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1.MinSun,QingqingYuan,MinghuiNiu,HongWang,LipingWen,ChenchengYao,JingmeiHou,ZhengChen,HongyongFu,FanZhou,ChongLi,ShaorongGao,Wei-QiangGao,ZhengLi,ZupingHe*.EfficientGenerationofFunctionalHaploidSpermatidsFromHumanGermlineStemCellsbyThree-DimensionalInducedSystem.CellDeathandDifferentiation,2018,25:747-764.即时IF:11.07
2.HongyongFu#,WenhuiZhang,QingqingYuan,MinghuiNiu,FanZhou,QianqianQiu,GuopingMao,HongWang,LipingWen,MinSun,ZhengLi,ZupingHe*.PAK1PromotestheProliferationandInhibitsApoptosisofHumanSpermatogonialStemCellsviaPDK1/KDR/ZNF367andERK1/2andAKTPathways.MolecularTherapy-NucleicAcid,2018,12:769-786.即时IF:7.05
3.HongyongFu,FanZhou,QingqingYuan,WenhuiZhang,QianqianQiu,XingYu,ZupingHe*.MiRNA-31-5pMediatestheProliferationandApoptosisofHumanSpermatogonialStemCellsviaTargetingJAZF1andCyclinA2.MolecularTherapy-NucleicAcid,2018,14:90-100.即时IF:7.05
4.FanZhou,QingqingYuan,WenhuiZhang,MinghuiNiu,HongyongFu,QainqianQiu,GuipingMao,HongWang,LipingWen,MujunLu,ZhengLi,ZupingHe*.MiR-663aStimulatesProliferationandSuppressesEarlyApoptosisofHumanSpermatogonialStemCellsbyTargetingNFIXandRegulatingCellCycle.MolecularTherapy-NucleicAcid,2018,12:319-336.即时IF:7.05
5.ChenchengYao,QingqingYuan,MinghuiNiu,HongyongFu,FanZhou,WenhuiZhang,HongWang,LipingWen,LigangWu,ZhengLi*,ZupingHe*.DistinctexpressionprofilesandnoveltargetsofmicroRNAsinhumanspermatogonia,pachytenespermatocytesandroundspermatidsbetweenOApatientsandNOApatients.MolecularTherapy-NucleicAcids,2017,9:182-194.即时IF:7.05
6.HongWang,QingqingYuan,MinghuiNiu,WnihuiZhang,LipingWen,HongyongFu,FanZhou,ZupingHe*.TranscriptionalregulationofP63ontheapoptosisofmalegermcellsandthreestagesofspermatogenesisinmice.CellDeathandDisease,2018,9(2):76.即时IF:6.41
7.RuiZhou,JingrouziWu,BangLiu,YiqunJiang,WeiChen,JianLi,QuanyuanHe,ZupingHe*.TherolesandmechanismsofLeydigcellsandmyoidcellsinregulatingspermatogenesis.CellularandMolecularLifeSciences,2019,76,2681-2696.IF:7.014
8.QianqianQiu,XingYu,ChenchengYao,YujunHao,LiqingFan,ChunyiLi,PengXu,GengAn,ZhengLi,ZupingHe*.FOXP3pathogenicvariantscausemaleinfertilitythroughaffectingtheproliferationandapoptosisofhumanspermatogonialstemcells.Aging,2019,11(24):12581-12599.IF:5.51
9.HaoYang,YangLiu,YananHai,YuehuaGong,YingGuo,ShiYang,ZhenzhenZhang,LinhongLiu,ZhengLi,Wei-QiangGao,ZupingHe*.EfficientconversionofmousespermatogonialstemcellstophenotypicandfunctionaldopaminergicneuronsviaPI3K/AktandP21/Smurf2/Nolz1pathway.MolecularNeurobiology,2015,52(3):1654-1669.IF:6.19
10.ShiYang,PingPing,MengMa,PengLi,RuhuiTian,HaoYang,YangLiu,YuehuaGong,ZhenzhenZhang,ZhengLi*,ZupingHe*.Generationofhaploidspermatidswithfertilizationanddevelopmentcapacityfromhumanspermatogonialstemcellsofcryptorchidpatients.StemCellReport,2014,3(4):663-675.IF:7.338
11.YananHai,YunLiu,JingmeiHou,ZhenChen,ZupingHe*.TherolesandregulationofSertolicellsinspermatogenesis.SeminarsinCellandDevelopmentalBiology,2014,29:66-75.IF:6.265
12.MengMa,ShiYang,ZhenzhenZhang,PengLi,YuehuaGong,LinhongLiu,YongZhu,RuhuiTian,YufeiLiu,XiaoboWang,FengLiu,LinHe,YangLiu,HaoYang,ZhengLi,ZupingHe*.Sertolicellsfromnon-obstructiveazoospermiaandobstructiveazoospermiapatientsshowdistinctmorphology,ramanspectrumandbiochemicalphenotype.HumanReproduction,2013,28(7):1863-1673.IF:5.02
13.ChaoYang,ChenchengYao,RuhuiTian,ZijueZhu,LiangyuZhao,PengLi,HuixingChen,YuhuaHuang,ErleiZhi,YuehuaGong,YunjingXue,HongWang,QingqingYuan,ZupingHe*,ZhengLi*.miR-202-3pRegulatesSertoliCellProliferation,SynthesisFunction,andApoptosisbyTargetingLRP6andCyclinD1ofWnt/β-CateninSignaling.MolecularTherapy-NucleicAcids,2018,14:1-19.即时IF:7.05
14.YingGuo,YananHai,ChenchengYao,ZhengChen,JingmeiHou,ZhengLi,ZupingHe*.Long-termcultureandsignificantexpansionofhumanSertolicellswhilstmaintainingstableglobalphenotypeandAKTandSMAD1/5activation.CellCommunicationandSignaling,2015,13:20.IF:5.324
15.ZhenzhenZhang,YuehuaGong,YingGuo,YananHai,HaoYang,ShiYang,YangLiu,MengMa,LinhongLiu,ZhengLi,Wei-QiangGao,ZupingHe*.Directtransdifferentiationofspermatogonialstemcellstomorphological,phenotypicandfunctionalhepatocyte-likecellsviatheERK1/2andSmad2/3signaling,pathwaysandtheinactivationofcyclinA,cyclinBandcyclinE.CellSignalingandCommunications,2013,11:67.IF:5.324
16.ZupingHe#,JijiJiang,MariaKokkinaki,LinTang,WenxianZeng,IanGallicano,InaDobrinski,MartinDym.MiRNA-20andMiRNA-106aRegulateSpermatogonialStemCellRenewalatthePost-TranscriptionalLevelviaTargetingSTAT3andCcnd12.StemCells,2013,31(10):2205~2217.IF:7.74
17.ZupingHe#,JijiJiang,MariaKokkinaki,MartinDym.Nodalsignalingviaanautocrinepathwayisrequiredforproliferationofmousespermatogonialstem/progenitorcellsthroughsmad2/3andOct-4activation.StemCells,2009,27:2580-2590.IF:7.74
18.ZupingHe#,JijiJiang,MariaKokkinaki,NadyGolestaneh,Marie-ClaudeHofmann,MartinDym.Gdnfupregulatesc-FostranscriptionviatheRas/Erk1/2pathwaytopromotemousespermatogonialstemcellproliferation.StemCells,2008,26:266-278.IF:7.74