个人简介
2010年12月，毕业于山东大学微生物技术国家重点实验室生物化学与分子生物学专业，获博士学位，2011年被引进至河北大学工作。
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Xiuhua Liu, Qian Du, ZhiWang, Deyu Zhu, Yan Huang, Ning Li, TiandiWei, Sujuan Xu, Lichuan Gu*. Crystal structure and biochemical features of EfeB/YcdB from Escherichia coli O157: Asp235 plays divergent roles in different enzyme-catalyzed processes. J. Biol. Chem, 2011, 286: 14922-14931. (SCI, IF: 5.38)
Guijun Shang, Xiuhua Liu, Defen Lu, Junbing Zhang, Ning Li, Chunyuan Zhu, Shiheng Liu, Qian Yu, Yanyu Zhao, Heqiao Zhang, Junqiang Hu, Huaixing Cang, Sujuan Xu, Lichuan Gu*. Structural insight into how Pseudomonas aeruginosa peptidoglycanhydrolase Tse1 and its immunity protein Tsi1 function. Biochem J, 2012, 448(2): 201-11. (并列第一作者) (SCI, IF: 5.016)
Xiuhua Liu, Qian Du, Zhi Wang, Shiheng Liu, Ning Li, Ying Chen, Chunyuan Zhu, Deyu Zhu, Tiandi Wei, Yan Huang, Sujuan Xu, Lichuan Gu*. Crystal Structure of Periplasmic Catecholate-Siderophore Binding Protein VctP from Vibrio cholerae at 1.7 ? Resolution. FEBS Letters, 2012, 586 (8): 1240-1244. (SCI, IF: 3.54)
Xiuhua Liu, Jing Gong, Tiandi Wei, Zhi Wang, Qian Du, Deyu Zhu, Yan Huang, Sujuan Xu and Lichuan Gu*. Crystal structure of HutZ, a heme storage protein from Vibrio cholerae: A structural mismatch observed in the region of high sequence conservation. BMC Structural Biology, 2012, 12:23. (SCI, IF: 2.86)
Xiuhua Liu, Zhi Wang, Deyu Zhu, Tiandi Wei, Lichuan Gu, Sujuan Xu. Crystallization and preliminary X-ray crystallographic studies of VibE, a vibriobactin-specific 2, 3-dihydroxybenzoate-AMP ligase from Vibrio cholerae. Acta Cryst. F. 2011, 67: 1563-1565 (SCI, IF: 0.56).
Shiheng Liu, Conggang Zhang, Ning Li, Bei Niu, Mengyuan Liu, Xiuhua Liu, Tiandi Wei, Deyu Zhu, Yan Huang, Sujuan Xu and Lichuan Gu*. Structural insight into the ISC domain of VibB from Vibrio cholerae at atomic resolution: a snapshot just before the enzymatic reaction. Acta Cryst. D, 2012, 68, 1329-1338. (SCI, IF: 12.619)
Bingqing Li, Ning Li, Feng Wang, Liming Guo, Yan Huang, Xiuhua Liu, Tiandi Wei, Deyu Zhu, Cuilan Liu, Hongfang Pan, Sujuan Xu, Hong-Wei Wang and Lichuan Gu*. Structural insight of a concentration-dependent mechanism by which YdiV inhibits Escherichia coli flagellum biogenesis and motility. Nucleic Acids Res, 2012, 40(21): 11073-85. (SCI, IF: 8.02)
Ning Li, Conggang Zhang, Bingqing Li, Xiuhua Liu, Yan Huang, Sujuan Xu, and Lichuan Gu. An unique iron coordination in the iron-chelating molecule vibriobactin helps Vibrio cholera evade the mammalian siderocalin-mediated immune response. J. Biol. Chem. 2012, 287(12): 8912-8919 (SCI, IF: 5.38).
刘秀华, 刘建凤, 卢雪梅. 纤维弧菌的低温纤维素酶研究, 安徽农业科学, 2012, 40(3): 1281-1282.
刘秀华, 王执, 徐素娟. 霍乱弧菌中弧菌素合成酶VibF的A结构域基因的克隆.表达与纯化研究.河南农业科学. 2012, 41 (3): 149-153.
Jiaxu Wang, Zenglin Yuan, Yaqi Cui, Rong Xie, Guang Yang, Muzaffer A. Kassab, Mengxi Wang, Yinliang Ma, Chen Wu, Xiaochun Yu* and Xiuhua Liu*. Molecular basis for the inhibition of the methyl-lysine binding function of 53BP1 by TIRR, Nature Communications, 2018, 9: 2689.
Mengxi Wang, Zenglin Yuan, Rong Xie, Yinliang Ma, Xiuhua Liu* and Xiaochun Yu*. Structure-function analyses reveal the mechanism of the ARH3-dependent hydrolysis of ADP-ribosylation, Journal of Biological Chemistry, 2018，293(37): 14470–14480.
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