个人简介
学历背景
2011.9-2016.6 苏州大学，博士
2007.9-2011.6 安庆师范大学，本科
工作经历
2016.9-至今 河南大学，生命科学学院，讲师
研究领域
仿生纳米药物的构建、化药/基因药物的精准递送、脑相关疾病的靶向治疗、CRSPR基因编辑载体的设计
近期论文
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1. Yan Zou, Yaohua Wei, Yinping Sun, Jie Bao, Feirong Yao, Zekai Li, Fenghua Meng*, Chunhong Hu, Gert Storm and Zhiyuan Zhong*, Cyclic RGD-functionalized and disulfide-crosslinked iodine-rich polymersomes as a robust and smart theranostic agent for targeted CT imaging and chemotherapy of tumor. Theranostic. 2019, 9 (26), 8061-8072.
2. Yan Zou, Yanjie Liu, Zhipeng Yang, Dongya Zhang, Yiqing Lu, Meng Zheng*, Xue Xue, Jia Geng, Roger Chung, and Bingyang Shi*, Effective and targeted human orthotopic glioblastoma xenograft therapy via a multifunctional biomimetic nanomedicine, Advanced Materials, 2018, 201803717
3. Yan Zou, Jingjing Wei, Yifeng Xia, Fenghua Meng*, Jiandong Yuan, Zhiyuan Zhong*, Targeted chemotherapy for subcutaneous and orthotopic non-small cell lung tumors with cyclic RGD-functionalized and disulfide-crosslinked polymersomal doxorubicin, Signal Transduction and Targeted Therapy, 2018, 3 (32), DOI: 10.1038/s41392-018-0032-7
4. Yan Zou, Yifeng Xia, Fenghua Meng*, Jian Zhang, Zhiyuan Zhong*, GE11-directed functional polymersomal doxorubicin as an advanced alternative to clinical liposomal formulation for ovarian cancer treatment, Molecular Pharmaceutics, 2018, 15 (9), 3664–3671
5. Yan Zou, Meng Zheng, Weijing Yang, Fenghua Meng*, Kanjiro Miyata, Hyun Jin Kim, Kazunori Kataoka*, Zhiyuan Zhong*, Virus-mimicking chimaeric polymersome boosts targeted cancer siRNA therapy in vivo, Advanced Materials, 2017, 201703285
6. Yan Zou, Yaohua Wei, Guanglin Wang, Fenghua Meng*, Mingyuan Gao, Gert Storm and Zhiyuan Zhong*. Nano-polymersomes with a ultrahigh iodine content for high-performance X-Ray computed tomography imaging in vivo. Advanced Materials, 2017, 201603997.
7. Yan Zou, Fenghua Meng*, Jian Zhang, Zhiyuan Zhong*, Highly efficacious and targeted chemotherapy of human lung cancer by α3β1 integrin specific, redox-responsive and reversibly crosslinked polymersomes, Journal of Controlled Release, 2017, 259: e65
8. Wei Chen, Yan Zou (co-first author), Zhiyuan Zhong*, Raigner Haag*, Cyclo(RGD)-decorated reduction-responsive nanogels mediate targeted chemotherapy of integrin overexpressing human glioblastoma in vivo, Small, 2017, 13 (6), 201601997
9. Chufeng Hang, Yan Zou (co-first author), Yinan Zhong, Zhiyuan Zhong*, Fenghua Meng*, NIR and UV-responsive degradable hyaluronic acid nanogels for CD44-targeted and remotely triggered intracellular doxorubicin delivery, Colloids and Surfaces B: Biointerfaces, 2017, 158, 547- 555
10. Yan Zou, Ya Fang, Hao Meng, Fenghua Meng*, Chao Deng, Jian Zhang, and Zhiyuan Zhong*. Self-crosslinkable and intracellularly decrosslinkable biodegradable micellar nanoparticles: A robust, simple and multifunctional nanoplatform for high-efficiency targeted cancer chemotherap. Journal of Controlled Release 2016, 244, 326-335.
11. Yan Zou, Fenghua Meng*, Chao Deng, and Zhiyuan Zhong*. Robust, tumor-homing and redox-sensitive polymersomal doxorubicin: A superior alternative to Doxil and Caelyx? Journal of Controlled Release 2016, 239, 149-158.
12. Yan Zou, Yuan Song, Weijing Yang, Fenghua Meng*, Haiyan Liu and Zhiyuan Zhong*, Galactose-installed photo-crosslinked pH-Sensitive degradable micelles for active targeting chemotherapy of hepatocellular carcinoma in mice. Journal of Controlled Release 2014, 193, 154-161.
13. Yan Zou, Fenghua Meng*, Weijing Yang, and Zhiyuan Zhong*, Targeted hepatoma chemotherapy in vivo using galactose-decorated crosslinked pH-sensitive degradable micelles. Journal of Controlled Release 2015, 213, e125-e126.
学术兼职
特刊客座编辑：Journal of Nanomaterials
审稿编辑：Frontier in Chemistry
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