娄强 - 河南大学 - 基础医学院

个人简介

2010年博士毕业于复旦大学上海医学院教育部/卫生部医学分子病毒学重点实验室病原生物学专业；现在河南大学医学院微生物学教研室、抗体药物河南省工程实验室、河南省细胞与分子免疫学重点实验室工作。2014年-2016年在美国Medical College of Georgia大学做访问学者。

研究领域

主要从事细菌感染、肾脏损伤与保护方面的研究，目前研究方向为压力状态下（亚砷酸盐、顺铂、热休克等）细胞生存、凋亡的反应及对microRNAs的调控。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Lou Q, Hu Y, Ma Y, Dong Z: Heat shock factor 1 induces Crystallin-αB to protect against cisplatin nephrotoxicity.Am J Physiol Renal Physiol2016. 2. Lou Q, Ma Y, Qu D: Two-component signal transduction system SaeRS is involved in competence and penicillin susceptibility in Staphylococcus epidermidis.J Basic Microbiol2016, 56(4):358-368. 3. Lou Q, Zhang W, Liu G, Ma Y: The C-type lectin OCILRP2 costimulates EL4 T cell activation via the DAP12-Raf-MAP kinase pathway.PLoS One2014, 9(11):e113218. 4. Lou Q, Qi Y, Ma Y, Qu D:Two component signal transduction system SaeRS positively regulatesStaphylococcus epidermidisglucose metabolism.The Scientific World Journal2014:908121. 5. Lou Q, Zhu T, Hu J, Ben H, Yang J, Yu F, Liu J, Wu Y, Fischer A, Francois Pet al: Role of the SaeRS two-component regulatory system inStaphylococcus epidermidisautolysis and biofilm formation.BMC Microbiol2011, 11:146. 6. 娄强, 谢盼盼, 崔秀坤, 马远方, 胡延忠: 致白内障基因Hsf4bK65R位点突变对下游热休克蛋白表达的影响.中国病理生理杂志2015, 31(9):1699-1703. 7. 娄强, 王耀辉,瞿涤, 马远方: 双组分信号转导系统saeRS对表皮葡萄球菌生存能力的影响.四川大学学报(医学版)2015, 46(1):27-30. 8. 娄强, 张薇, 刘广超, 马远方: 联合应用CD3/CD28单克隆抗体对小鼠T淋巴瘤细胞EL4活化的影响.中国免疫学杂志2013, 29(6):580-583. 9. 娄强, 王艳歌, 瞿涤: 表皮葡萄球菌双组分信号转导系统saeRS对相关蛋白调控的研究.西安交通大学学报(医学版）2012, 33(6):680-684. 10. 娄强, 朱涛, 王家学, 吴旸, 朱玉莉, 瞿涤: 表皮葡萄球菌基因删除突变株构建方法的研究.微生物与感染2008, 3(1):11-15. 11. Cui X, Xie PP, Jia PP,Lou Q, Dun G, Li S, Liu G, Zhang J, Dong Z, Ma Y, Hu Y: Hsf4 counteracts Hsf1 transcription activities and increases lens epithelial cell survival in vitro.Biochim Biophys Acta2015, 1853(3):746-755. 12. Ma W, Zhang Y, Mu H, Qing X, Li S, Cui X,Lou Q, Ma Y, Pu H, Hu Y: Glucose regulates heat shock factor 1 transcription activity via mTOR pathway in HCC cell lines.Cell Biol Int2015, 39(11):1217-1224. 13. Li S, Ma W, Fei T,Lou Q, Zhang Y, Cui X, Qin X, Zhang J, Liu G, Dong Z, Ma Y, Song Z, Hu Y: Upregulation of heat shock factor 1 transcription activity is associated with hepatocellular carcinoma progression.Mol Med Rep2014, 10(5):2313-2321. 14. Qi YJ, Wang M, Liu RM, Wei H, Chao WX, Zhang T,Lou Q, Li XM, Ma J, Zhu H, Yang ZH, Liu HQ, Ma YF: Downregulation of 14-3-3σ correlates with multistage carcinogenesis and poor prognosis of esophageal squamous cell carcinoma.PLoS One2014, 9(4):e95386. 15. Zhang J, Ma Z, Wang J, Li S, Zhang Y, Wang Y, Wang M, Feng X, Liu X, Liu G,Lou Q, Cui X, Ma Y, Dong Z, Hu YZ: Regulation of Hsf4b nuclear translocation and transcription activity by phosphorylation at threonine 472.Biochim Biophys Acta2014, 1843(3):580-589. 16. Qi YJ, Ward DG, Pang C, Wang QM, Wei W, Ma J, Zhang J,Lou Q, Shimwell NJ, Martin Aet al:Proteomic Profiling of N-linked Glycoproteins Identifies ConA-binding Pro-cathepsin D as a Novel Serum Biomarker for Hepatocellular Carcinoma.Proteomics2014, 14(2-3):186-195. 17. 王耀辉,娄强, 陈九格, 张军, 马远方: 免疫调节因子TIPE2慢病毒载体的构建及病毒包装.中国免疫学杂志2013, 29(10):1077-1079. 18. Wu Y, Wang J, Xu T, Liu J, Yu W,Lou Q, Zhu T, He N, Ben H, Hu Jet al: The Two-Component Signal Transduction System ArlRS Regulates Staphylococcus epidermidis Biofilm Formation in an ica-Dependent Manner.PLoS One2012, 7(7):e40041. 19. 王艳鸽,娄强, 董烁: Huntington舞蹈病一家系4例遗传分析.河南大学学报（医学版）2012, 31(1):39-44. 20. Hu J, Xu T, Zhu T,Lou Q, Wang X, Wu Y, Huang R, Liu J, Liu H, Yu Fet al: Monoclonal antibodies against accumulation-associated protein affect EPS biosynthesis and enhance bacterial accumulation ofStaphylococcus epidermidis.PLoS One2011, 6(6):e20918.

学术兼职

中国免疫学会成员、中国细胞生物学会成员等