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Chen, C. C.,* Zhang, L., Yu, X., Ma, L., Ko, T. P., Guo, R. T.* Versatile cis-isoprenyl Diphosphate Synthase Superfamily Members in Catalyzing Carbon–Carbon Bond Formation. ACS Catalysis, 2020, 10, 4717-4725 (Review, ACS Editors’ Choice, Cover story) Chen, C. C., Dai, L., Ma, L.,* Guo, R. T.* Enzymatic degradation of plant biomass and synthetic polymers Nature Reviews Chemistry, 2020, 4, 114-126 (Review, Cover story) Yang, Y., Li, L., Yuan, L., Zhou, X., Duan, J., Xiao, H., Cai, N., Han, S., Ma, X., Liu, W., Chen, C. C., Wang, L., Li, X., Chen, J., Kang, N., Chen, J., Shen, Z., Malwal, S. R., Liu, W., Shi, Y., Oldfield, E., Guo, R. T., Zhang, Y. A Structural change in butyrophilin upon phosphoantigen binding underlies phosphoantigen-mediated Vgamma9Vdelta2 T cell activation. Immunity, 2019, 50, 1043-1053 Sun, H., Ko, T. P., Liu, W., Liu, W., Zheng, Y., Chen, C. C.,* Guo, R. T.* Structure of an antibiotic-synthesizing UDP-glucuronate 4-epimerase MoeE5 in complex with substrate. Biochemical and Biophysical Research Communications, 2019, 521, 31-36. Kuo, C. J., Gao, J., Huang, J. W., Ko, T. P., Zhai, C., Ma, L., Liu, W., Dai, L., Chang, Y. F., Chen, T. H., Hu, Y., Yu, X., Guo, R. T.,* Chen, C. C.* Functional and structural investigations of fibronectin-binding protein Apa from Mycobacterium tuberculosis. (2019) Biochimica et Biophysica Acta. General subjects, 2019, 1863, 1351-1359 Tang, X.# Xue, J.#, Yang, Y., Ko, T. P., Chen, C.Y., Dai, L., Guo, R.T. , Zhang, Y.,* Chen C. C.* Structural insights into the calcium dependence of Stig cyclases. RSC Advances, 2019, 9, 13182. Ma, J., Ko, T. P., Yu, X.,Zhang, L., Ma, L., Zhai, C., Guo, R. T., Liu, W., Li, H., Chen, C. C.* Structural insights to heterodimeric cis-prenyltransferases through yeast dehydrodolichyl diphosphate synthase subunit Nus1. Biochemical and Biophysical Research Communications, 2019, 515, 621-626. Zhang, L., Ko, T. P., Malwal S. R., Liu W., Zhou S., Oldfield E., Guo R. T.,* and Chen, C. C.* Complex structures of MoeN5 with substrate analogues suggest sequential catalytic mechanism, Biochemical and Biophysical Research Communications, 2019, 511, 800-805 Chang, Z., Ansbacher, T., Zhang, L., Yang, Y., Ko, T. P., Zhang, G., Liu, W., Huang, J. W., Dai, L., Guo, R. T., Major, D. T.,* Chen, C. C.* Crystal structure of LepI, a multifunctional SAM-dependent enzyme which catalyzes pericyclic reactions in leporin biosynthesis, Organic Biomolecular Chemistry, 2019, 17, 2070-2076. (Cover story) Chen, C. C.,# Hu, X.,# Tang, X.,# Yang, Y.,# Ko, T. P., Gao, J., Zheng, Y., Huang, J. W., Yu, Z., Li, L., Han, S., Cai, N., Zhang, Y.,* Liu, W.,* Guo, R. T.* The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement. Angewandte Chemie International Edition, 2018, 57, 15060-15064. (Cover story) Chen, C. C.,# Han, X.,# Ko, T. P., Liu, W.,* Guo, R. T.* Structural studies reveal the molecular mechanism of PETase. FEBS Journal, 2018, 285, 3717-3723. Zheng, Y.,# Liu, W.,# Chen C. C.,# Hu, X., Liu, W., Ko, T. P., Tang, X., Wei, H., Huang, J. W., Guo, R. T.* Crystal Structure of a Mycoestrogen-Detoxifying Lactonase from Rhinocladiella mackenziei: Molecular Insight into ZHD Substrate Selectivity. ACS Catalysis. 2018, 8, 4294-4298. Han, X.,# Liu, W.,# Huang, J. W.,# Ma, J., Zheng, Y., Ko, T. P., Xu, L., Cheng, Y. S., Chen, C. C., Guo, R. T.* Structural insight into catalytic mechanism of PET hydrolase. Nature Communications, 2017, 13, 2106. Zhang, L.,# Chen, C. C.,# Ko, T. P.,# Huang, J. W., Zheng, Y., Liu, W., Wang, I., Malwal, S. R., Feng, X., Wang, Ke., Huang, C. C., Hsu, S. T., Wang, A. H., Oldfield, E.,* and Guo, R. T.* Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyl Transferase MoeN5, Angewandte Chemie International Edition, 2016, 55, 4716-4720. Xu, Z.,# Liu, W.,# Chen, C. C.,# Li Q., Huang, J. W., Ko, T. P., Liu, G., Liu, W., Peng, W., Cheng, Y. S., Chen, Y., Jin, J., Li, H.,* Zheng, Y.,* Guo, R. T.* Enhanced α‑Zearalenol Hydrolyzing Activity of a Mycoestrogen Detoxifying Lactonase by Structure-Based Engineering. ACS Catalysis, 2016, 6, 7657-7663. (Cover story) Liu, M.,# Chen, C. C.,# Chen, Lu.,# Xiao, X., Zheng, Y.,Huang, J. W., Liu, W., Ko, T. P., Cheng, Y. S., Feng, X., Oldfield, E.,* Guo, R. T.,* and Ma, Y.* Structure and Function of a “Head-to-Middle” Prenyltransferase: Lavandulyl Diphosphate Synthase, Angewandte Chemie International Edition, 2016, 55, 4721-4724. (Cover story) Huang, J. W.,# Liu, W.,# Lai, H. L., Cheng, Y. S., Zheng, Y., Li, Q., Sun, H., Kuo, C. J., Guo, R. T.,* Chen, C. C.* Crystal structure and genetic modifications of FI-CMCase from Aspergillus aculeatus F-50. Biochemical and Biophysical Research Communications, 2016, 16, 565-572. Yang, Y.,# Ko, T. P.,# Chen, C. C.,# Huang, G., Zheng, Y., Liu, W., Wang, I., Ho, M., Hsu, S., O'Dowd, B., Huff, H., Huang, C. H., Docampo, R., Oldfield, E.,* Guo, R. T.,* Structures of Trypanosome Vacuolar Soluble Pyrophosphatases: Anti-Parasitic Drug Targets. ACS Chemical Biology, 2016, 11, 1362-1371. Haywood, J., Qi, J., Chen, C. C., Lu, G., Liu, Y., Yan, J., Shi, Y., and Gao, G. F. Structural basis of collagen recognition by human osteoclast-associated receptor and design of osteoclastogenesis inhibitors, PNAS, 2016, 113, 1038-1043. Cheng, Y. S.,# Chen, C. C.,# Huang, J. W., Ko, T. P., Huang, Z., and Guo, R. T.* Improving the catalytic performance of a GH11 xylanase by rational protein engineering, Applied Microbiology and Biotechnology, 2015, 99, 9503-9510.