个人简介
浙江大学教授,博士生导师。1985年2月毕业于浙江农业大学兽医专业,获硕士学位;2002年8月毕业于瑞典农业大学兽医专业,获哲学博士。1999年9月至2018年4月期间任浙江大学动物医学系系主任。主要从事中兽医学教学和科学研究。主要研究方向为中药免增强剂和奶牛疾病防治。国内外发表研究论文200余篇,获授权国家发明专利19项,新兽药证书2个;2014、2015、2016和2017年连续四年被列入Elsevier发布的中国高被引学者(Most Cited Chinese Researchers)榜单。
教学与课程
本科生课程:
中兽医学
兽医针灸
研究生课程:
兽医学进展
高级动物免疫学专题
兽医中药专题
泌乳科学
科研
1.家畜围产期群发普通病诊断与防控技术研究,国家科技部,2017-10-01至2021-12-31
2.植物油佐剂ZE515促进猪对口蹄疫疫苗免疫应答及其机理研究,国家基金委,2017-01-01至2020-12-31
3.人参皂甙Re和Rg1抗细菌内毒素LPS的作用及其机理研究,国家基金委,2014-01-01至2017-12-31
4.中兽药生产关键技术研究与应用,国家农业部,N20130123,2013-01-01至2017-12-31
研究与成果
主持国家和省部级以及企业委托项目20余项,研究内容涉中药免疫佐剂和奶牛乳房炎防治。
研究成果
1.人参叶口服液,农业部新兽药证书,(2012)新兽药证字38号。
2.人参茎叶总皂苷颗粒,农业部新兽药证书,(2017)新兽药证字20号。
3.新型抗感染性疾病中兽药创制关键技术,山东省技术发明奖,三等,山东省人民政府,2016-1,2
实验室介绍
中兽医实验室主要从事中兽医学的教学和科学研究。教学方面主要承担中兽医学、兽医针灸学和兽医中药等课程的教学任务。科学研究的主要研究方向有(1)畜禽疾病的诊断及防治和(2)中草药调节动物的免疫功能。本实验室已经完成或正在进行研究项目得到了国家自然科学基金、科技部国家科技支撑计划、博士后科学基金、农业部公益性行业科研专项、国家重点研发项目、浙江省科技厅、浙江省自然科学基金、杭州市科技局、国际科学基金(IFS)以及有关企事业单位的资助。本实验室拥有进行中草药提取与分离、免疫学实验、细胞学实验、奶牛乳房诊断的常规仪器设备。为国家培养人才是本实验室的主要任务之一。目前为止,在本实验室攻读学位并且已经毕业的学生有:母安雄、拉彪(尼日利亚)、杜爱芳、林峰强、臧力铭、陈婉君、王芳、黄怡君、若杰普特(巴基斯坦)、孙建华、罗江华、姜也文、肖琛闻、包省军、凯丝琳(泰国)、曹立亭、李建平、宋晓明、陈星、李瑞丽、吴丽华、袁林、吴俊强、何挺、翟丽娟、燕霞、陈俭、樊青、潘韬、李禹涛、谢锋、张丽佳、薛银、张丽丽、卢一松、苏菲、俞佳、王萌、许晔、苏小艳、王星星、倪敬轩、李任军、郭蕊、徐伟、张岑容、何珊珊、梁思源;兄弟院学生校来本实验室做学位论文研究的有:韦晓洁、陈志华、王伟玉、吴强、蒋桂梅、王云皓、马艳粉;本实验室还接收本科学生进行毕业论文和SRPT项目研究。
近期论文
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近五年发表论文
Xiao CW(肖琛闻),Rajput ZI,Bao G(鲍国连),Hu SH(胡松华)and N.A.Soomro3.Short communication.Enhancement of the immune responses to vaccination against foot-and-mouth disease in mice by oral administration of Quillaja saponaria-A and extracts of Cochinchina momordica seed.Span.J.Agric.Res.2013,11(1):84-88.
Feng X(谢锋),Sakwiwatkul K,Zhang CR(张岑容),Wang YM(王越珉),Zhai LJ(翟丽娟),Hu SH(胡松华).Atractylodis macrocephalae Koidz.polysaccharides enhance both serum IgG response and gut mucosal immunity.Carbohyd.Polym.2013,91(1):68-73.
Zhang CR(张岑容),Wang YM(王越珉),Wasng M(王萌),Su XY(苏小艳),Lu YS(卢一松),Su F(苏菲),Hu SH(胡松华).Rapeseed oil and ginseng saponins work synergistically to enhance Th1 and Th2 immune responses induced by the foot-and-mouth disease vaccine.Clin.Vaccine Immunol.2014,21(8):1113-1119.
Zhai LJ(翟丽娟),Wang YM(王越珉),Yu J(俞佳),Hu SH(胡松华).Enhanced immune responses of chickens to oral vaccination against infectious bursal disease by ginseng stem-leaf saponins.Poultry Sci.2014,93(10):2473-2481.
Su XY(苏小艳),Pei ZY(裴增扬),Hu SH(胡松华).Ginsenoside Re as an adjuvant to enhance the immune response to the inactivated rabies virus vaccine in mice.Int.Immunopharmacol.2014,20(2):283–289.
Xu W(徐伟),Guan R(关然),Lu YS(卢一松),Su XY(苏小艳),Xu(许晔),Du AF(杜爱芳)and Hu SH(胡松华).Therapeutic effect of polysaccharide fraction of Atractylodis macrocephalae Koidz.in bovine subclinical mastitis.BMC veterinary research,2015,11(1):1.P405-413
Su F(苏菲),Xue Y(薛银),Wang YM(王越珉),Zhang LL(张丽丽),Chen WX(陈王学),Hu SH(胡松华).Protective Effect of Ginsenosides Rg1 and Re on Lipopolysaccharide-Induced Sepsis by Competitive Binding to Toll-Like Receptor 4.Antimicrobial agents and chemotherapy,2015,59(9):5654-5663.
Guan R(关然),Xu W(徐伟),Pan T(潘韬),Su XY(苏小艳),Hu SH(胡松华).Subcutaneous injection of thymopentin in the area of the supramammary lymph node to reduce milk somatic cell count in subclinically mastitic cows.Journal of veterinary pharmacology and therapeutics,2015,39:72-77.
Yu J(俞佳),Chen YJ(陈玉娇),Zhai LJ(翟丽娟),Zhang LL(张丽丽),Xu Y(许晔),Wang SH(王晟昊),Hu SH(胡松华).Antioxidative effect of ginseng stem-leaf saponins on oxidative stress induced by cyclophosphamide in chickens.Poultry science,2015,94:927-933.
Yu J(俞佳),Shi FS(师福山),Hu SH(胡松华).Improved immune responses to a bivalent vaccine of Newcastle disease and avian influenza in chickens by ginseng stem-leaf saponins.Veterinary immunology and immunopathology,2015,167(3):147-155.
11.Ni JX(倪敬轩),Bi SC(毕师诚),Xu W(徐伟),Zhang CR(张岑容),Lu YS(卢一松),Zhai LJ(翟丽娟),Hu SH(胡松华).Improved immune response to an attenuated pseudorabies virus vaccine by ginseng stem-leaf saponins(GSLS)in combination with thimerosal(TS).Antiviral Research,2016:92-98.
12.Su F(苏菲),Girishchandra B Patel,Hu SH(胡松华),Chen WX(陈王学).Induction of mucosal immunity through systemic immunization:phantom or reality?Human Vaccines&Immunotherapeutics:2164-5515.
13.Li RJ(李任军),Ma YF(马艳粉),Zhai LJ(翟丽娟),Lu YS(卢一松),Chi XQ(迟晓庆),Wu JS(吴旧生),Hu SH(胡松华).Enhanced Immune Response to Foot-and-Mouse Disease Vaccine by Oral Administration of Ginseng Stem-Leaf Saponins.Immunopharmacology and Immunotoxicology,2016.38(4):257-263
1673-1581.
14.Su XY(苏小艳),Xu W(徐伟),Guan R(关然),Wang YH(王云皓),Wu J(吴洁),Zhai LJ(翟丽娟),Chen G(陈刚),Hu SH(胡松华).Adjuvant effect of docetaxel on HPV16 L2E6E7 fusion protein vaccine in a mouse model.Int.Immunol.38(2016)16–25.P494-503
15.Chi XQ(迟晓庆),Bi SC(毕师诚),Xu W(徐伟),Zhang Y(张勇),Liang SY(梁思源),Hu SH(胡松华).Oral administration of tea saponins to relive oxidative stress and immune suppression in chickens.Poultry Sci.96(2017):3058–3067.
16.Xu W(徐伟),Guan R(关然),Shi FS(师福山),Du AF(杜爱芳),Hu SH(胡松华).Structural analysis and immunomodulatory effect of polysaccharide from Atractylodis macrocephalae Koidz.on bovine lymphocytes.Carbohyd.Polym.174(2017)1213–1223.
17.Xu W(徐伟),Du AF(杜爱芳),Hu SH(胡松华).Transcriptome analysis of bovine lymphocytes stimulated by Atractylodis macrocephalae Koidz.polysaccharides in vitro.Vet.Immunol.Immunop 196(2018)30–34.18.Zhang CR(张岑容),Xu W(徐伟),Chen J(陈检),Guan R(关然),Bi SC(毕师诚),Jin HB(金海波),Cui XM(崔雪梅),Shi FS(师福山),Hu SH(胡松华).Soybean oil containing ginseng saponins as adjuvants promotes production of cytokines and enhances immune responses to foot-and-mouth disease vaccine.Microbiol Immunol 2018;62:187–194.
19.Bi SC(毕师诚),Chi XQ(迟晓庆),Zhang Y(张勇),Ma XD(马晓丹),Liang SY(梁思源),Wang YM(王越珉),Hu SH(胡松华).Ginsenoside Rg1 enhanced immune responses to infectious bursal disease vaccine in chickens with oxidative stress induced by cyclophosphamide.Poultry Sci(2018)0:1–10.
学术兼职
世界中兽医学会(WATCVM)执行委员会委员、亚洲传统兽医学会副理事长、中国畜牧兽医学会中兽医学分会副理事长,中华人民共和国兽药典第三、四、五届委员会委员,农业部第三、四、五、六届兽药审评专家。