研究领域
(1) 药物分子结构导向的绿色合成方法学研究
(2) 新颖结构药物的设计、合成及定量构效关系研究
(3) 药物的绿色合成工艺开发
近期论文
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1.Guofu Zhang, Yuxin Luan, Xingwang Han, Yong Wang, Xin Wen and Chengrong Ding*. Pd(l-proline)2 complex: an efficient catalyst for Suzuki–Miyaura coupling reaction in neat water, Appl. Organomet. Chem., 2014, 28(5), 332-336.
2.Guofu Zhang, Xingwang Han,Yuxin Luan, Yong Wang, Xin Wen, Chengrong Ding*. L-Proline: an efficient N,O-bidentate ligand for copper-catalyzed aerobic oxidation of primary and secondary benzylic alcohols at room temperature, Chem. Commun., 2013, 49, 7908-7910.
3.Guofu Zhang, Xingwang Han, Yuxin Luan, Yong Wang, Xin Wen, Chengrong Ding*. A palladium complex with functionalized β-cyclodextrin: a promising catalyst featured by recognition ability for Suzuki-Miyaura coupling reaction in water, Green Chem., 2013, 15 (8), 2081-2085.
4.Guofu Zhang, Xin Wen, Yong Wang, Xingwang Han, Yuxin Luan, Lebin Zheng, Chengrong Ding* and Xiaoji Cao*. In situ generation of active species “NO” for the aerobic oxidative deprotection of aldoximes catalyzed by FeCl3/TEMPO, RSC Adv., 2013, 3(45), 22918-22921.
5.Guofu Zhang, Xingwang Han, Yuxin Luan, Yong Wang, Xin Wen, Li Xu*, Chengrong Ding and Jianrong Gao. Copper-catalyzed aerobic alcohol oxidation under air in neat water by using a water-soluble ligand, RSC Adv., 2013, 3, 9255-19288.
6.Guofu Zhang, Xiaoqiang Xie, Yong Wang, Xin Wen, Yun Zhao, Chengrong Ding*. Highly selective Wacker reaction of styrene derivatives: a green and efficient aerobic oxidative process promoted by benzoquinone/NaNO2/HClO4 under mild conditions, Org. Biomol. Chem., 2013, 11(18),2947-2950.
7.Guofu Zhang, Yong Wang, Xin Wen, Chengrong Ding*, Ying Li. Dual-functional click-triazole: a metal chelator and immobilization linker for the construction of heterogeneous palladium catalyst and its application for the aerobic oxidation of alcohols, Chem. Commun., 2012, 48(24), 2979-2981.
8.Guofu Zhang, Xiaobao Zhao, Yunbing Yan, Chengrong Ding*, Direct arylation under catalysis of an oxime-derived palladacycle: search for a phosphane-free method, Eur. J. Org. Chem., 2012, (4): 669-672.
9.Guofu Zhang, Xin Wen, Yong Wang, Weimin Mo*, Chengrong Ding*. Sodium nitrite-catalyzed aerobic oxidative deoximation under mild conditions, J. Org. Chem. 2011, 76(11), 4665-4668.
10.Li Xu, Yong Wang, Xin Wen,Chengrong Ding, Guofu Zhang, * Xinmiao Liang. Aerobic oxybromination of phenols catalyzed by sodium nitrite under mild conditions, Synlett, 2011, (15): 2265-2269.
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