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个人简介

Education B.S. (NJU, China) 2002 Ph.D. (CIAC, CAS, China), 2009 Career Professor, Southeast Univ., China 2012- ICYS Researcher, NIMS, 2009-2012 Postdoctoral Fellow, MPI-KG, Germany 2008-2009 张袁健(PI),东南大学首席教授、二级教授,博士生导师、化学化工学院副院长,入选国家青年海外高层次人才计划和国家万人计划科技创新领军人才,英国皇家化学会会士(Fellow of the Royal Society of Chemistry)。1998年-2007年先后在南京大学(NJU)基础学科教学强化部和中国科学院长春应用化学研究所(CIAC, CAS)学习获学士和博士学位,2008年-2012年先后在德国马普胶体界面研究所(MPI-KG)和日本国立物质材料研究所(NIMS)国际青年科学家中心(ICYS)从事科研任博士后和ICYS Researcher(Tenure-Track),2012年起受聘于东南大学(SEU)化学化工学院。长期从事碳基分子传感的研究(Carbosensing,“碳”测), 已在J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Chem、Nat. Commun.、CCS Chem.、Anal. Chem.等发表论文100余篇。研究成果受到国际国内同行的广泛关注,所发表论文被引用18,000余次,研究论文单篇最高被引用1200余次,H-index 67。作为项目负责人承担国家自然科学基金委、江苏省科技厅、日本学术振兴会等相关科研项目,兼任江苏省材料学会常务理事、江苏省化学化工学会理事、Chinese Chemical Letters (中国化学快报) 副主编等。

研究领域

We are interested but not limited to Carbosensing: Carbon Matter-Derived Optoelectronic Sensors, and have expertise in electroanalytical and optoelectronic biosensors, materials chemistry (especially that of conjugated carbonaceous materials), and electrochemiluminescence, electrocatalysis, photocatalysis and photoelectrochemistry for signal transducing and energy conversion.

近期论文

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Sijia Zhou‡, Tianyi Zhou‡, Yuhua Hou‡, Wang Li, Yanfei Shen, Songqin Liu, Kaiqing Wu*, Yuanjian Zhang*, “Recent advances in electrochemiluminescence based on polymeric luminophores“, Chin. Chem. Lett. 2024, 110284. Nina Lin, Yu Ouyang, Yunlong Qin, Ola Karmi, Yang Sung Sohn, Songqin Liu, Rachel Nechushtai, Yuanjian Zhang*, Itamar Willner*, and Zhixin Zhou*, “Spatially Localized Entropy-Driven Evolution of Nucleic Acid-Based Constitutional Dynamic Networks for Intracellular Imaging and Spatiotemporal Programmable Gene Therapy”, J. Am. Chem. Soc. 2024, DOI: 10.1021/jacs.4c03651. Kaiyuan Wang, Qing Hong, Cai Zhu,Yuan Xu, Wang Li, Wenhao Chen, Xiang Gu, Xinghua Chen, Yanfeng Fang, Yanfei Shen*, Songqin Liu, and Yuanjian Zhang*, “Metal-ligand dual-site SAzyme with uricase-like mechanism for specific uric acid oxidation”, Nat. Commun. 2024, 15, 5705. ChemRxiv, 18 December 2023. Jin Ma‡, Cheng Peng‡, Xiaoxiao Peng, Sicheng Liang, Zhixin Zhou, Kaiqing Wu, Ran Chen, Songqin Liu, Yanfei Shen*, Haibo Ma*, and Yuanjian Zhang*, “H2O2 Photosynthesis from H2O and O2 under Weak Light by Carbon Nitrides with Piezoelectric Effect”, J. Am. Chem. Soc. 2024, accepted. ChemRxiv, 27 December 2023. Ying Wang‡, Hong Yang‡, Caixia Zhu‡, Qing Hong, Xuwen Cao, Kaiyuan Wang, Yuan Xu, Yanfei Shen*, Songqin Liu, and Yuanjian Zhang*, “Cascading oxidoreductases-like nanozymes for high selective and sensitive fluorescent detection of ascorbic acid”, Chin. Chem. Lett. 2024, 110153. Based on the oxidase-like N-doped carbon nanocages (NC) and peroxidase-like copper oxide (CuO), a cascade fluorescent biosensor for ascorbic acid was reported with high selectivity and sensitivity. Yuan Xu, Yuanjie Ma, Xinghua Chen, Kaiqing Wu, Kaiyuan Wang, Yanfei Shen, Songqin Liu, Xuejiao Gao*, and Yuanjian Zhang*, “Regulating Reactive Oxygen Intermediates of Fe–N–C SAzyme via Second-Shell Coordination for Selective Aerobic Oxidation Reactions”, Angew. Chem. Int. Ed. 2024, e202408935. Yanfeng Fang‡, Hong Yang‡, Yuhua Hou, Wang Li, Yanfei Shen*, Songqin Liu, and Yuanjian Zhang*, “Timescale correlation of shallow trap states increases electrochemiluminescence efficiency in carbon nitrides”, Nat. Commun. 2024, 15, 3597. Linru Guo‡, Yida Han‡, Hong Yang‡, Jie Fu, Wang Li, Ran Xie*, Yuanjian Zhang*, Kang Wang*, and Xing-Hua Xia, “Single-Molecule Discrimination of Saccharides Using Carbon Nitride Nanopores”, Nano Lett. 2024, DOI: 10.1021/acs.nanolett.4c01223. Caixia Zhu, Qing Hong, Kaiyuan Wang, Yanfei Shen*, Songqin Liu, and Yuanjian Zhang*, “Single nanozyme-based colorimetric biosensor for dopamine with enhanced selectivity via reactivity of oxidation intermediates”, Chin. Chem. Lett. 2024, DOI:10.1016/j.cclet.2024.109560. Caixia Zhu, Hong Yang, Xuwen Cao, Qing Hong, Yuan Xu, Kaiyuan Wang, Yanfei Shen*, Songqin Liu, and Yuanjian Zhang*, “Decoupling of the Confused Complex in Oxidation of 3,3′,5,5′-Tetramethylbenzidine for the Reliable Chromogenic Bioassay”, Anal. Chem. 2023, DOI: 10.1021/acs.analchem.3c03998. Wang Li‡, Mingming Zhang‡, Dan Han, Hong Yang, Qing Hong, Yanfeng Fang, Zhixin Zhou, Yanfei Shen, Songqin Liu, Chaofeng Huang*, Haibin Zhu*, and Yuanjian Zhang*, “Carbon Nitride-Based Heterojunction Photoelectrodes with Modulable Charge-Transfer Pathways toward Selective Biosensing”, Anal. Chem. 2023, 95, 13716–13724. Caixia Zhu, Zhixin Zhou, Xuejiao Gao, Yanhong Tao, Xuwen Cao, Yuan Xu, Yanfei Shen, Songqin Liu, and Yuanjian Zhang*, “Cascade Nanozymatic Network Mimicking Cells with Selective and Linear Perception of H2O2”, Chem. Sci. 2023, DOI: 10.1039/D3SC01714A. Zhixin Zhou*‡, Nina Lin‡, Yu Ouyang, Songqin Liu, Yuanjian Zhang*, and Itamar Willner*, “Cascaded, Feedback-Driven, and Spatially Localized Emergence of Constitutional Dynamic Networks Driven by Enzyme-Free Catalytic DNA Circuits”, J. Am. Chem. Soc. 2023, DOI: 10.1021/jacs.3c02083. Qing Hong‡, Hong Yang‡, Yanfeng Fang, Wang Li, Caixia Zhu, Zhuang Wang, Sicheng Liang, Xuwen Cao, Zhixin Zhou, Yanfei Shen*, Songqin Liu & Yuanjian Zhang*, “Adaptable graphitic C6N6-based copper single-atom catalyst for intelligent biosensing”, Nat. Commun. 2023, 14, 2780. Xuwen Cao‡, Caixia Zhu‡, Qing Hong, Xinghua Chen, Kaiyuan Wang, Yanfei Shen*, Songqin Liu, and Yuanjian Zhang*, “Insights into Iron Leaching from an Ascorbate-Oxidase-like Fe–N–C Nanozyme and Oxygen Reduction Selectivity”, Angew. Chem. Int. Ed. 2023, e202302463 Yanfeng Fang, Zhixin Zhou*, Yuhua Hou, Chenchen Wang, Xuwen Cao, Songqin Liu, Yanfei Shen*, and Yuanjian Zhang*, “Highly Efficient Wavelength-Resolved Electrochemiluminescence of Carbon Nitride Films for Ultrasensitive Multiplex MicroRNA Detection”, Anal. Chem. 2023, DOI: 10.1021/acs.analchem.2c05740 Xiaoxiao Peng,‡ Jin Ma,‡ Zhixin Zhou, Hong Yang, Jingjing Chen, Ran Chen, Kaiqing Wu, Guangcheng Xi, Songqin Liu, Yanfei Shen* and Yuanjian Zhang*, “Molecular Assembly of Carbon Nitride-Based Composite Membrane for Photocatalytic Sterilization and Wound Healing”, Chem. Sci. 2023, 14, 4319-4327 Kaiqing Wu, Ran Chen, Zhixin Zhou, Xinghua Chen, Yanqin Lv, Jin Ma, Yanfei Shen, Songqin Liu, and Yuanjian Zhang*, “Elucidating Electrocatalytic Oxygen Reduction Kinetics via Intermediates by Time-Dependent Electrochemiluminescence”, Angew. Chem. Int. Ed. 2023, 62, e202217078 Yuhua Hou‡, Yanfeng Fang‡, Zhixin Zhou, Qing Hong, Wang Li, Hong Yang, Kaiqing Wu, Yuan Xu, Xuwen Cao, Dan Han, Songqin Liu, Yanfei Shen, and Yuanjian Zhang*, “Growth of Robust Carbon Nitride Films by Double Crystallization with Exceptionally Boosted Electrochemiluminescence for Visual DNA Detection”, Adv. Optical Mater. 2023, 11, 2202737 Kaiqing Wu, Jingjing Ji, Hong Yang, Zhixin Zhou, Ran Chen, Sicheng Liang, Wang Li, Yanfei Shen, Songqin Liu, and Yuanjian Zhang*, “Multifunctional semiconducting carbon nitrides enabling sequential fluorescent sensing of telomerase activity and internal self-checking”, Sensors and Actuators B: Chemical 2023, 378, 133170 Ran Chen, Xin Wang, Kaiqing Wu, Songqin Liu, and Yuanjian Zhang*, “Voltammetric Study and Modeling of the Electrochemical Oxidation Process and the Adsorption Effects of Luminol and Luminol Derivatives on Glassy Carbon Electrodes”, Anal. Chem. 2022, 94, 17625-17633 Jin Ma, Xiaoxiao Peng, Zhixin Zhou, Hong Yang, Kaiqing Wu, Zhengzou Fang, Dan Han, Yanfeng Fang, Songqin Liu, Yanfei Shen, and Yuanjian Zhang*, “Extended Conjugation Refining Carbon Nitride for Non-sacrificial H2O2 Photosynthesis and Hypoxic Tumor Therapy”, Angew. Chem. Int. Ed. 2022, 61, e202210856 Dan Han, Hong Yang, Zhixin Zhou, Kaiqing Wu, Jin Ma, Yanfeng Fang, Qing Hong, Guangcheng Xi, Songqin Liu, Yanfei Shen, and Yuanjian Zhang*, “Photoelectron Storages in Functionalized Carbon Nitrides for Colorimetric Sensing of Oxygen”, ACS Sensors 2022, 7, 2328–2337. Yanfeng Fang, Yuhua Hou, Hong Yang, Ran Chen, Wang Li, Jin Ma, Dan Han, Xuwen Cao, Songqin Liu, Yanfei Shen, and Yuanjian Zhang*, “Elucidating Orbital Delocalization Effects on Boosting Electrochemiluminescence Efficiency of Carbon Nitrides”, Adv. Optical Mater. 2022, 10, 2201017. Orbital delocalization, associated with the evolution of the complicated molecule during the thermal condensation of carbon nitrides, is disclosed as a unified and quantifiable intrinsic factor for their electrochemiluminescence (ECL) efficiency. Moreover, a general approach for evaluating ECL kinetics was established, which excluded the inevitable dependency between ECL efficiency and photoluminescent quantum yield of luminophores. Yongjun Zheng, Hong Yang, Lufang Zhao, Yuhan Bai, Xinghua Chen, Kaiqing Wu, Songqin Liu, Yanfei Shen, and Yuanjian Zhang*, “Lighting Up Electrochemiluminescence-Inactive Dyes via Grafting Enabled by Intramolecular Resonance Energy Transfer”, Anal. Chem. 2022, 94, 3296–3302. Most dyes with excellent photophysical properties are electrochemiluminescence (ECL)-inactive in aqueous solutions. A general way to light up ECL inactive dyes was reported by grafting, a well-developed concept for plant propagation since 500 BCE. It opens a promising way to address the scarcity of ECL emitters and bring unprecedented functions. Qing Zhou, Hong Yang, Xinghua Chen, Yuan Xu, Dan Han, Sisi Zhou, Songqin Liu, Yanfei Shen, and Yuanjian Zhang*, “Cascaded Nanozyme system with High Reaction Selectivity by Substrate Screening and Channeling in a Microfluidic Device”, Angew. Chem. Int. Ed. 2022, 61, e202112453. Xinghua Chen, Caixia Zhu, Yuan Xu, Kaiyuan Wang, Xuwen Cao, Yanfei Shen, Songqin Liu and Yuanjian Zhang*, “Quantitative Evaluation of O2 Activation Half-Reaction for Fe-N-C in Oxidase-Like Activity Enhancement”, Catal. Sci. Technol. 2021, DOI: 10.1039/D1CY01537K. Hong Yang, Qing Zhou, Zhengzou Fang, Wang Li, Yongjun Zheng, Jin Ma, Zhuang Wang, Lufang Zhao, Songqin Liu, Yanfei Shen, and Yuanjian Zhang*, “Carbon Nitride of Five-Membered Rings with Low Optical Bandgap for Photoelectrochemical Biosensing”, Chem 2021, 7, 2708–2721. Yuhan Bai‡, Yongjun Zheng‡, Zhuang Wang, Qing Hong, Songqin Liu, Yanfei Shen, and Yuanjian Zhang*, “ Metal-Doped Carbon Nitrides: Synthesis, Structure and Applications”, New J. Chem. 2021, 45, 11876-11892. Xinghua Chen, Lufang Zhao, Kaiqing Wu, Hong Yang, Qing Zhou, Yuan Xu, Yongjun Zheng, Yanfei Shen, Songqin Liu, and Yuanjian Zhang*, “Bound Oxygen-Atom Transfer Endowing Peroxidase-Mimic M-N-C with High Substrate Selectivity”, Chem. Sci. 2021, 12, 8865-8871. Chaofeng Huang‡, Yaping Wen‡, Jin Ma‡, Dandan Dong, Yanfei Shen, Songqin Liu, Haibo Ma* and Yuanjian Zhang*, “Unraveling Fundamental Active Units in Carbon Nitride for Photocatalytic Oxidation Reactions”, Nat. Commun. 2021, 12, 320. Yuye Zhang†, Yongxiu Song†, Yanfei Shen, Kaiyang Chen, Qing Zhou, Yanqin Lv, Hong Yang, Ensheng Xu, Songqin Liu, Lei Liu* and Yuanjian Zhang*, “Water Molecules-Triggered Anisotropic Deformation of Carbon Nitride Nanoribbons Enabling Contactless Respiratory Inspection”, CCS Chemistry 2021, 3, 1615–1625. Yuan Xu, Jing Xue, Qing Zhou, Yongjun Zheng, Xinghua Chen, Songqin Liu, Yanfei Shen, and Yuanjian Zhang*, “The Fe-N-C Nanozyme with Both Accelerated and Inhibited Biocatalytic Activities Capable of Accessing Drug-Drug Interaction”, Angew. Chem. Int. Ed. 2020, 59, 14498-14503 (Hot Paper). Jianhai Wang, Yanfei Shen, Songqin Liu, and Yuanjian Zhang*, “Single 2D MXene Precursor-Derived TiO2 Nanosheets with a Uniform Decoration of Amorphous Carbon for Enhancing Photocatalytic Water Splitting”, Appl. Cat. B: Environ. 2020, 118885. Qing Zhou‡, Guanghui Li‡, Kaiyang Chen, Hong Yang, Mengran Yang, Yuye Zhang, Yakun Wan*, Yanfei Shen*, and Yuanjian Zhang*, “Simultaneous Unlocking Optoelectronic and Interfacial Properties of C60 for Ultrasensitive Immunosensing by Coupling to Metal−Organic Framework”, Anal. Chem. 2020, 92, 983-990. Tingting Zhao, Qing Zhou, Yanqin Lv, Dan Han, Kaiqing Wu, Lufang Zhao, Yanfei Shen, Songqin Liu, and Yuanjian Zhang*, “Ultrafast Condensation of Carbon Nitride on Electrodes with Exceptional Boosted Both Photocurrent and Electrochemiluminescence”, Angew. Chem. Int. Ed. 2020, 59, 1139-1143. Ziyu Gan, Chao feng Huang, Yanfei Shen, Qing Zhou, Dan Han, Jin Ma, Songqin Liu, and Yuanjian Zhang*, “Preparation of carbon nitride nanoparticles by nanoprecipitation method with high yield and enhanced photocatalytic activity”, Chinese Chem. Lett. (中国化学快报) 2020, 31, 513-516 Dongya Ni, Yuye Zhang*, Yanfei Shen, Songqin Liu, and Yuanjian Zhang*, “Promoting condensation kinetics of polymeric carbon nitride for enhanced photocatalytic activities”, Chinese Chem. Lett. (中国化学快报) 2020, 31, 115-118. Lufang Zhao, Jingjing Ji, Yanfei Shen, Kaiqing Wu, Tingting Zhao, Hong Yang, Yanqin Lv, Songqin Liu, and Yuanjian Zhang*, “Exfoliation and Sensitization of 2D Carbon Nitride for Photoelectrochemical Biosensing under Red Light”, Chem. Eur. J. 2019, 25, 15680– 15686 Dan Han, Dongya Ni, Qing Zhou, Jingjing Ji, Yanqin Lv, Yanfei Shen, Songqin Liu, and Yuanjian Zhang*, “Harnessing Photoluminescent Properties of Carbon Nitride Nanosheets in a Hierarchical Matrix”, Adv. Funct. Mater. 2019, 1905576. Jianhai Wang, Qing Zhou, Yanfei Shen, Xinghua Chen, Songqin Liu, and Yuanjian Zhang*, “Carbon Nitride Co-Catalyst Activation Using N-doped Carbon with Enhanced Photocatalytic H2 Evolution”, Langmuir 2019, 35, 12366-12373 Jingjing Ji, Lufang Zhao, Yanfei Shen, Songqin Liu, and Yuanjian Zhang*, “Covalent stabilization and functionalization of MXene via silylation reactions with improved surface properties”, FlatChem. 2019, 17, 100128 Mengran Yang, Hao Mei, Yanfei Shen, Kaiqing Wu, Deng Pan, Songqin Liu, Ting Zhang, and Yuanjian Zhang*, “Hot‐Tailoring of Carbon Nitride Dots with Red‐Shifted Photoluminescence for Visual Double Text Encrypt and Bioimaging”, Chem. Eur. J. 2019, 25, 10188-10196 Hao Mei, Mengran Yang, Yanfei Shen, Fei He, Zhixin Zhou, Xinghua Chen, Yiran Yang, Songqin Liu, and Yuanjian Zhang*,”Non-Covalent Pre-Organization of Molecular Precursors: A facile Approach for Engineering Structures and Activities of Pyrolyzed Co-N-C Electrocatalysts”, Carbon 2019, 144, 312-320. Li Shangguan, Yuanqing Wei, Kan Wang, Yuanjian Zhang*, and Songqin Liu*,”Highly sensitive fluorescent bioassay of 2,3,7,8-tetrachloro-dibenzo-p-dioxin based on abnormal expression of cytochrome P450 1A2 in human cells”, Anal. Chim. Acta 2019, 1046, 179-184

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