个人简介
罗素兰，女，博士，博士生导师，长江学者特聘教授，教育部“创新团队”带头人，中组部“全国杰出专业技术人才”，全国优秀科技工作者，国务院特贴专家等。现为海南大学热带生物资源教育部重点实验室主任，海南大学生命科学与药学院副院长（主持行政工作），海口市海洋药物重点实验室主任，首批全国高校“双带头人”教师党支部书记，海南省妇联副主席（兼职）等。长期从事海洋药物与生物技术领域的教学与科研工作。多次到美国犹他大学、澳大利亚昆士兰大学、英国牛津大学、俄罗斯科学院、法国国家科研中心等做访问学者。
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Sulan Luo*(通讯作者), DongtingZhangsun, Peta J. Harvey, Quentin Kaas, Yong Wu, Xiaopeng Zhu, Yuanyan Hu, Xiaodan Li, Victor Tsetlin，Melissa McIntyre, Cheryl Dowell, James C. Baxter, Keith S Elmslie, David J. Craik, and J. Michael McIntosh.Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist.Proc Natl Acad Sci U S A (PNAS). 2015, 112(30): E4026-4035.
DongtingZhangsun, Xiaopeng Zhu, Yong Wu, Yuanyan Hu, Quentin Kaas, David J. Craik, J. Michael McIntosh, andSulan Luo*(通讯作者). Key Residues in the Nicotinic Acetylcholine Receptor β2 Subunit Contribute to α-Conotoxin LvIA Binding. J Biol Chem, 2015, 290(15): 9855–9862.
Jinpeng Yu, Xiaopeng Zhu, Peta J. Harvey, Quentin Kaas, Dongting Zhangsun*, David J Craik, Sulan Luo*(通讯作者). A Single Amino Acid Substitution in α-Conotoxin TxID Reveals a Specific α3β4 Nicotinic Acetylcholine Receptor Antagonist.J Med Chem,2018, 139: 226-237
Jinpeng Yu, Xiaopeng Zhu, Lu Zhang, Denis Kudryavtsev, Igor Kasheverov, Yumiao Lei, DongtingZhangsun*, Victor Tsetlin**,Sulan Luo***(通讯作者). Species Specificity of Rat and Human α7 Nicotinic Acetylcholine Receptors towards Different Classes of Peptide and Protein Antagonists.Neuropharmacology,2018, 139: 226-237.
Yong Wu, DongtingZhangsun, Xiaopeng Zhu, Quentin Kaas, ManqiZhangsun, Peta J. Harvey, David J. Craik, J. Michael McIntosh, andSulan Luo*(通讯作者).α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors.J Med Chem.2017, 60(13):5826-5833.
DongtingZhangsun, Xiaopeng Zhu, Quentin Kaas, Yong Wu, David J. Craik, J. Michael McIntosh, andSulan Luo*(通讯作者). αO-Conotoxin GeXIVA Disulfide Bond Isomers Exhibit Differential Sensitivity for Various Nicotinic Acetylcholine Receptors but Retain Potency and Selectivity for the Human α9α10 Subtype.Neuropharmacology, 2017,127:243-252.
Manyu Xu, Xiaopeng Zhu, Jinfang Yu, Jinpeng Yu,Sulan Luo*(通讯作者), Xinquan Wang*. The crystal structure of Ac-AChBP in complex with α-conotoxin LvIA reveals the mechanism of its selectivity towards different nAChR subtypes.Protein & Cell, 2017,8(9):675-685.
Bo Lin, Manyu Xu, Xiaopeng Zhu, Yong Wu, Xi Liu, DongtingZhangsun, Yuanyan Hu, Shi-Hua Xiang, Igor E. Kasheverov, Victor I. Tsetlin, XinquanWang,* andSulan Luo*(通讯作者). From crystal structure of α-conotoxin GIC in complex with Ac-AChBP to molecular determinants of its high selectivity for α3β2 nAChR.Scientific Reports. 2016, 6: 22349
DongtingZhangsun, Xiaopeng Zhu, Quentin Kaas, Yong Wu, David J. Craik, J. Michael McIntosh, andSulan Luo*(通讯作者). αO-Conotoxin GeXIVA Disulfide Bond Isomers Exhibit Differential Sensitivity for Various Nicotinic Acetylcholine Receptors but Retain Potency and Selectivity for the Human α9α10 Subtype.Neuropharmacology, 2017, 127:243-252.
Xiaodan Li, Yuanyan Hu, Yong Wu, Yi Huang, Shurun Yu, Qing Ding, DongtingZhangsun,Sulan Luo*(通讯作者). Anti-hypersensitive effect of intramuscular administration of αO-conotoxin GeXIVA[1,2] and GeXIVA[1,4] in rats of neuropathic pain.Prog Neuropsychopharmacol Biol Psychiatry, 2016, 66: 112-119.
Sulan Luo*(通讯作者), DongtingZhangsun, Christina I. Schroeder,Xiaopeng Zhu, Yuanyan Hu, Yong Wu, Maegan M. Weltzin, Spencer Eberhard, Quentin Kaas, David J. Craik, J. Michael McIntosh,and Paul Whiteaker. A novel α4 / 7-conotoxin LvIA from Conus lividus that selectively blocks α3β2 vs. α6 / α3β2β3 nicotinic acetylcholine receptors.FASEB J. 2014, 28 (4): 1842-1853.
Sulan Luo*(通讯作者),DongtingZhangsun, Xiaopeng Zhu, Yong Wu, Yuanyan Hu, Sean Christensen, Peta J. Harvey, MuharremAkcan, David J. Craik and J. Michael McIntosh. Characterization of a Novel Alpha-Conotoxin TxID from Conus textile that Potently Blocks rat Alpha3beta4 Nicotinic Acetylcholine Receptors.J Med Chem.2013, 56, 9655?9663.
Sulan Luo*(通讯作者), Dongting Zhangsun, Yong Wu, Xiaopeng Zhu, Yuanyan Hu, Melissa McIntyre , Sean Christensen, Muharrem Akcan, David J. Craik, and J. Michael McIntosh. Characterization of a Novel α-Conotoxin from Conus textile that Selectively Targets a6/a3b2b3 Nicotinic Acetylcholine Receptors.J Biol Chem, 2013, 288(2): 894–902, 2013.
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