张英霞 - 海南大学 - 生命科学与药学院

个人简介

张英霞，吉林省集安市人。2005年毕业于中国科学院昆明动物研究所，获动物学博士学位。海南大学生命科学与药学院药学系，教授，博士生导师。曾于日本京都大学，美国密苏里州立大学，美国内布拉斯加大学医学院访学。海南省“515”人才工程第二层次人选。

研究领域

海洋生物及两栖动物来源的生物活性蛋白与多肽。目前主要研究海洋生物及海南两栖动物来源的天然抗菌肽抗菌，抗氧化，抗肿瘤等生物活性及机制，并以天然抗菌肽为模板，对其进行筛选优化与功能设计，以获得生物学活性优良的新型结构与功能的抗菌肽，开发拥有自主知识产权的抗菌肽候选药物

近期论文

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Mishra B, Wang XQ, Lushnikova T, Zhang YX, Golla RM, Narayana JL, Wang CF, McGuiree TR, Wang GS, Antibacterial, antifungal, anticancer activities and structural bioinformatics analysis of six naturally occurring temporins, Peptides, 2018, 106: 9–20. Dong Z, Luo WJ, Zhong HR, Wang MCRG, Song YT, Deng SM, Zhang YX*. Molecular cloning and characterization of antimicrobial peptides from skin of Hylarana guentheri, Acta Biochim Biophys Sin, 2017, 49(5), 450–457. Lyu JC, Liu Y, An TC, Liu YJ, Wang MCRG, Song YT, Zheng FF, Wu D, Zhang YX*, Deng SM. Purifcation and characterization of a trypsin inhibitor from the seeds of Artocarpus heterophyllus Lam, Acta Biochim Biophys Sin, 2015, 47(5): 376-382. An TC, Dong Z, Lv JC, Liu YJ, Wang MCRG, Wei SS, Song YT, Zhang YX*, Deng SM. Purification and characterization of a salt-tolerant cellulase from the mangrove oyster, Crassostrea rivularis, Acta Biochim Biophys Sin, 2015, 47(4): 299-305. An TC, Lyu JC, Jia WX, Wang MCRG, Wei SS, Zhang YX*. Role of macrobenthic fauna in mangrove carbon fluxes indicated by their cellulase and hemicellulase activities, Marine Biology Research, 2014, 10(9): 934–940. Zhang YX*, Chen CW, Wang MCRG, Wei SS, Guan H, Chi TT, Qi XZ, Hu WT. Purification and Characterization of Albumin from Frog Skin of Duttaphrynus melanostictus, Protein J, 2011, 30(7): 464-470. Zhang YX*, Wang MCRG, Wei SS, Isolation and characterization of a trypsin inhibitor from the skin secretions of Kaloula pulchra hainana, Toxicon, 2010, 56(4): 502-507.