarboxylative Alkynylation Sequence, Org. Lett.2022, 24, 23, 4212–4217. Meng-Cheng Zhang, Dong-Chao Wang*, Hai-Ting Wang, Gui-Rong Qu, Hai-Ming Guo*, Highly Chemoselective Synthesis of Purino[3,2-c]oxazoles via the Asymmetric Dearomative [3+2] Cycloaddition of Purines with Donor–Acceptor Oxiranes, Org. Lett. 2022, 24, 41, 7527-7532. Qi-Liang Yang*, Ying Liu, Lei Liang, Zhi-Hao Li, Gui-Rong Qu, and Hai-Ming Guo*, Facilitating Rh-Catalyzed C–H Alkylation of (Hetero)arenes and 6-Arylpurine Nucleosides (Nucleotides) with Electrochemistry, J. Org. Chem. 2022, 87, 9, 6161-6178. Kai-Ge Chen, Hao Lu, Yi-Ming Zhou, Xiao-Long Wan, Hao-Yang Wang, Zhen-Jiang Xu*, Hai-Ming Guo*, Chi-Ming Che*,Fe-BPsalan Complex-Catalyzed Asymmetric [4 + 2] Cycloaddition of Cyclopentadiene with α,β-Unsaturated Heterocycles, J. Org. Chem.2022, 87, 13, 8289–8302. Meng-Cheng Zhang, Dong-Chao Wang*, Gui-Rong Qu, Hai-Ming Guo*, Catalytic asymmetric synthesis of chiral thiohydantoins via the domino cyclization reaction of β,γ-unsaturated α-ketoesters and N,N′-dialkylthiourea, Org. Chem. Front., 2022, 9, 4358-4364 Hai-Xia Wang, Mi-Mi Zhang, Ming-Sheng Xie*, Hai-Ming Guo*, Lewis Acid Catalyzed (3+2)-Cycloadditions of Chiral Pyrimidinyl-Substituted Cyclopropanes with Nitrosoarenes or Silyl Enol Ethers, Eur. J. Org. Chem. 2022, e202200604. Min Yang, Yu-Lin Gao, Ming-Sheng Xie*, Hai-Ming Guo*, ArPNO-catalyzed acylative kinetic resolution of tertiary alcohols: access to 3-hydroxy-3-substituted oxindoles, Org. Biomol. Chem., 2022, 20, 6351-6355. Qi-Liang Yang*, Rui-Cong Ma, Zhi-Hao Li, Wan-Wan Li, Gui-Rong Qu, Hai-Ming Guo*, Electrochemically-initiated intramolecular 1,2-amino oxygenation of alkynes: facile access to formyl- and acyl-substituted indolizines, Org. Chem. Front., 2022, 9, 4990-4997. Qi-Ying Zhang*, Pei-Xian Lu, Song-Lin Wang, Lu-Xin Li, Gui-Rong Qu, Hai-Ming Guo*, Electrochemical Enantioselective Dihydroxylation Reaction of N-Alkenyl Nucleobases for the Construction of Chiral Acyclic Nucleosides, Org. Chem. Front., 2022, 9, 4818-4822. Dong-Chao Wang*, Ting-Ting Yang, Gui-Rong Qu, Hai-Ming Guo*, Substrate-Dependent Regioselectivity: Pd/PTC Cooperatively Catalyzed Domino Heck/Allylation of Allenamides with α-Carbon of Carbonyl Compounds, J. Org. Chem., 2022, 87, 21, 14284-14298. Lei Liang*, Yue-Hui Wang, Chen Li, Hua-Jie Wang, Qi-Liang Yang, Chang-Gong Li, Gui-Rong Qu, Hai-Ming Guo, Hong-Ying Niu*, Regioselective and late-stage polyfluoroarylation of arenes with diverse fluoroaryl nucleophiles via Pd-catalysis, Org. Chem. Front., 2022, 9, 5832-5839.

推荐链接
down
wechat
bug