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研究领域

天然有机化学,有机合成和有机分析化学。主要包括:药用植物、传统中成药,微生物代谢物中活性部位和活性化合物的分离、结构分析和生物活性研究;生物活性化合物的衍生化反应和构效关系研究;药物合成。研究天然产物的分离方法,在不使用层析的情况下进行天然产物的制备分离。

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Li Xiangrong, Wei WanxingInternational Journal of Food Properties, and Lin Cuiwu ,Comparative analysis of essential oil compositions from Phyllanthus niriru, P. urinaria , and P. arenarius,Chemistry of Natural Compounds, 2008,44( 2),257-260. Wanxing Wei, Wu Zhou, et al,Structural analysis of a polysaccharide from Fructus Mori Albae,Carbohydrate Polymers,2007, 70(3), 341-344 Carboxylic acids from Phyllanthus urinaria Linn. Wanxing Wei, Yuanjian Pan, Yaozu Chen,et al. Chemistry of Natural Compounds,2005,41(1),17-21 阅览/下载 Two new compounds from Phyllanthus niruri , Wan-Xing Wei, Yuang-Jiang Pan, Hong Zhang, Cui-Wu lin, Teng -You Wei, Chemistry of Natural Compounds,2004, 5,460 - 464 An alkali-soluble heteroxylan from seeds of Phoenix dactylifera L., Omar Ishurd, Yousef Ali, Wanxing Wei, Yuanjiang Pan, Carbohydrate Research 2003, 338, 1609 阅览/下载 New Lignan Isolated from Phyllanthus niruri Linn. Structure Elucidation by NMR Spectroscopy.Wanxing Wei, Xingguo Gong, Omar Ishurd, Yuanjiang Pan. Bulletin of the Korea Chemical Society, 2002,23(6),896. 阅览/下载 Lignans with Activities of Anti-Hepatitis B Virus from Phyllanthus niruri Linn,Phytotherapy Research, 26: 964–968 (2012) Structure in Crystal and in solution of Friedelin Isolated from Phyllanthus niruri Linn,韦万兴, 潘远江,张虹,陈耀祖.天然产物研究与开发,2004,16(3),201. The Crystal Structure of One Nature Compound: 1,12- Diazacyclodocosane -2,11 - dione. Wanxing Wei, Yuanjiang Pan.Bulletin of the Korea Chemical Society, 2002,23(11),1552.http://journal.kcsnet.or.kr/kcs/bkcs/bkcs_index.htm 阅览/下载 Synthesis and antiproliferative activity of some steroidal lactone compounds, Steroids,2012,77,255–259 Synthesis and in vitro antiproliferative evaluation of some ring B abeo-sterols,Steroids ,2012,77, 1061–1068 Preparation of a genipin blue from egg protein and genipin, Natural Product Research ,2012, 8, 765-769 Isolation and X-ray crystal structure of a securinega-type alkaloid from Phyllanthus niruri Linn, Natural Product Research,2012, 8, 762-764 Glucomannans of Serissa serissoides Stem,Chemistry of Natural Compounds, 47(2),2011,176-178 Simply and Effectively Large-Scale Preparation of Geniposide from Fruit of Gardenia Jasminoides Ellis by Liquid-Liquid Two-Phase Extraction, Fitoterapia, 2012,83,1558–1561. In vitro and in vivo anti-hepatitis B virus activities of the lignan nirtetralin B isolated from Phyllanthus niruri L.Sheng Liu, Wanxing Wei*, Yubin Li, Xing Lin, Kaichuang Shi, Xun Cao, Min Zhou.Journal of Ethnopharmacology,2014,157(18) 62-68。 In vitro and in vivo anti-hepatitis B virus activities of the lignan niranthin isolated from Phyllanthus niruri L.1067Sheng Liu, Wanxing Wei*, Kaichuang Shi, Xun Cao, Min Zhou, Zhiping Liu. Journal of Ethnopharmacology, 2014,155(2), 1061- 1067. 刘盛,(*)韦万兴,李宇斌,刘旭,曹小吉,雷科婵,周敏,Design, synthesis, biological evaluation and molecular docking studies of phenylpropanoid derivatives as potent anti-hepatitis B virus agents,European Journal of Medicinal Chemistry,2015,95:473-482。 刘盛,李宇斌,韦万兴(*),王奎武,王立升,王坚毅,Design, Synthesis, Molecular Docking Studies and Anti-HBV Activity of Phenylpropanoid Derivatives,Chemico-Biological Interactions, 2016, 251,1-9 (SCI) 刘盛,李宇斌,韦万兴(*) ,韦京辰,Synthesis and biological evaluation of phenylpropanoid derivatives,Medicinal Chemistry Research(接受,日期2016/3/3,DOI: 10.1007/s00044-016-1554-6)(SCI)。 In Vitro Antioxidant Activity of the Anthocyanins in Sageretia theezans Brongn Fruit,雷科婵,韦万兴(*) ,刘盛,周敏,林小霞,曹洵,International Journal of Food Properties, 19(1), pp 210-221, 2016/3/15. 刘志平,韦万兴*,甘春芳,黄燕敏,刘盛,周敏,崔建国,柚皮苷半合成 E-柚皮素肟类化合物及细胞活性, 有机化学,2013, 33, 2551~2558。(SCI) 刘志平,韦万兴*,甘春芳,黄燕敏,刘盛,崔建,E-橙皮素肟类化合物的合成及对SGB-7901的细胞活性, 有机化学,2013, 33, 1970~1974。(SCI) 刘志平,韦万兴*,甘春芳,黄燕敏,刘盛,周敏,崔建国,N-亚苄基橙皮素腙及类似物的合成与细胞活性, 有机化学,2013, 33, 1988~1993。(SCI)

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