杨光 - 河南大学 - 抗体药物开发技术国家地方联合工程实验室

个人简介

1998年毕业于北京大学，获学士学位；2003年毕业于军事医学科学院，获博士学位。获得奖励 2008年获得北京市科技进步二等奖（排名2） 2007年入选北京市科技新星 2013年当选军事医学科学院首届十大杰出青年 2013年荣立三等功

研究领域

1，金葡菌感染与免疫的应用基础研究 2，自身免疫病自身抗原鉴定及与发病的关联 3，治疗性抗体研发

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1.Jiang XX, Liu Y, Li H, Gao Y, Mu R, Guo J, Zhang J, Yang YM, Xiao F, Liu B, Wang C, Shen B, Chen SY, Li Z, Yang G*. MYSM1/miR-150/FLT3 inhibits B1a cell proliferation.Oncotarget. 2016 Aug 31. doi: 10.18632/oncotarget.11738. 2.Liu Y, Mu R, Gao Y, Dong J, Zhu L, Ma Y, Li YH, Zhang HQ, Han D, Zhang Y, McInnes I, Zhang J, Shen B, Yang G*, Li ZG. A cytomegalovirus peptide-specific antibody alters natural killer cell homeostasis and is shared in several autoimmune diseases. Cell Host microbe. Cell Host Microbe. 2016 Mar 9;19(3):400-408. 3.Liu Y, Feng J, Lu Q, Zhang X, Gao Y, Yan J, Mu C, Hei Y, Lv M, Han G, Chen G, Jin P, Hu W, Shen B, Yang G*. MAE4, an eLtaS monoclonal antibody, blocks Staphylococcus aureus virulence. Sci Rep. 2015 Nov 24;5:17215. doi: 10.1038/srep17215. 4.Yan J, Liu Y, Gao Y, Dong J, Mu C, Li D, Yang G*. RNAIII suppresses the expression of LtaS via acting as an antisense RNA in Staphylococcus aureus. J Basic Microbiol. 2014 Oct 3. doi: 10.1002/jobm.201400313. 5.Gong J, Li D, Yan J, Liu Y, Li D, Dong J, Gao Y, Sun T, Yang G*. The accessory gene regulator (agr) controls Staphylococcus aureus virulence in a murine intracranial abscesses model. Braz J Infect Dis. 2014 May 13. pii: S1413-8670(14)00093-2. doi: 10.1016/j.bjid.2014.03.005. 6.Zhu WW, Kang L, Gao YP, Hei Y, Dong J, Liu Y, Xiao LH, Yang G*. Expression level of valosin containing protein is associated with prognosis of primary orbital MALT lymphoma. Asian Pac J Cancer Prev. 2013;14(11):6439-43. 7.Liu Y, Dong J, Mu R, Gao Y, Tan X, Li Y, Li Z, Yang G*. MicroRNA-30a promotes B cell hyperactivity in patient with SLE by direct interaction with LYN. Arthritis Rheum. 2013 Jun;65(6):1603-11. 8.Gao YP, Dong J, Zhang X, Liu Y, Lu Q, Feng JN, Tan XR, Yang G*. A Novel Peptide Can Mimic Extracellular Fibrinogen-Binding Protein to Block the Activation of Complement System. Cell Biochem Biophys. 2013 Jul;66(3):753-7. 9.Liu Y, Hei Y, Shu Q, Dong J, Gao Y, Fu H, Zheng X, Yang G*. VCP/p97, Down-Regulated by microRNA-129-5p, Could Regulate the Progression of Hepatocellular Carcinoma. PLoS One. 2012;7(4):e35800. Epub 2012 Apr 20. 10.Mu C, Liu Y, Gao Y, Dong J, Lu Q, Tan X, Yang G*. The expression of LytM is down-regulated by RNAIII in Staphylococcus aureus. Journal of Basic Microbiol. 2012 May 14. doi: 10.1002/jobm.201100426. 11.Liu Y, Dong J, Wu N, Gao Y, Zhang X, Mu C, Shao N, Fan M, Yang G*.The production of extracellular proteins is regulated by ribonuclease III via two different pathways in Staphylococcus aureus. PLoS One. 2011;6(5):e20554. Epub 2011 May 31. 12.Liu Y, Mu C, Ying X, Li W, Wu N, Dong J, Gao Y, Shao N, Fan M, Yang G*. RNAIII activates map expression by forming an RNA–RNA complex in Staphylococcus aureus. FEBS Lett. 2011 Mar 23;585(6):899-905. Epub 2011 Feb 22. 13.Zhang X, Liu Y, Gao Y, Dong J, Mu C, Lu Q, Shao N, Yang G*. Inhibiting platelets aggregation could aggravate the acute infection caused by Staphylococcus aureus. Platelets. 2011; 22(3): 228-36. 14.Liu Y, Wu N, Dong J, Gao Y, Zhang X, Shao N, Yang G*. SsrA (tmRNA) acts as an antisense RNA to regulate Staphylococcus aureus pigment synthesis by base pairing with crtMN mRNA. FEBS Lett. 2010 Oct 22;584(20):4325-9. Epub 2010 Sep 19. 15.Liu Y, Wu N, Dong J, Gao Y, Zhang X, Mu C, Shao N, Yang G*. Hfq Is a Global Regulator That Controls the Pathogenicity of Staphylococcus aureus. PLoS One. 2010 Sep 29;5(9). pii: e13069. 16.Dong J, Gao Y, Liu Y, Shi J, Feng J, Li Z, Pan H, Xue Y, Liu C, Shen B, Shao N, Yang G*. The Protective Antibodies Induced by a Novel Epitope of Human TNF-a Could Suppress the Development of Collagen-Induced Arthritis. PLoS One. 2010 Jan 27;5(1):e8920. 17.Liu Z, Yang G (co-first author), Zhao T, Cao G , Xiong L, Xia W, Huang X, Wu, L Wu K, Fan M, Shao N, Zhu L. Small ncRNA Expression and Regulation Under Hypoxia in Neural Progenitor Cells. Cell Mol Neurobiol. 2011 Jan;31(1):1-5. Epub 2010 Oct 1. 18.Yang G, Gao YP , Feng JN, Huang Y, Li SH, Liu Y, Liu C, Fan M, Shen BF, Shao NS. C-terminus of TRAP in Staphylococcus can enhance the activity of lysozyme and lysostaphin. Acta Biochim Biophys Sin (Shanghai). 2008 May;40(5):452-8. 19.Sun Q, Zhang Y, Yang G(co-first author), Chen X, Zhang Y, Cao G, Wang J, Sun Y, Zhang P, Fan M, Shao N, Yang X. Transforming Growth Factor-β-Regulated miR-24 Promotes Skeletal Muscle Differentiation. Nucleic Acids Res. 2008 May;36(8):2690-9. Epub 2008 Mar 19. 20.Yang G, Gao Y, Dong J, Xue Y, Fan M, Shen B, Liu C, Shao N. A novel peptide isolated from phage library to substitute a complex system for a vaccine against staphylococci infection. Vaccine. 2006 Feb 20;24(8):1117-23..

学术兼职

世中联中医药免疫专业委员会常务理事，中国临床免疫学会委员，中国应用生物化学与分子生物学学会青年委员，中国医用生理学杂志编委