个人简介

Ph.D. 1984, Yale University

研究领域

Mechanistic Organic Chemistry

Unraveling the mechanism of chemical reactions often requires a detailed understanding of the role of potential reaction intermediates. These intermediates can be quite difficult to characterize because they are often unstable, highly reactive and short-lived. Professor Goodman's research goals involve the experimental challenge of preparing such reactive intermediates and accurately describing their physical and chemical properties (structure, energetics and kinetics). Radicals, biradicals, carbenes, and ion radicals are all highly reactive species that have been postulated as reactive intermediates in organic reactions. Stereochemistry, effects and kinetics are all diagnostic methods commonly employed. In addition, several complimentary time-resolved experimental techniques, pico- and nanosecond absorption spectroscopy and pulsed time-resolved photoacoustic calorimetry are used. Photoacoustic calorimetry is a new technique that effectively listens to chemical reactions. The sound waves can be used to determine the dynamics (10 ns - 50 ms) and energetics of reactive intermediates. The experimental thermochemical and dynamic information can provide valuable mechanistic insight into their intermediacy in chemical reactions.

近期论文

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She, C. X., McGarrah, J. E., Lee, S. J., Goodman, J. L., Nguyen, S. T., Williams, J. A. G., Hupp, J. T. "Probing Exciton Localization/Delocalization: Transient dc Photoconductivity Studies of Excited States of Symmetrical Porphyrin Monomers, Oligomers, and Supramolecular Assemblies," J. Phys. Chem. A. 2009, 113, 8182. Ikeda, H., Hoshi, Y., Namai, H., Tanaka, F., Goodman, J. L. and Mizuno, K. "Evidence for significant through-space and through-bond electronic coupling in the 1,4-diphenylcyclohexane-1,4-diyl radical cation gained by absorption spectroscopy and DFT calculations," Chemistry-A European Journal 2007, 13, 9207. Al-Kaysi, R. O., Goodman J. L. "Bond-Coupled Electron Transfer Processes: Cleavage of Si-Si Bonds," J. Am. Chem. Soc. 2005, 127, 1620. Hoshi, Y., Ikeda, H., Goodman, J. L., Miyashi, T. "Substituent Effects on the Absorption Spectra of 1,4-Diarylcyclohexane-1,4-diyl and 1,3-Diarylcyclohexane-1,3-diyl Radical Cations: Spectroscopic Evidence and Theoretical Explanation for Through-Space and Through-Bond Electronic Couplings," J. Am. Chem. Soc. 2003, submitted. Wang Y. S, Luttrull D. K., Dinnocenzo J. P., Goodman J. L., Farid S., Gould I.R. "Associative Return Electron Transfer. A Bond-coupled Electron Transfer in the Photoreactions of Cyclopropylamines," Photochemical & Photobiological Sciences 2003, 2, 1169-1176. Ikeda, H., Akiyama, K., Takahashi, Y., Nakamura, T., Ishizaki, S., Shiratori, Y., Ohaku, H., Goodman, J. L., Houmam, A., Wayner, D. D. M., Tero-Kubota, S., Miyashi, T. "Spectroscopic and Calorimetric Studies on the Mechanism of Methylenecyclopropane Rearrangements Triggered by Photoinduced Electron Transfer," J. Am. Chem. Soc. 2003, 125, 9147. Gould, I.R., Boiani, J. A., Gaillard, E. B., Goodman, J. L., Farid, S. "Intersystem Crossing in Charge Transfer Excited States," J. Phys. Chem. A 2003, 107, 3515. Goodman, J. L. "Photoacoustic Calorimetry of Carbenes," in Advances in Carbene Chemistry, Brinker, U. ed., Elsevier, Amsterdam, 2001. Cuppoletti, A., Dinnocenzo, J. P., Goodman, J. L., Gould, I. R. "Bond-Coupled Electron Transfer Reactions: Photoisomerization of Norbornadiene to Quadricyclane," J. Phys. Chem. A 1999, 103, 11253.