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个人简介

崔艳华,博士,教授,博士生导师,医学与健康学院食品营养与健康系主任。主要研究方向为分子生物学、基因工程与食品生物技术、食品质量与生物安全。主要从事益生菌代谢调控研究,研究益生菌有益代谢产物的合成机制、分子定向选育优良益生菌菌株等。主持承担了国家自然科学基金(面上项目)、国家自然科学基金(青年项目)等10余项,参与国家重点研发项目、国家自然科学基金等项目10余项。在Trends in Food Science and Technology, Carbohydrate Polymers, Frontiers in Microbiology等国际期刊发表SCI收录论文30余篇,EI收录论文7篇,其中2篇入选ESI "Highly-Cited Paper (last ten years)"。 工作经历 202110- 哈尔滨工业大学医学与健康学院 教授 博士生导师 201512- 哈尔滨工业大学化工学院 教授 博士生导师 201505-201512 哈尔滨工业大学化工学院 副教授 博士生导师 201304- 哈尔滨工业大学食品科学与工程学院 博士生导师 201109-201209 加拿大圭尔夫大学食品科学系Visiting Professor 201009-201505 哈尔滨工业大学食品科学与工程学院 副教授 200905- 哈尔滨工业大学食品科学与工程学院 硕士生导师 200710-201107 哈尔滨工业大学化学工程与技术博士后流动站 200607-201009 哈尔滨工业大学食品科学与工程学院 讲师 教育经历 200309-200607, 中国农业大学生物学院微生物与免疫学系,农业生物技术国家重点实验室,获博士学位 200107-200307, 中国农业科学院作物科学研究所,农业部作物种质资源与生物技术重点开放实验室,硕士论文研究 200009-200307,东北农业大学,获硕士学位 199609-200007,东北农业大学,获学士学位 荣誉称号 200711 获哈尔滨工业大学第二届青年教师教学基本功竞赛 二等奖 200907 哈尔滨工业大学本科生校级优秀毕业论文指导教师 200911 获哈尔滨工业大学第三届青年教师教学基本功竞赛 二等奖 201007 获得2009-2010年度哈尔滨工业大学食品科学与工程学院优秀共产党员称号 201101 获得哈尔滨工业大学食品科学与工程学院青年教师优秀教学课件评比 一等奖 201312 获得2012-2013年度哈尔滨工业大学食品科学与工程学院先进个人称号 201407 获 哈尔滨工业大学食品科学与工程学院先进党支部称号 201506 获哈尔滨工业大学化工学院2014-2015年度优秀班主任称号 201512 获哈尔滨工业大学2014-2015年度优秀专兼职学生工作者称号

研究领域

分子微生物学 基因工程与食品生物技术 食品质量与生物安全 主要研究方向: 益生菌代谢调控及耐酸机制研究 益生菌活性产物及调控 乳蛋白基因遗传多样性研究 食源性病原菌的检测方法与技术及致病机制研究 酶的定向改造

近期论文

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Yanhua Cui*, Xiaojun Qu. Genetic mechanisms of prebiotic carbohydrate metabolism in lactic acid bacteria: Emphasis on Lacticaseibacillus casei and Lacticaseibacillus paracasei as flexible, diverse and outstanding prebiotic carbohydrate starters. Trends in Food Science and Technology, 2021, 115, 486-499.(SCI, IF2021=16.002, TOP期刊) Zhou Yang, Cui Yanhua*, Suo Chao, Wang Qian, Qu Xiaojun. Structure, physicochemical characterization, and antioxidant activity of the highly arabinose-branched exopolysaccharide EPS-M2 from Streptococcus thermophilus CS6. International Journal of Biological Macromolecules, 2021, 192, 716-727.(SCI, IF2021=8.025, TOP期刊) Cui Yanhua*, Wang Meihong, Zheng Yankun, Miao Kai, Qu Xiaojun. The carbohydrate metabolism of Lactiplantibacillus plantarum. International Journal of Molecular Sciences, 2021, 22(24), 13452. (SCI,IF2021=6.208, TOP期刊) Tong Hu, Yanhua Cui*, Yishuang Zhang, Xiaojun Qu, Chunyu Zhao. Genome analysis and physiological characterization of four Streptococcus thermophilus strains isolated from Chinese traditional fermented milk. Frontiers in Microbiology, 2020, 11, 184.(SCI, IF2020=5.64, TOP期刊) Tong Hu, Yanhua Cui*, Xiaojun Qu. Analysis of the proteolytic system of Streptococcus thermophilus strains CS5, CS9, CS18 and CS20. International Dairy Journal, 2021, 118, 105025.(SCI, IF2021=3.572) Yuxuan Guan, Yanhua Cui*, Xiaojun Qu, Kai Jing. Safety and robustness aspects analysis of Lactobacillus delbrueckii ssp. bulgaricus LDB-C1 based on genome analysis and biological tests. Archives of Microbiology, 2021, doi.org/10.1007/s00203-021-02383-7(SCI, IF2021=2.667) Yanhua Cui*, Kai Miao, Siripitakyotin Niyaphorn, Xiaojun Qu. Production of gamma-aminobutyric acid from Lactic Acid Bacteria. International Journal of Molecular Sciences, 2020, 21(3), 995. (SCI, IF2020=5.923, TOP期刊, ESI Highly-Cited Paper) Tong Hu, Yanhua Cui*, Xiaojun Qu. Characterization and comparison of CRISPR loci in Streptococcus thermophilus. Archives of Microbiology, 2020, 202(4):695-710. (SCI, IF2020=2.552) Chao Wang, Yanhua Cui*, Xiaojun Qu. Research progress of electrotransformation in lactic acid bacteria. Journal of Microbiological Methods, 2020, 174, 105944.(SCI, IF2020=2.363) Yang Zhou, Yanhua Cui*, Xiaojun Qu. Exopolysaccharides of lactic acid bacteria: structure, bioactivity and associations. Carbohydrate Polymers, 2019, 207:317-332. (SCI, IF2019=7.182, TOP期刊) Mengyuan Hao, Yanhua Cui*, Xiaojun Qu. Analysis of CRISPR-Cas system in Streptococcus thermophilus and its application. Frontiers in Microbiology, 2018, 9:257.(SCI, IF2018=4.259, TOP期刊) Chao Wang, Yanhua Cui*, Xiaojun Qu. Identification of proteins regulated by acid adaptation two component system HPK1/RR1 in Lactobacillus delbrueckii subsp. bulgaricus. Archives of Microbiology, 2018, 200(9), 1381-1393. (SCI, IF2018=1.642) Tong Hu, Yisuang Zhang, Yanhua Cui*, Chunyu Zhao, Xu Jiang, Xirong Zhu, Yu Wang, Xiaojun Qu*. Technological properties assessment and two component systems distribution of Streptococcus thermophilus strains isolated from fermented milk. Archives of Microbiology, 2018, 200(4), 567-580. (SCI, IF2018=1.642) Chao Wang, Yanhua Cui*, Xiaojun Qu. Mechanisms and improvement of acid resistance in lactic acid bacteria. Archives of Microbiology, 2018, 200(2):195-201. (SCI, IF2018=1.642) Yanhua Cui*, Xu Jiang, Mengyuan Hao, Xiaojun Qu, Tong Hu. New advances in exopolysaccharides production of Streptococcus thermophilus. New Insights into Exopolysaccharides from Streptococcus thermophilus. Archives of Microbiology, 2017, 199:799-809. (SCI, IF2017=1.607) Yanhua Cui *, Tingting Xu, Xiaojun Qu, Tong Hu, Xu Jiang, Chunyu Zhao. New insights into various production characteristics of Streptococcus thermophilus strains. International Journal of Molecular Sciences, 2016, 17, 1701. (SCI, IF2016=3.226) Yanhua Cui*, Tong Hu, Xiaojun Qu, Zhang Lanwei, Zhongqing Ding, Aijun Dong. Plasmids from food lactic acid bacteria: Diversity, Similarity, and New Developments. International Journal of Molecular Sciences, 2015, 16(6), 13172-13202. (SCI, IF2015=3.257) Yanhua Cui, Ting Yu, Xiaojun Qu, Tong Hu, Chao Wang, Shenghua He, Ying Ma. Genetic variation in the αS1-casein of Chinese yak (Bos grunniens). European Food Research and Technology, 2014, 239(1):175-181. (SCI, IF2014=1.387) Yanhua Cui, Wei Liu, Xiaojun Qu, Zhangting Chen, Xu Zhang, Tong Liu, Lanwei Zhang. A two component system is involved in acid adaptation of Lactobacillus delbrueckii subsp. bulgaricus. Microbiological Research, 2012, 167, 253-261.(SCI, IF2012=1.993) Yanhua Cui, Binyue Liu, Xiaojun Qu, Aijun Dong, Yu Cao, Ying Ma. Detection of β-casein variants in yak (Bos grunniens) by PCR-SSCP. European Food Research and Technology, 2012, 234(3):551-556. (SCI, IF2012=1.566) Yanhua Cui, Yu Cao, Xiaojun Qu, Aijun Dong, Ying Ma. Genetic variation in the β-lactoglobulin of Chinese Yak (Bos grunniens). Journal of Genetics, 2012, 91, e44-e48. (SCI, IF2012=1.338) Yanhua Cui, Xiaojun Qu, Haimei Li, Shenghua He, Hengyu Liang, Hui Zhang, Ying Ma. Isolation of halophilic lactic acid bacteria from traditional Chinese fermented soybean paste and assessment of the isolates for industrial potential. European Food Research and Technology, 2012, 234(5), 797-806. (SCI, IF2012=1.566) Yanhua Cui, Chao Zhang, Yunfeng Wang, John Shi, Lanwei Zhang, Zhongqing Ding, Xiaojun Qu and Hongyu Cui. Review: Class IIa Bacteriocins: Diversity and New Developments. International Journal of Molecular Sciences, 2012, 13(12), 16668-16707. (SCI, IF2012=2.464) Yanhua Cui, Ran Tu, Lixian Wu,Yuanyuan Hong, and Sanfeng Chen. A hybrid two-component system protein from Azospirillum brasilense Sp7 was involved in chemotaxis. Microbiological Research, 2011, 166(6):458-467.(SCI, IF2011=2.308)

学术兼职

黑龙江省生物工程学会理事 教育部学位中心学位论文函评专家 国家自然科学基金、中国博士后科学基金等项目函评专家 Carbohydrate Polymers, International Journal of Food Microbiology,Journal of Agricultural and Food Chemistry,Frontiers in Microbiology, Journal of Dairy Science,International Journal of Biological Macromolecules等国际期刊审稿人

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