应优敏 - 浙江工业大学

研究领域

1）“基因——化学——活性”导向的天然来源（植物、微生物）来源药物先导化合物的发现与优化 2）基于内生真菌生物转化作用的宿主植物化学成分结构多样性研究

近期论文

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Ying YM, Li CY, Chen Y, Xiang JG, Fang L, Yao JB, Wang FS, Wang RW, Shan WG, Zhan ZJ. Lupane- and Friedelane-Type Triterpenoids from Celastrus stylosus. Chem. Biodivers., 2015, 12, 1222-1228. (2区TOP) Ying YM, Shan WG, Zhan ZJ. Biotransformation of Huperzine A by a Fungal Endophyte of Huperzia serrata Furnished Sesquiterpenoid − Alkaloid Hybrids. J. Nat. Prod., 2014, 77, 2054-2059. (1区TOP, IF 3.947) Ying YM, Zhang LY, Zhang X, Bai HB, Liang DE, Shan WG, Zhan ZJ. Terpenoids with Alpha-glucosidase Inhibitory Activity from the Submerged Culture of Inonotus obliquus. Phytochemistry, 2014, 108, 171-176. (1区TOP, IF 3.350) Ying YM, Shan WG, Zhang LW, Zhan ZJ. Ceriponols A-K, Tremulane Sesquitepenes from Ceriporia lacerate HS-ZJUT-C13A, a Fungal Endophyte of Huperzia serrata.Phytochemistry, 2013, 95, 360-367. (1区TOP, IF 3.350) Ying YM, Liu XS, Tong CP, Wang JW, Zhan ZJ, Shan WG. Lycopodium Alkaloids from Huperzia serrata. Helv. Chim. Acta, 2014, 97, 1433-1439. Ying YM, Zheng ZZ, Zhang LW, Shan WG, Wang JW, Zhan ZJ. Rare C25 steroids produced by Penicillium chrysogenum P1X, a fungal endophyte of Huperzia serrata. Helv. Chim. Acta,2014, 97, 95-101. Ying YM, Tong CP, Wang JW, Shan WG, Zhan ZJ. Ceriponol P, the first example of monocyclic tremulane sesquiterpene produced by Ceriporia lacerate a fungal endophyte of Huperzia serrata. J. Chem. Res., 2014, 38, 304-305. Ying YM, Zhang LW, Shan WG, Zhan ZJ. Secondary Metabolites of Peyronellaea sp. XW-12, an Endophytic Fungus of Huperzia serrata. Chem. Nat. Compd., 2014, 50, 723-725. Ying YM, Shan WG, Zhang LW, Chen Y, Zhan ZJ. Lanostane Triterpenes from Ceriporia lacerate HS-ZJUT-C13A, a Fungal Endophyte of Huperzia serrata. Helv. Chim. Acta, 2013, 96, 2092-2097. Ying YM, Shan WG, Liu WH, Zhan ZJ. Alkaloids and Nucleoside Derivatives from a Fungal Endophyte of Huperzia serrata. Chem. Nat. Compd., 2013, 49, 184-186. Ying YM, Zhan ZJ, Ding ZS, Shan WG. Bioactive metabolites from Penicillium sp. P-1, a fungal endophyte in Huperzia serrata. Chem. Nat. Compd., 2011, 47, 541-544. Ying YM, Shan WG, Liu WH, Zhan ZJ. Studies on the Metabolites of a Fungal Endophyte Penicillium sp. HS-5 from Huperzia serrata. Asian J. Chem.,2013, 25, 1208-1210. Zhan ZJ, Ying YM, Ma LF, Shan WG. Natural disesquiterpenoids. Nat. Prod. Rep., 28, 594-629, 2011.（IF: 10.715） Shan WG, Ying YM, Yu HN, Liu WH, Zhan ZJ. Helv Chim Acta, Diketopiperazine Alkaloids from Penicillium spp. HS-3, an Endophytic Fungus in Huperzia serrata. Helv. Chim. Acta, 2010, 93, 772-776. Zhan ZJ, Ying YM, Zhang FY, Li CP, Shan WG. Three New Illudalane Sequiterpenoids from Pteris semipinnata. Helv. Chim. Acta, 2010, 93, 550-554. Zhan ZJ, Jin JP, Ying YM, Shan WG. Furanone Derivatives from Aspergillus sp. XW-12, an Endophytic Fungus in Huperzia serrata. Helv. Chim. Acta, 2011, 94, 1454-1458. Shan WG, Chen XX, Ying YM, Zhan ZJ. Sesquiterpenoids from Fusarium sp., an Endophytic Fungus in Agriminia pilosa. Helv. Chim. Acta, 2011, 94, 1254-1259. Xiang JG, Shan WG, Liang DE, Ying YM, Gan LS, Wang JW, Zhan ZJ. N-Bearing Furanone Derivatives from an Endophytic Fungus in Huperzia serrata. Helv. Chim. Acta, 2013, 96, 997-1003.