Berthold Hocher - 湖南师范大学

个人简介

BertholdHocher，德国籍，教授。现为湖南师范大学医学院“外专百人计划”讲座教授，德国海德堡大学曼海姆医学院肾病内分泌与风湿科教授。Hocher教授是国际上知名的心血管-肾病学研究专家，是欧洲最早从事健康与疾病的发育起源学说的研究专家之一。Hocher教授担任JournalofHypertension等杂志学术编委。至今已获得德国自然科学研究基金5项，欧洲研究基金1项，Fressenius研究基金4项，多项企业合作基金等资助，已获得多项欧洲及美国专利，已发表SCI收录的文章280篇，总IF:1039.2,总引用次数：5126，总H-指数：38。

研究领域

专利（可选）： 1.NON-OXIDIZED,BIOLOGICALACTIVEPARATHYROIDHORMONEDETERMINESMORTALITYIN，CountryofGranting：USA，Owner：FranzPaulArmbruster,BertholdHocher,HeinzJuergenRoth 2.Useofadpp-4inbitorinpodocytesrelateddisordersand/ornephroticsyndrome,CountryofGranting：USA，Owner：ThomasKlein,MaximilianvonEYNATTEN,BertholdHocher,MichaelMark,YuliyaSHARKOVSKA,Less 3.Meansandmethodsofmeasuringparathyroidhormoneinpatientssuffering,CountryofGranting：EU，Owner：FranzPaulArmbruster,BertholdHocher,HansJuergenGroen,HeinzJuergenRoth 4.MEANSANDMETHODSOFMEASURINGPARATHYROIDHORMONEINPATIENTSSUFFERINGFROMOXIDATIVESTRESS,CountryofGranting：USA，Owner：FranzPaulArmbruster,BertholdHocher,HansJuergenGroen,HeinzJuergenRoth

近期论文

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HocherB,Thöne-ReinekeC,RohmeissP,SchmagerF,SlowinskiT,BurstV,SiegmundF,QuertermousT,NeumayerHH,BauerC,SchleuningWD,TheuringF.Endothelin-1transgenicmicedeveloprenalcysts,interstitialfibrosisandglomerulosclerosisbutnothypertension.JClinInvest99;1380-1389(1997) HocherB,SlowinskiT,StolzeT,PleschkaA,NeumayerHH,HalleH.AssociationofmaternalGproteinß3subunit825Tallelewithlowbirthweight.Lancet,355;1241-1242(2000) FischerederM,LuckowM,HocherB,WüthrichRP,RothenpielerU,SchneebergerH,PanzerU,StahlR,NeumayerHH,HauserIA,BuddeK,NeumayerHH,KrämerBK,LandW,SchlöndorffD.ProlongationofrenaltransplantsurvivalinpatientslackingafunctionalCCchemokinereceptor5(CCR5).Lancet357;1758-1761(2001) PfabT,SlowinskiT,GodesM,HalleH,PriemF,HocherB.Lowbirthweight,ariskfactorforcardiovasculardiseasesinlaterlife,isalreadyassociatedwithelevatedfetalglycosylatedhemoglobinatbirth.Circulation.114(16):1687-92(2006) MitrovicV,SeferovicP,Dodic,D,KrotinM,NeskovicA,DicksteinK,DevoogdH,BöckerC,ZieglerD,GodesM,NajowR,EssersH,VerboomC,HocherB.Cardio-RenalEffectsoftheA1AdenosineReceptorAntagonistSLV320inPatientswithHeartFailure.Circulation:HeartFailure2(6):523-31(2009) NairAV&,,HocherB&,VerkaartS,vanZeelandF,PfabT,SlowinskiT,ChenYP,SchlingmannKP,SchallerA,GallatiS,BindelsRJ,KonradM,HoenderopJG.Lossofinsulin-inducedactivationofTRPM6magnesiumchannelsresultsinimpairedglucosetoleranceduringpregnancy.ProcNatlAcadSciUSA.(2012)&,equalcontributingfirstauthors HorikoshiM,………………,OngKK,VollenweiderP,vanDuijnCM,KoppelmanGH,HattersleyAT,HollowayJW,HocherB,HeinrichJ,PowerC,MelbyeM,GuxensM,PennellCE,BønnelykkeK,BisgaardH,ErikssonJG,WidénE,HakonarsonH,UitterlindenAG,PoutaA,LawlorDA,SmithGD,FraylingTM,McCarthyMI,GrantSF,JaddoeVW,JarvelinMR,TimpsonNJ,ProkopenkoI,FreathyRM.Newlociassociatedwithbirthweightidentifygeneticlinksbetweenintrauterinegrowthandadultheightandmetabolism.NatGenet.45(1):76-82.doi:10.1038/ng.2477(2013) TsuprykovO,AndoR,ReichetzederC,vonWebskyK,AntonenkoV,SharkovskaY,ChaykovskaL,RahnenfuhrerJ,HasanAA,TammenH,AlterM,KleinT,UedaS,YamagishiS,OkudaS,HocherB.TheDPP4inhibitorLinagliptinandtheangiotensinIIreceptorblockertelmisartanshowrenalbenefitbydifferentpathwaysinnon-diabeticratswith5/6nephrectomy.KidneyInt,2016May;89(5):1049-61.doi:10.1016/j.kint.2016.01.016. HocherB,TsuprykovO.Diabeticnephropathy:RenoprotectiveeffectsofGLP1RagonistsandSGLT2inhibitors.NatRevNephrol.2017Dec;13(12):728-730. LiJ,LuYP,TsuprykovO,HasanAA,ReichetzederC,TianM,ZhangXL,ZhangQ,SunGY,GuoJ,GaballaMMS,PengXN,LinG,HocherB.Folatetreatmentofpregnantratdamsabolishesmetaboliceffectsinfemaleoffspringinducedbyapaternalpre-conceptionunhealthydiet.Diabetologia.2018Aug;61(8):1862-1876

学术兼职

1.瑞士伯恩大学客座教授 2.德国柏林洪堡大学夏立特医学院心血管研究中心/药理学研究所（CCR）客座教授 3.勃林格殷格翰医药集团顾问 4.荷兰Wijchen公司顾问 5.欧洲高血压与肾脏病等学会委员 6.德国国家科学基金等资助申请评审员