贾爱群 - 海南大学 - 生命科学与药学院

个人简介

教育背景 2001.1-2004.7 中国科学院昆明植物研究所，理学博士（植物化学-天然药物化学）； 1998.9-2001.1 无锡轻工大学（今江南大学），工学硕士（应用化学-天然产物化学）； 1989.9-1993.7 河南师范大学，理学学士（化学）。工作经历： 2019.3-至今海南大学生命科学与药学院，教授，博士生导师； 2017.7-2019.3 海南大学海洋学院药学系，教授，博士生导师； 2012.4-2017.7 南京理工大学环境与生物工程学院，教授，博士生导师； 2008.2-2009.3 德国马普学会耶拿化学生态研究所，博士后； 2006.7-2012.4 南京理工大学，副教授，硕士生导师； 2005.12-2006.7 香港中文大学，Research Associate； 2004.7-2005.12 江苏正大天晴制药，新药研发工程师； 1993.7-1998.9 洛阳师专（今洛阳师范学院）化学系，助教-讲师

研究领域

有重要生理活性天然产物的研究与开发。特色（海洋）药（食）用生物资源中（新颖结构）有机化合物的发现与以非经典抗菌为主的重要药学活性评价与机制研究；基于新合成方法的有重要生理活性天然有机化合物的化学修饰；功能天然有机小分子的化学生态学或化学生物学行为研究

近期论文

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Zhou, J. W., Ruan, L. Y., Chen, H. J.; Luo, H. Z., Jiang, H., Wang, J. S.*,Jia, A. Q.*, (2019), Inhibition of quorum sensing and virulence in Serratia marcescens by hordenine,J. Agri. Food Chem., 67(3), 784-795. Liu, Y., Xie, F.,Jia, A. Q. *, Li, X. W. *, (2018), Cp*Co(III)-Catalyzed amidation of olefinic and aryl C-H bonds: Highly selective synthesis of enamides and pyrimidones,Chemical Communications, 54, 4345-4348. Zhou, J. W., Luo, H. Z., Jiang, H., Jian, T. K., Chen, Z. Q.,Jia, A. Q.*, (2018), Hordenine, a novel quorum sensing inhibitor and anti-biofilm agent againstPseudomonas aeruginosa,J. Agri. Food Chem., 66(7):1620-1628. Yang, R., Guan, Y., Wang, W. X., Chen, H.J., He, Z.C.,Jia, A. Q.*, (2018), Antioxidant capacity of phenolics inCamellia nitidissima Chi flowers and their identification by HPLC Triple TOF MS/MS,PlosOne, 13(4), e0195508. Zhou, J. W., Chen, T. T., Tan, X. J., Sheng, J. Y.,Jia, A. Q.*, (2018), Can resveratrol, a quorum sensing inhibitor, function as an aminoglycoside antibiotic-mate againstPseudomonas aeruginosa?International Journal of Antimicrobial Agents, 52(1), 35-41. Yang, R., Zhou, J. W., Sun, B., Wang, Z. N., Chen, H. J., He, Z. C.,Jia, A. Q.*, (2018), Phytochemicals fromCamellia nitidissima Chi flowers reduce the pyocyanin production and motility ofPseudomonas aeruginosa PAO1,Frontiers in Microbiology, 8, 2640-2653. Yang, R., Wang, W.X., Chen, H.J., He, Z.C.,Jia, A.Q.*, (2018), The inhibition of advanced glycation end-products by five fractions and three main flavonoids from Camellia nitidissima Chi flowers,Journal of Food and Drug Analysis, 26, 252-259. Zhou, J. W., Bi, S. Y., Chen, H. J., Chen, T. T., Yang, R., Li, M. H., Fu, Y. H.,Jia, A. Q.*, (2017), Anti-Biofilm and Antivirulence Activities of Metabolites from Plectosphaerella cucumerinaagainst Pseudomonas aeruginosa,Frontiers in Microbiology, 8, 769-786. Chen, T. T., Sheng, J. Y., Fu, Y. H., Li, M. H., Wang, J. S.*,Jia, A. Q.*, (2017),1H-NMR-Based Global Metabolic Studies of Pseudomonas aeruginosa upon Exposure of the Quorum Sensing Inhibitor Resveratrol,Journal of Proteome Research, 16 (2), 824-830. Chen, X. D., Tian, D. G., Abeer, H Allah EF, A, Hu, X. Y. *,Jia, A. Q.*, (2016), The role of nitric oxide signaling in response to salt stress inChlamydomonas reinhardtii,Planta, 244 (3), 651-69. Wang, W. X., Liu, H. Y., Wang, Z. N., Qi, J., Yuan, S. T., Zhang, W. J., Chen, H. J., Finley, J. W, Gu, L. W.*,Jia, A. Q.*, (2016), Phytochemicals fromCamellia nitidissima Chi inhibited the formation of advanced glycation end-products by scavenging methylglyoxal,Food Chem, 205, 204-211. Sheng, J. Y., Chen, T. T., Tan, X. J., Chen, T.,Jia, A. Q.*, (2015), The quorum-sensing inhibiting effects of stilbenoids and their potential structure-activity relationship,Bioorganic & Medicinal Chemistry Letters, 25(22), 5217-20. Xu, H. D., Wang, J. S.*, Li, M. H., Liu, Y., Chen, T., Jia, A. Q.*, (2015),1H NMR based metabolomics approach to study the toxic effects of herbicide butachlor on goldfish (Carassius auratus).Aquatic Toxicology, 159, 69-80. Wang, W. X., Qi, Y. J., Rocca, J, Sarnoski, P.,Jia, A. Q.*, Gu, L. W. *, (2015), Scavenging of Toxic Acrolein by Resveratrol and Hesperetin and Identification of Adducts,J. Agri. Food Chem, 63(43), 9488-95. Chen, J. H., Lin, S. S., Yuan, S. T., Shi, J. S.*,Jia, A. Q.*, (2015), The extract, LXB-1, from the barks ofLiriodendron×hybrid, induced apoptosis via Akt, JNK and ERK1/2 pathways in A549 lung cancer cells,Zeitschrift für Naturforschung C (ZNC), 70 (11-12), 305-311. Yang, D. T, Lin, S. S., Chen, J. H., Yuan, S. T., Shi, J. S.*, Wang, J. S., Jia, A. Q.*, (2015), (+)- and (?)-liriodenol, a pair of novel enantiomeric lignans fromLiriodendron hybrid, Bioorganic & Medicinal Chemistry Letters, 25 (9), 1976-8. Tan, X. J., Qin, N., Sheng, J. Y., Peng, X. H.*,Jia, A. Q.* (2015), Transcriptome analysis of the biofilm formed by methicillinsusceptibleStaphylococcus aureus,Scientific Reports, 5, 11997.