宋岚 - 湖南中医药大学

研究领域

从事肺损伤发病机制及防治研究，擅长分子生物学实验技术，对细胞凋亡和相关基因克隆进行了系列研究。近年来致力于转录因子的生物学功能研究，首次发现FoxA1在急性肺损伤肺组织和内毒素、炎症因子、氧化应激刺激的肺泡Ⅱ型上皮细胞中表达显著升高，并通过直接调控bcl-2、UCP2等多个下游基因表达在ALI中发挥重要生物学功能。

近期论文

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1.Release of heat shock protein 70 and the effects of extracellular heat shock protein 70 on the production of IL-10 in fibroblast-like synoviocytes. Cell Stress Chaperones. 2008 13(3):365-73. SCI收录 2.ADRENALINE INHIBITED CELL PROLIFERATION AND REGULATED EXPRESSION OF TGF-BETA1 AND BFGF IN CULTURED HUMAN HYPERTROPHIC SCAR FIBROBLASTS VIA α-RECEPTOR. EXCLI Journal, 2008;7:1-12. SCI收录 3.A role for forkhead box A1 in acute lung injury. Inflammation. 2009 Oct;32(5):322-32. SCI收录 4.Up-regulation of the HSP72 by Foxa1 in MCF-7 human breast cancer cell line. Biochem Biophys Res Commun. 2009 Aug 14;386(1):30-4. SCI收录 5.Role of Foxa1 in regulation of bcl2 expression during oxidative-stress-induced apoptosis in A549 type II pneumocytes. Cell Stress Chaperones. 2009 Jul;14(4):417-25. SCI收录 6.Overexpression of MIP2, a novel WD-repeat protein, promotes proliferation of H9c2 cells. Biochem Biophys Res Commun.2010 Mar 19;393(4):860-3. SCI收录 7.The microRNA miR-17 regulates lung FoxA1 expression during lipopolysaccharide-induced acute lung injury. Biochem Biophys Res Commun. 2014，445(1):48-53. SCI收录 8.Forkhead box protein A1 inhibits the expression of uncoupling protein 2 in hydrogen peroxide-induced A549 cell line. Cell Stress Chaperones. January 2014, 19(1): 53-60. SCI收录 9.Novel mutation in the STAT3 gene in a Chinese boy with hyper-immunoglobulin E syndrome. J Dermatol.2014 Jul;41(7):658-9. SCI收录 10.FoxA1在急性肺损伤肺泡Ⅱ型上皮细胞凋亡中的作用. 微循环学杂志,2009,(4): 102. 11.环氧交联去细胞牛颈静脉带瓣管道的血液相容性研究. 中国胸心血管外科临床杂志，2011 ,18 (4):311-317. 12.雷公藤甲素对宫颈癌Hele细胞增殖的抑制作用. 肿瘤药学，2011,1(1). 13.原花青素交联去细胞牛颈静脉带瓣管道的实验研究. 现代生物医学进展，2012,12(30):5831-5835. 14.早期大剂量乌司他丁治疗急性肺挫伤的疗效观察.现代生物医学进展,2013,(13)32:6276-7279.